Generation of 3D Fibroblast-Derived Extracellular Matrix and Analysis of Tumor Cell-Matrix Interactions and Signaling.

Autor: Lay E; Department of Life Sciences, University of Bath, Bath, UK., Grant T; Department of Life Sciences, University of Bath, Bath, UK.; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Walko G; Department of Life Sciences, University of Bath, Bath, UK.; Barts Centre for Squamous Cancer, Institute of Dentistry, Queen Mary University of London, London, UK.; Centre for Oral Immunobiology and Regenerative Medicine, Institute of Dentistry, Queen Mary University of London, London, UK., Jungwirth U; Department of Life Sciences, University of Bath, Bath, UK. u.jungwirth@bath.ac.uk.; Cancer Research Horizons Therapeutic Innovation, Newcastle Drug Discovery Group, Translational and Clinical Research Institute, Newcastle University, Newcastle, UK. u.jungwirth@bath.ac.uk.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2800, pp. 11-25.

Ectopic expression of HNF4α in Het1A cells induces an invasive phenotype.

Autor: Grimaldos Rodriguez C; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Rimmer EF; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Colleypriest B; Department of Gastroenterology, Royal United Hospital Bath, Combe Park, Bath, BA1 3NG, UK., Tosh D; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Slack JMW; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK. Electronic address: bssjmws@bath.ac.uk., Jungwirth U; Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK. Electronic address: uj217@bath.ac.uk.

Publikováno v: Differentiation; research in biological diversity [Differentiation] 2023 Nov-Dec; Vol. 134, pp. 1-10. Date of Electronic Publication: 2023 Aug 23.

Conductive Polymer-Coated 3D Printed Microneedles: Biocompatible Platforms for Minimally Invasive Biosensing Interfaces.

Autor: Keirouz A; Materials for Health Lab, Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK.; Centre for Biosensors, Bioelectronics and Biodevices (C3Bio), University of Bath, Bath, BA2 7AY, UK., Mustafa YL; Materials for Health Lab, Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK.; Centre for Biosensors, Bioelectronics and Biodevices (C3Bio), University of Bath, Bath, BA2 7AY, UK., Turner JG; Materials for Health Lab, Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK.; Centre for Biosensors, Bioelectronics and Biodevices (C3Bio), University of Bath, Bath, BA2 7AY, UK., Lay E; Department of Life Sciences, University of Bath, Bath, BA2 7AY, UK.; Centre for Therapeutic Innovation, University of Bath, Bath, BA2 7AY, UK., Jungwirth U; Department of Life Sciences, University of Bath, Bath, BA2 7AY, UK.; Centre for Therapeutic Innovation, University of Bath, Bath, BA2 7AY, UK., Marken F; Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Leese HS; Materials for Health Lab, Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK.; Centre for Biosensors, Bioelectronics and Biodevices (C3Bio), University of Bath, Bath, BA2 7AY, UK.

Publikováno v: Small (Weinheim an der Bergstrasse, Germany) [Small] 2023 Apr; Vol. 19 (14), pp. e2206301. Date of Electronic Publication: 2023 Jan 03.

Phenanthroindolizidine Alkaloids Isolated from Tylophora ovata as Potent Inhibitors of Inflammation, Spheroid Growth, and Invasion of Triple-Negative Breast Cancer.

Autor: Reimche I; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany.; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany., Yu H; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany., Ariantari NP; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Udayana University, Bali 80361, Indonesia., Liu Z; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany., Merkens K; Department of Chemistry, University of Cologne, 50923 Cologne, Germany., Rotfuß S; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany., Peter K; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany., Jungwirth U; Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath BA2 7AY, UK., Bauer N; European Institute of Molecular Imaging, University of Münster, 48149 Münster, Germany., Kiefer F; European Institute of Molecular Imaging, University of Münster, 48149 Münster, Germany.; Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany., Neudörfl JM; Department of Chemistry, University of Cologne, 50923 Cologne, Germany., Schmalz HG; Department of Chemistry, University of Cologne, 50923 Cologne, Germany., Proksch P; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany., Teusch N; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany.; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 07; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 07.

Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis.

Autor: Jungwirth U; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.; Department of Pharmacy and Pharmacology, Centre for Therapeutic Innovation, University of Bath, Bath, UK., van Weverwijk A; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.; Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Evans RJ; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Jenkins L; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Vicente D; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Alexander J; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Gao Q; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.; Strategic Initiatives, Data Science, The Institute of Cancer Research, Sutton, UK., Haider S; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Iravani M; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Isacke CM; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. clare.isacke@icr.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2021 Jun 10; Vol. 12 (1), pp. 3516. Date of Electronic Publication: 2021 Jun 10.