Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Junghyun L. Suh"'
Autor:
Daniel Bsteh, Shivani Soni, Heather Ogana, Heinz-Josef Lenz, Stephen V. Frye, Stephanie H. Cholensky, Justin M. Rectenwald, Yibo Si, Oliver Bell, Jacqueline L. Norris, Junghyun L. Suh, Lindsey I. James, Tyler M. Weaver, Jessica D. Umana, Dmitri Kireev, Yong-Mi Kim, Bryce Hart, Shannon M. Mumenthaler, Brian Hardy, Cari A. Sagum, Catherine A. Musselman, Roy Lau, Gang Greg Wang, Dongxu Li, Ken H. Pearce, Mark T. Bedford, Carina Pribitzer
Canonical targeting of Polycomb Repressive Complex 1 (PRC1) to repress developmental genes is mediated by cell type-specific, paralogous chromobox (CBX) proteins (CBX2, 4, 6, 7 and 8). Based on their central role in silencing and their misregulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041c17c959746d5da4e46faee689c326
https://doi.org/10.1101/2021.02.23.432388
https://doi.org/10.1101/2021.02.23.432388
Autor:
Kimberly D. Barnash, Fengling Li, Masoud Vedadi, Stephen V. Frye, Dmitri Kireev, Isabelle A. Engelberg, Peter Brown, Cheryl H. Arrowsmith, Tigran M. Abramyan, Junghyun L. Suh, Lindsey I. James
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Many common disease-causing mutations result in loss-of-function (LOF) of the proteins in which they occur. LOF mutations have proven recalcitrant to pharmacologic intervention, presenting a challenge for the development of targeted therapeutics. Pol
Autor:
Stephen V. Frye, Brian D. Strahl, Brian E. Watts, Mark T. Bedford, Eidarus Salah, Junghyun L. Suh, Lindsey I. James, Cari A. Sagum, Yi An, Dmitri Kireev, A. Ali Khan, Jacob I. Stuckey, Alexander T. Adams, Jacqueline Norris-Drouin, Bradley M. Dickson, Stephanie H. Cholensky, S. Mathea, Stefan Knapp
Multivalent binding is an efficient means to enhance the affinity and specificity of chemical probes targeting multidomain proteins in order to study their function and role in disease. While the theory of multivalent binding is straightforward, phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7604d7529092bfe3747ef9f87d4ecf27
https://europepmc.org/articles/PMC5937704/
https://europepmc.org/articles/PMC5937704/
Autor:
Junghyun L. Suh, Alexander T. Adams, Lindsey I. James, Stephen V. Frye, Yi An, Brian D. Strahl, Mark T. Bedford, A. Ali Khan, Jacqueline Norris-Drouin, Brian E. Watts, Dmitri Kireev, Stefan Knapp, Cari A. Sagum, Eidarus Salah, Jacob I. Stuckey, Sebastian Mathea, Bradley M. Dickson, Stephanie H. Cholensky
Publikováno v:
Biochemistry. 57:6806-6806