Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Junguo Hao"'
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 83:266-274
The aim of this study was to clarify the relationship between the concentration of Pluronic P123/F127 block copolymers and P-glycoprotein (P-gp) inhibitory potency. Modulation of multidrug resistance (MDR) by Pluronic P123/F127 was evaluated in P-gp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016cdffb97279f21ce373a12f1e4f8ab
https://doi.org/10.1016/j.ejpb.2012.09.014
https://doi.org/10.1016/j.ejpb.2012.09.014
Publikováno v:
Biomaterials. 33:4741-4751
Three poly(caprolactone)-modified Pluronic P105 polymers (P105/PCLs) were synthesized using commercially available ε-caprolactone monomers and Pluronic P105 copolymers. The chemical structures, compositions and molecular weights of the P105/PCLs wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed85754c7189f2a1a24589f21877f5e
https://doi.org/10.1016/j.biomaterials.2012.03.013
https://doi.org/10.1016/j.biomaterials.2012.03.013
Publikováno v:
Cancer Research. 78:4792-4792
Objective: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Studies indicate that aberrant activation of mesenchymal-epithelial transition factor (c-MET) is associated with HCC development. Blocking c-MET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92cf93f12d6080cafc3c54a9b36015e7
https://doi.org/10.1158/1538-7445.am2018-4792
https://doi.org/10.1158/1538-7445.am2018-4792
Publikováno v:
International Journal of Pharmaceutics. 376:176-185
The objective of this study was to optimize and characterize a novel polymeric mixed micelle composed of Pluronic P123 and F127 loaded with paclitaxel (PTX). A Doehlert matrix design was utilized to investigate the effect of four variables, namely P1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ded61353040bd49fa2c835ac121f5e
https://doi.org/10.1016/j.ijpharm.2009.04.030
https://doi.org/10.1016/j.ijpharm.2009.04.030
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 140
Generally, the major obstacles for efficient gene delivery are cellular internalization and endosomal escape of nucleic acid such as plasmid DNA (pDNA) or small interfering RNA (siRNA). We previously developed Pluronic P123 modified polypropyleneimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee096938615b166fb6a837c5d43f64f
https://pubmed.ncbi.nlm.nih.gov/26741268
https://pubmed.ncbi.nlm.nih.gov/26741268
Publikováno v:
Biomaterials. 45
Multidrug resistance (MDR) remains one of the major reasons for the reductions in efficacy of many chemotherapeutic agents in cancer therapy. As a classical MDR phenotype of human malignancies, the adenosine triphosphate binding cassette (ABC)-transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b39e9ef96dcb0ae5f8c39a5c694b25c
https://pubmed.ncbi.nlm.nih.gov/25662500
https://pubmed.ncbi.nlm.nih.gov/25662500
Publikováno v:
Chromatographia. 70:653-655
A facile, sensitive, and accurate liquid chromatographic method with ultraviolet detection was developed for the determination of caffeic acid tetramer in rat plasma. Chromatographic separation was performed on an YMC C18 10 μm column (250 × 4.6 mm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2f6c8b4cd78ec744ee81d41af4deb08
https://doi.org/10.1365/s10337-009-1175-z
https://doi.org/10.1365/s10337-009-1175-z
Publikováno v:
International Journal of Nanomedicine
Zhiwen Zhang1,2, Xiaoling Fang1, Junguo Hao1, Yajuan Li1, Xianyi Sha1 1Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China; 2S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4929839ce8bbed352ca78cafe53d3954
https://www.dovepress.com/triolein-based-polycation-lipid-nanocarrier-for-efficient-gene-deliver-peer-reviewed-article-IJN
https://www.dovepress.com/triolein-based-polycation-lipid-nanocarrier-for-efficient-gene-deliver-peer-reviewed-article-IJN
Publikováno v:
Biomaterials. 32(25)
The increasing global incidence of malignant melanoma combined with the poor prognosis and low survival rates of patients necessitates the development of new chemotherapeutic strategies. Thus, the objective of this present study was to investigate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822be61acfd6c39f56f8fbe3f87a3741
https://pubmed.ncbi.nlm.nih.gov/21596432
https://pubmed.ncbi.nlm.nih.gov/21596432
Autor:
Yajuan Li, Wei Zhang, Xiaoling Fang, Junguo Hao, Ye Jiang, Zhiwen Zhang, Xianyi Sha, Yuanjia Tang
Publikováno v:
Archives of pharmacal research. 32(7)
Third generation cationic dendritic polymeric polypropyleneimine (PPI) was modified by Pluronic P123 and investigated for gene delivery. The cytotoxicity of P123-PPI was evaluated by the MTT assay and shown to be much lower than that of PPI alone. P1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157d443466a95c776a70a3987eddcc2c
https://pubmed.ncbi.nlm.nih.gov/19641886
https://pubmed.ncbi.nlm.nih.gov/19641886