Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jungeun Yu"'
Publikováno v:
PLoS ONE, Vol 17, Iss 5 (2022)
Notch receptors are determinants of cell fate and function, and play an important role in the regulation of bone development and skeletal remodeling. Lateral Meningocele Syndrome (LMS) is a monogenic disorder associated with NOTCH3 pathogenic variant
Externí odkaz:
https://doaj.org/article/905ef0c0df8b4b55a38bde93f5dca455
Autor:
Hyeongseok Yun, Eui-Soon Park, Seunga Choi, Bongjin Shin, Jungeun Yu, Jiyeon Yu, Dulshara Sachini Amarasekara, Sumi Kim, Nari Lee, Jong-Soon Choi, Yongwon Choi, Jaerang Rho
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008214 (2019)
Postpartum depression is a severe emotional and mental disorder that involves maternal care defects and psychiatric illness. Postpartum depression is closely associated with a combination of physical changes and physiological stress during pregnancy
Externí odkaz:
https://doaj.org/article/ae06f881c6854f739e3c29308df721b7
Autor:
Xi Wang, Brya G Matthews, Jungeun Yu, Sanja Novak, Danka Grcevic, Archana Sanjay, Ivo Kalajzic
Publikováno v:
JBMR Plus, Vol 3, Iss 5, Pp n/a-n/a (2019)
ABSTRACT BMPs are used in various clinical applications to promote bone formation. The limited success of the BMPs in clinical settings and supraphysiological doses required for their effects prompted us to evaluate the influence of other signaling m
Externí odkaz:
https://doaj.org/article/ca0c9b7a2d184a998b9ed0a5c19d928d
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223846 (2019)
Insufficient and delayed fracture healing remain significant public health problems with limited therapeutic options. Phosphoinositide 3-kinase (PI3K) signaling, a major pathway involved in regulation of fracture healing, promotes proliferation, migr
Externí odkaz:
https://doaj.org/article/382406ee55974948b1ca3c0d5d2de0b1
Autor:
Canalis, Ernesto1,2,3 canalis@uchc.edu, Jungeun Yu1,3, Singh, Vijender4, Mocarska, Magda3, Schilling, Lauren3
Publikováno v:
Journal of Biological Chemistry. Dec2023, Vol. 299 Issue 12, p1-13. 13p.
Autor:
Seunga Choi, Hyeongseok Yun, Jungeun Yu, Tae-uk Ha, Hyoeun Jeon, Sumi Kim, Sang Dal Rhee, Bongjin Shin, Jaerang Rho, Eui-Soon Park, Jiyeon Yu, Yongwon Choi, Nari Lee
Publikováno v:
Molecules and Cells
The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) is the master transcriptional regulator in adipogenesis. PPARγ forms a heterodimer with another nuclear receptor, retinoid X receptor (RXR), to form an active transcriptiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2d3e5562188e6fbe8d7d06a8beec37
http://europepmc.org/articles/PMC7854182
http://europepmc.org/articles/PMC7854182
Autor:
Hyoeun Jeon, Jungeun Yu, Jung Me Hwang, Hye-Won Park, Jiyeon Yu, Zee-Won Lee, Taesoo Kim, Jaerang Rho
Publikováno v:
Immune network. 22(5)
Osteoclasts (OCs) are clinically important cells that resorb bone matrix. Accelerated bone destruction by OCs is closely linked to the development of metabolic bone diseases. In this study, we screened novel chemical inhibitors targeting OC different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f599123ec4c96e1872fc756f6182d08b
https://pubmed.ncbi.nlm.nih.gov/36381956
https://pubmed.ncbi.nlm.nih.gov/36381956
Publikováno v:
J Cell Physiol
The present study defines the function of nuclear factor of activated T cells (NFAT)c1 and NFATc2 in osteoblast function in vivo and in vitro. Nfatc1loxP/loxP , Nfatc2loxP/loxP , and Nfatc1loxP/loxP ;Nfatc2loxP/loxP conditional mice were mated with B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ddefdc6655b0a67ec459a49e0f00ff
https://doi.org/10.1002/jcp.29696
https://doi.org/10.1002/jcp.29696
Publikováno v:
Bone
Effective bone resorption by osteoclasts is critical for balanced bone remodeling. We have previously reported that mice harboring a substitution mutation of tyrosine 737 to phenylalanine in the adapter protein Cbl (Cbl Y737F , YF) have increased bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7b35b5e5d59917dd18b8f800441922
https://doi.org/10.1016/j.bone.2019.07.009
https://doi.org/10.1016/j.bone.2019.07.009
Publikováno v:
J Cell Physiol
Lateral meningocele syndrome (LMS), a genetic disorder characterized by meningoceles and skeletal abnormalities, is associated with NOTCH3 mutations. We created a mouse model of LMS (Notch3tm1.1Ecan ) by introducing a tandem termination codon in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dff5d6a4300c6436cf27c16f62710d
https://doi.org/10.1002/jcp.28960
https://doi.org/10.1002/jcp.28960