Zobrazeno 1 - 10
of 915
pro vyhledávání: '"Jung-il Lee"'
Autor:
Nayoung Kim, Sehhoon Park, Areum Jo, Hye Hyeon Eum, Hong Kwan Kim, Kyungjong Lee, Jong Ho Cho, Bo Mi Ku, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Jung-Il Lee, Jung Won Choi, Dasom Jeong, Minsu Na, Huiram Kang, Jeong Yeon Kim, Jung Kyoon Choi, Hae-Ock Lee, Myung-Ju Ahn
Publikováno v:
eLife, Vol 13 (2024)
This study investigates the variability among patients with non-small cell lung cancer (NSCLC) in their responses to immune checkpoint inhibitors (ICIs). Recognizing that patients with advanced-stage NSCLC rarely qualify for surgical interventions, i
Externí odkaz:
https://doaj.org/article/a6cc1516727f4f3688947a807a310c49
Autor:
Nalee Kim, Joongyo Lee, Hyunju Shin, Jungwook Shin, Do-Hyun Nam, Jung-Il Lee, Ho Jun Seol, Doo-Sik Kong, Jung Won Choi, Kyuha Chong, Won Jae Lee, Jong Hee Chang, Seok-Gu Kang, Ju Hyung Moon, Jaeho Cho, Do Hoon Lim, Hong In Yoon
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 47, Iss , Pp 100799- (2024)
Purpose: Severe lymphopenia (SLP) has emerged as a significant prognostic factor in glioblastoma. Intensity-modulated radiation therapy (IMRT)-based radiation therapy (RT) is suggested to minimize the risk of SLP. This study aimed to evaluate SLP inc
Externí odkaz:
https://doaj.org/article/871960f37b6e412586cb43842a46e62a
Autor:
Yoonhee Nam, Harim Koo, Yingxi Yang, Sang Shin, Zhihan Zhu, Donggeon Kim, Hee Jin Cho, Quanhua Mu, Seung Won Choi, Jason K. Sa, Yun Jee Seo, Yejin Kim, Kyoungmin Lee, Jeong-Woo Oh, Yong-Jun Kwon, Woong-Yang Park, Doo-Sik Kong, Ho Jun Seol, Jung-Il Lee, Chul-Kee Park, Hye Won Lee, Yeup Yoon, Jiguang Wang
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Although temozolomide (TMZ) has been used as a standard adjuvant chemotherapeutic agent for primary glioblastoma (GBM), treating isocitrate dehydrogenase wild-type (IDH-wt) cases remains challenging due to intrinsic and acquired d
Externí odkaz:
https://doaj.org/article/99fc4d15a41f4a889cba3961ed437928
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract We investigated the long-term clinical outcomes of patients who underwent multiple courses (≥ 5) of gamma knife radiosurgery (GKRS) due to recurrent brain metastases (BM) from non-small cell lung cancer (NSCLC). Between December 2001 and J
Externí odkaz:
https://doaj.org/article/2cabab22d7734ddf9835bf4ee2652998
Autor:
Jeong-Hwa Kim, Jung-Won Choi, Doo-Sik Kong, Ho Jun Seol, Do-Hyun Nam, Jae-Wook Ryu, Sung-Tae Kim, Yeon-Lim Suh, Jung-Il Lee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract A late-onset treatment-related changes (TRCs), which represent radiographic radiation necrosis (RN), frequently occur after stereotactic radiosurgery (SRS) for brain metastases and often need surgical treatment. This study aimed to validate
Externí odkaz:
https://doaj.org/article/23b0feb8d39c4bdcb325a1ed3b40241c
Publikováno v:
Annals of Child Neurology, Vol 29, Iss 3, Pp 124-133 (2021)
Purpose Hypothalamic hamartoma (HH), a rare congenital disorder, can cause intractable epilepsy and requires optimal surgical treatment. This study analyzed the clinical characteristics of HH and evaluated seizure outcomes and the safety of gamma-kni
Externí odkaz:
https://doaj.org/article/18946c86c266433cb5cefeb48062541e
Autor:
Shin Heon Lee, Chang-Min Ha, Sang Duk Hong, Jung Won Choi, Ho Jun Seol, Do-Hyun Nam, Jung-Il Lee, Doo-Sik Kong
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundDespite recent advances in skull base reconstructive techniques, including the multilayer technique during the last decade, complete reconstruction of grade 3 intraoperative high-flow cerebrospinal fluid (CSF) leak remains challenging. This
Externí odkaz:
https://doaj.org/article/a2a5fd45685d424d8c5e092b6339fd3d
Autor:
Harim Koo, Seung Won Choi, Hee Jin Cho, In‐Hee Lee, Doo‐Sik Kong, Ho Jun Seol, Jung‐Il Lee, Jung‐Won Choi, Jason K. Sa, Do‐Hyun Nam
Publikováno v:
Cancer Medicine, Vol 9, Iss 19, Pp 7352-7359 (2020)
Abstract Glioblastoma (GBM) is the most malignant primary brain tumor in adults with substantial genomic alterations. The median survival is approximately 14.6 months, despite aggressive therapeutic intervention, which comprised of surgical resection
Externí odkaz:
https://doaj.org/article/b389460c6d714d49a5b929ecdab0bbee
Autor:
Jason K. Sa, Nakho Chang, Hye Won Lee, Hee Jin Cho, Michele Ceccarelli, Luigi Cerulo, Jinlong Yin, Sung Soo Kim, Francesca P. Caruso, Mijeong Lee, Donggeon Kim, Young Taek Oh, Yeri Lee, Nam-Gu Her, Byeongkwi Min, Hye-Jin Kim, Da Eun Jeong, Hye-Mi Kim, Hyunho Kim, Seok Chung, Hyun Goo Woo, Jeongwu Lee, Doo-Sik Kong, Ho Jun Seol, Jung-Il Lee, Jinho Kim, Woong-Yang Park, Qianghu Wang, Erik P. Sulman, Amy B. Heimberger, Michael Lim, Jong Bae Park, Antonio Iavarone, Roel G. W. Verhaak, Do-Hyun Nam
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background Glioblastoma (GBM) is a complex disease with extensive molecular and transcriptional heterogeneity. GBM can be subcategorized into four distinct subtypes; tumors that shift towards the mesenchymal phenotype upon recurrence are gen
Externí odkaz:
https://doaj.org/article/e8da640943fc48ff98c50176324f09fa
Autor:
Nayoung Kim, Hong Kwan Kim, Kyungjong Lee, Yourae Hong, Jong Ho Cho, Jung Won Choi, Jung-Il Lee, Yeon-Lim Suh, Bo Mi Ku, Hye Hyeon Eum, Soyean Choi, Yoon-La Choi, Je-Gun Joung, Woong-Yang Park, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Keunchil Park, Myung-Ju Ahn, Hae-Ock Lee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Understanding the mechanisms that lead to lung adenocarcinoma metastasis is important for identifying new therapeutics. Here, the authors document the changes in the transcriptome of human lung adenocarcinoma using single-cell sequencing and link can
Externí odkaz:
https://doaj.org/article/28e39cc8f39944739a58a123f53b6a98