Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jung-hua Steven Kuo"'
Publikováno v:
European Journal of Pharmaceutical Sciences. 101:11-21
Despite the greater potential for clinical applications of autophagic microRNA (miRNA) delivery, the vector-related effects of such delivery on cells have not been fully explored. In this study, autophagic mmu-miR-494-3p (miR-494) in mouse embryonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a9f37f5e3f341ff601d7e4620c46e4
https://doi.org/10.1016/j.ejps.2017.01.031
https://doi.org/10.1016/j.ejps.2017.01.031
Intercellular communication is known to be involved in various stages of tumour development and metastasis through the secretion of extracellular vesicles (EVs) containing messengers such as microRNAs (miRNAs). Therefore, this study explored miRNA pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769a6296f828074b92fb862deef3764b
Publikováno v:
Molecular Pharmaceutics. 11:3002-3008
The molecular mechanisms of autophagy in polyethylenimine (PEI)-treated cells are not well understood because of the use of nonspecific autophagy inhibitors. Here, we applied autophagy-related gene expression analysis to pinpoint the molecular mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19e95ef4260e5980aed70789583c74c
https://doi.org/10.1021/mp500111u
https://doi.org/10.1021/mp500111u
Autor:
José A. Sánchez Alcázar, Sebastiano Andò, Tsolere Arakelian, Guy Berchem, Daniela Bonofiglio, Sandra Morais Cardoso, Stefania Catalano, Patrice Codogno, Mario D. Cordero, David Cotán, Mario de la Mata, Isabel de Lavera, Ana Raquel Esteves, Subramaniam Ganesh, Marc Germain, Cinzia Giordano, Rui Gomes, Elisabet Alcócer Gómez, Maria Gonçalves-Fernandes, Gérald Guillebaud, Eric Hayat, Gu He, Zhaoyue He, Ming-Shiou Jan, Bassam Janji, Rui Kang, Munehiro Kitada, Daisuke Koya, Jung-Hua Steven Kuo, Marilena Lanzino, Wai-Leng Lee, Chia-Wei Lin, Bo Liu, He Liu, Shouqing Luo, Yuting Ma, Juan Garrido Maraver, Sandrine Medves, Takouhie Mgrditchian, Yoshio Ogura, Kan-Fu Oh, Manuel Oropesa-Ávila, Ana Delgado Pavón, Marina Villanueva Paz, Shensi Shen, Diana Filipa Silva, Hans-Uwe Simon, Pankaj Kumar Singh, Daolin Tang, Elodie Viry, Yangchun Xie, Peng-Nian Yew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f269b8de403777f2f6b13a0e398d925
https://doi.org/10.1016/b978-0-12-802937-4.00021-1
https://doi.org/10.1016/b978-0-12-802937-4.00021-1
Cationic polymers have frequently been used as nonviral vectors for delivering nucleic acids. Despite their fairly high transfection activity, the well-known cytotoxicity of cationic polymers remains a key obstacle for their use in clinical applicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62ab32ba56ec769e4e8c9546d93589a2
https://doi.org/10.1016/b978-0-12-802937-4.00006-5
https://doi.org/10.1016/b978-0-12-802937-4.00006-5
Publikováno v:
European Journal of Pharmaceutical Sciences. 47:865-874
Polyethylenimine (PEI) and poly(L-lysine) (PLL), which are cationic polymers used for gene therapy, are known to be cytotoxic, but their molecular mechanisms of cell death are not fully understood. In this study, we provide evidence that PEI and PLL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384386f29f6069522f319564a2c9978b
https://doi.org/10.1016/j.ejps.2012.09.007
https://doi.org/10.1016/j.ejps.2012.09.007
Publikováno v:
Journal of Drug Targeting. 20:515-523
There is increased interest in using cell penetrating peptides such as HIV Tat-derived peptide (Tat) to deliver biologically active cargo to cells. However, little is known about the precise molecular mechanism in cells after the uptake of Tat and af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce5542a278ffa1695777cc244f1ddb3
https://doi.org/10.3109/1061186x.2012.693496
https://doi.org/10.3109/1061186x.2012.693496
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 64:208-215
Tyloxapol is reported to prevent macrophages from reacting to endotoxin. However, the intracellular responses that tyloxapol induces in macrophages are still not fully explored. Hence, the objective of this study was to evaluate the intracellular eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d18c7d38e0f9e439ff143fde17d9bc4
https://doi.org/10.1016/j.colsurfb.2008.01.024
https://doi.org/10.1016/j.colsurfb.2008.01.024
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 64:307-313
Catanionic vesicles are considered a potential alternative to liposomes for drug delivery systems because of their greater stability and lower cost. Before using catanionic vesicles in vivo, their interactions with macrophages must be fully understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4403c3d2594c2b73726e9ad86ed92ef
https://doi.org/10.1016/j.colsurfb.2008.02.006
https://doi.org/10.1016/j.colsurfb.2008.02.006
Publikováno v:
Journal of Controlled Release. 120:51-59
Interest in using poly(propyleneimine) (PPI) dendrimers for biomedical applications is increasing. Before using PPI dendrimers in vivo, their interactions with macrophages must be fully understood because they are primarily removed from circulation b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc127c80c76f6cbda470fa744cada10
https://doi.org/10.1016/j.jconrel.2007.03.019
https://doi.org/10.1016/j.jconrel.2007.03.019