Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jungseog Kang"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background The development of drug resistance is a major cause of cancer therapy failures. To inhibit drug resistance, multiple drugs are often treated together as a combinatorial therapy. In particular, synergistic drug combinations, which
Externí odkaz:
https://doaj.org/article/6fb831f3c72348b1a938a5687698137d
Publikováno v:
Cell Division, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background The Pax transcription activation domain-interacting protein (PTIP) is a nuclear protein that is an essential component of H3K4 methylation for gene activation in vascular, kidney, B cell, and adipocyte development. Furthermore, it
Externí odkaz:
https://doaj.org/article/8697c02eff57471aa80cf190433ec830
Publikováno v:
Cells, Vol 11, Iss 15, p 2281 (2022)
REGγ, a proteasome activator belonging to the 11S (otherwise known as REG, PA28, or PSME) proteasome activator family, is widely present in many eukaryotes. By binding to the 20S catalytic core particle, REGγ acts as a molecular sieve to selectivel
Externí odkaz:
https://doaj.org/article/6123054057354eb8bf10e6a4d1815d61
Publikováno v:
Cell Cycle. 22:619-632
Accurate spatial and temporal regulation of cell cycle progression is essential for cell proliferation and organismic development. This review demonstrates the role of microspherule protein 58kD, commonly known as MCRS1, as a key cell cycle regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb770f17607a07946e5d9b2966471019
https://doi.org/10.1080/15384101.2022.2145816
https://doi.org/10.1080/15384101.2022.2145816
Autor:
Ying Han, Hongtao Yu, Xiaoai Lu, Wenshu Li, Fengxia Zhang, Jun Liao, Youjun Chu, Hongdan Yang, Piliang Hao, Jungseog Kang, Ching Jung Huang
Publikováno v:
Molecular Biology of the Cell
Accurate partitioning of chromosomes during mitosis is essential for genetic stability and requires the assembly of the dynamic mitotic spindle and proper kinetochore–microtubule attachment. The spindle assembly checkpoint (SAC) monitors the incomp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48d0698a63bb2211301c812c7fb0c5e
https://pubmed.ncbi.nlm.nih.gov/30785839
https://pubmed.ncbi.nlm.nih.gov/30785839
Autor:
Adam D. Coster, Qi Wu, Steven J. Altschuler, Bruce A. Posner, Chien Hsiang Hsu, Jungseog Kang, Lani F. Wu, Shanshan Liu
Publikováno v:
Nature biotechnology
High-content, image-based screens enable the identification of compounds that induce cellular responses similar to those of known drugs but through different chemical structures or targets. A central challenge in designing phenotypic screens is choos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f2bf4c8afae3c08920d8af3aa88ce2
https://doi.org/10.1038/nbt.3419
https://doi.org/10.1038/nbt.3419
Publikováno v:
Molecular Biology of the Cell
Human Shugoshin 1 (Sgo1) protects centromeric sister-chromatid cohesion during mitosis. Heterochromatin protein 1 (HP1) has been proposed to recruit Sgo1 to mitotic centromeres. We show that the molecular interaction targeting HP1 to mitotic centrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49312e2eaa2fcb2c4e80d4847502365
http://europepmc.org/articles/PMC3078076
http://europepmc.org/articles/PMC3078076
Autor:
Wei Qi, Maojun Yang, Diana R. Tomchick, Hongtao Yu, Chao Zhang, Kevan M. Shokat, Mischa Machius, Bing Li, Jungseog Kang
Publikováno v:
Molecular Cell. 32(3):394-405
In mitosis, the spindle checkpoint detects a single unattached kinetochore, inhibits the anaphase-promoting complex or cyclosome (APC/C), and prevents premature sister chromatid separation. The checkpoint kinase Bub1 contributes to checkpoint sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8172b3061f0b801b2d9a8742f3cdbe2
Autor:
Jonathan M. Wong, Stanley Fields, Jungseog Kang, Stefan Westermann, Yuko Nakajima, Ching Shang, Pantea Houshmand, David G. Drubin, Clarence S.M. Chan, Georjana Barnes, Crystal Goodner, Tony R. Hazbun
Publikováno v:
Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications
The mitotic spindle consists of a complex network of proteins that segregates chromosomes in eukaryotes. To strengthen our understanding of the molecular composition, organization, and regulation of the mitotic spindle, we performed a system-wide two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da341159810ada80879b5a1fb7a1a82
https://doi.org/10.1091/mbc.e07-06-0536
https://doi.org/10.1091/mbc.e07-06-0536
Crm1-Mediated Nuclear Export of Cdc14 is Required for the Completion of Cytokinesis in Budding Yeast
Autor:
Cornelia Kurischko, Hongtao Yu, Jungseog Kang, Kenneth D. Belanger, Joshua N. Bembenek, Jesse R. Raab, Francis C. Luca, Bing Li
Publikováno v:
Cell Cycle. 4:961-971
The mitotic exit network (MEN) controls the exit from mitosis in budding yeast. The proline-directed phosphatase, Cdc14p, is a key component of MEN and promotes mitotic exit by activating the degradation of Clb2p and by reversing Cdk-mediated mitotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01579ee5f0a62f0939b939f77611c6a1
https://doi.org/10.4161/cc.4.7.1798
https://doi.org/10.4161/cc.4.7.1798