Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Jung-Hyun Cho"'
Autor:
Kyung-Won Min, Myung Hyun Jo, Minseok Song, Ji Won Lee, Min Ji Shim, Kyungmin Kim, Hyun Bong Park, Shinwon Ha, Hyejin Mun, Ahsan Polash, Markus Hafner, Jung-Hyun Cho, Dongsan Kim, Ji-Hoon Jeong, Seungbeom Ko, Sungchul Hohng, Sung-Ung Kang, Je-Hyun Yoon
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-15 (2024)
ABSTRACTAlthough Argonaute (AGO) proteins have been the focus of microRNA (miRNA) studies, we observed AGO-free mature miRNAs directly interacting with RNA-binding proteins, implying the sophisticated nature of fine-tuning gene regulation by miRNAs.
Externí odkaz:
https://doaj.org/article/2031b122a0b248eea1c5236fa50038ff
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 457 (2024)
Enzalutamide (ENZ), marketed under the brand name Xtandi® as a soft capsule, is an androgen receptor signaling inhibitor drug actively used in clinical settings for treating prostate cancer. However, ENZ’s low solubility and bioavailability signif
Externí odkaz:
https://doaj.org/article/4a898b19b06e4e1f9800151b650fc4f4
Autor:
Kyung-Won Min, Kyoung-Min Choi, Hyejin Mun, Seungbeom Ko, Ji Won Lee, Sagum, Cari A., Bedford, Mark T., Young-Kook Kim, Delaney, Joe R., Jung-Hyun Cho, Dawson, Ted M., Dawson, Valina L., Twal, Waleed, Dong-Chan Kim, Panganiban, Clarisse H., Hainan Lang, Xin Zhou, Shin, Seula, Jian Hu, Heise, Tilman
Publikováno v:
Journal of Cell Science; Nov2024, Vol. 137 Issue 21, p1-13, 13p
Autor:
Senyo S. Whyte, Rebekah Karns, Kyung‐Won Min, Jung‐Hyun Cho, Sanghoon Lee, Charissa Lake, Alexander Bondoc, Je‐Hyun Yoon, Soona Shin
Publikováno v:
Cancer Reports, Vol 6, Iss 1, Pp n/a-n/a (2023)
Abstract Background Pediatric hepatocellular carcinoma (HCC) is a group of liver cancers whose mechanisms behind their pathogenesis and progression are poorly understood. Aim We aimed to identify alterations in the expression of miRNAs and their puta
Externí odkaz:
https://doaj.org/article/6bcf8f176bdb4ce09cc9364855d78339
Autor:
Tae-Gyun Woo, Min-Ho Yoon, So-mi Kang, Soyoung Park, Jung-Hyun Cho, Young Jun Hwang, Jinsook Ahn, Hyewon Jang, Yun-Jeong Shin, Eui-Man Jung, Nam-Chul Ha, Bae-Hoon Kim, Yonghoon Kwon, Bum-Joon Park
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
With ELISA-based screening, Woo et al. identify a new small molecule, PRG-A01, which can block the misfolding/aggregation of SOD1 or TDP-43 in a human neuroblastoma cell line. Its use in a mouse model of ALS results in improvement of muscle strength,
Externí odkaz:
https://doaj.org/article/f1e4045faeb04055bfa9700b0679930b
Autor:
So-mi Kang, Min-Ho Yoon, Su-Jin Lee, Jinsook Ahn, Sang Ah Yi, Ki Hong Nam, Soyoung Park, Tae-Gyun Woo, Jung-Hyun Cho, Jaecheol Lee, Nam-Chul Ha, Bum-Joon Park
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Werner syndrome (WRN) is a rare progressive genetic disorder, caused by functional defects in WRN protein and RecQ4L DNA helicase. Acceleration of the aging process is initiated at puberty and the expected life span is approximately the late
Externí odkaz:
https://doaj.org/article/01b8eaca40fd400584abe15784946828
Autor:
So-mi Kang, Min-Ho Yoon, Jinsook Ahn, Ji-Eun Kim, So Young Kim, Seock Yong Kang, Jeongmin Joo, Soyoung Park, Jung-Hyun Cho, Tae-Gyun Woo, Ah-Young Oh, Kyu Jin Chung, So Yon An, Tae Sung Hwang, Soo Yong Lee, Jeong-Su Kim, Nam-Chul Ha, Gyu-Yong Song, Bum-Joon Park
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Kang, Park and colleagues develop and demonstrate the effects of a new drug candidate for treatment of Hutchinson-Gilford progeria syndrome pathologies. Progerinin extends the life span of mice used to model this disease and induces histological and
Externí odkaz:
https://doaj.org/article/f096a2f1eb914af38e3c04e0baf1efeb
Autor:
So‑mi Kang, Min‑Ho Yoon, Su‑Jin Lee, Jinsook Ahn, Sang Ah Yi, Ki Hong Nam, Soyoung Park, Tae‑Gyun Woo, Jung‑Hyun Cho, Jaecheol Lee, Nam‑Chul Ha, Bum‑Joon Park
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/428ebffdc66f4231b713e0d9a95b58d2
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2073 (2022)
The poor aqueous solubility and/or permeability and thereby limited bioavailability largely restricts the pharmaco-therapeutic implications of potent anticancer drugs such as methotrexate (MTX). Furthermore, MTX’s inherently unstable nature makes i
Externí odkaz:
https://doaj.org/article/68269a00f4f14d06ab15c78b73d4551d
Autor:
Bum-Joon Park, Ho-Young Lee, Nam-Chul Ha, Jihwan Hwang, Shin-Deok Hong, Tae-Gyun Woo, Min-Ho Yoon, So-mi Kang, Soyoung Park, Ah-Young Oh, Jung-Hyun Cho
Supplementary Figure S1. Loss of NF2 protects mechanical stress-induced cell death. Supplementary Figure S2. TβR1 is sensor of physical stimulation. Supplementary Figure S3. TβR1 kinase activity is required for RKIP and NF2 suppression. Supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbd2ed81c620843911ec9630d75bc5d
https://doi.org/10.1158/1535-7163.22509123
https://doi.org/10.1158/1535-7163.22509123
