Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Jungsul Lee"'
Publikováno v:
Journal of Functional Foods, Vol 112, Iss , Pp 105949- (2024)
The aim of the present study is to provide a methodical platform for the development of lead compounds against cholangiocarcinoma. Coptisine was selected as a potential anti-cancer nominee from a pool of phytochemicals using an in silico 3-D docking
Externí odkaz:
https://doaj.org/article/fe68c57768ef45cc955dd8b50e636c15
Autor:
Hyukjun Kwon, Minji Yun, Taek-Hyun Kwon, Minji Bang, Jungsul Lee, Yeo Song Lee, Hae Young Ko, Kyuha Chong
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3168 (2023)
Glioblastoma (GBM) is a representative malignant brain tumor characterized by a dismal prognosis, with survival rates of less than 2 years and high recurrence rates. Despite surgical resection and several alternative treatments, GBM remains a refract
Externí odkaz:
https://doaj.org/article/2d0efe5821b5484381deccfc0f736243
Autor:
Go Hun Seo, Hane Lee, Jungsul Lee, Heonjong Han, You Kyung Cho, Minji Kim, Yunha Choi, Jeongmin Choi, In Hee Choi, Seonkyeong Rhie, Kyu Young Chae, Yoo-Mi Kim, Chong Kun Cheon, Su Jin Kim, Jieun Lee, Eungu Kang, Jung Hye Byeon, Hee Joon Yu, Young-Lim Shin, Arum Oh, Woo Jin Kim, Mi-Sun Yum, Beom Hee Lee, Baik-Lin Eun
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-15 (2022)
Abstract Background The diagnostic yield of whole-exome sequencing (WES) varies from 30%–50% among patients with mild to severe neurodevelopmental delay (NDD)/intellectual disability (ID). Routine retrospective reanalysis of undiagnosed patients ha
Externí odkaz:
https://doaj.org/article/4cf814bc387f4a96a50b40323f14c258
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100725- (2023)
Externí odkaz:
https://doaj.org/article/17f5cb16572a4c0d9fd837d4655df6e9
Publikováno v:
BioMedical Engineering OnLine, Vol 17, Iss 1, Pp 1-13 (2018)
Abstract Background Diabetes mellitus (DM) is one of the most common diseases worldwide. Uncontrolled and prolonged hyperglycemia can cause diabetic complications, which reduce the quality of life of patients. Diabetic complications are common in DM
Externí odkaz:
https://doaj.org/article/59304939c84946e196ff8f2b0f490e48
Publikováno v:
Journal of Functional Foods, Vol 30, Iss , Pp 303-312 (2017)
Pancreatic cancer is one of the most dangerous cancers. Despite many efforts to improve the prognosis of pancreatic cancer patients, limited progress has been made. In this study, we evaluated an extract of enzymatically hydrolyzed Citrus unshiu peel
Externí odkaz:
https://doaj.org/article/8cba792d45a047a6bd196aec069165bf
Autor:
Heejin Lee, Jun Woo Kim, Dae Kyung Kim, Dong Kyu Choi, Seul Lee, Ji Hoon Yu, Oh-Bin Kwon, Jungsul Lee, Dong-Seok Lee, Jae Ho Kim, Sang-Hyun Min
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2327 (2020)
Drug resistance in epithelial ovarian cancer (EOC) is reportedly attributed to the existence of cancer stem cells (CSC), because in most cancers, CSCs still remain after chemotherapy. To overcome this limitation, novel therapeutic strategies are requ
Externí odkaz:
https://doaj.org/article/2a3a65a9e1f549a0bee6dd35156d60e8
Autor:
Soyoung Chang, Seungjeong Song, Jungsul Lee, Jonghee Yoon, Junseong Park, Sungyoung Choi, Je-Kyun Park, Kyungsun Choi, Chulhee Choi
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88089 (2014)
Loss of contractility and acquisition of an epithelial phenotype of vascular smooth muscle cells (VSMCs) are key events in proliferative vascular pathologies such as atherosclerosis and post-angioplastic restenosis. There is no proper cell culture sy
Externí odkaz:
https://doaj.org/article/6d9a98a6a8e944a5a9265e65715a3e60
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67891 (2013)
A frameshift mutation of ubiquitin called ubiquitin(+1) (UBB(+1)) was found in the aging and Alzheimer's disease brains and thought to be associated with neuronal dysfuction and degeneration. Even though ubiquitylation has been known to regulate vita
Externí odkaz:
https://doaj.org/article/1a5c3b79efb24078bf1d2bf6c91d2c71
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23211 (2011)
Oxidative stresses caused by reactive oxygen species (ROS) can induce rapid depolarization of inner mitochondrial membrane potential and subsequent impairment of oxidative phosphorylation. Damaged mitochondria produce more ROS, especially the superox
Externí odkaz:
https://doaj.org/article/85e998552cf24e68b141ef2ddb634ee5