Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jung-Hak Kim"'
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185764 (2017)
Adipocyte differentiation is regulated by intracellular reactive oxygen species (ROS) generation and mitochondrial fission and fusion processes. However, the correlation between intracellular ROS generation and mitochondrial remodeling during adipocy
Externí odkaz:
https://doaj.org/article/81b05c4e97ff483cb71d7923381e2cd6
Autor:
Kyung-Mi Choi, Christopher Y. Ko, Sung-Min An, Seung-Hee Cho, Douglas J. Rowland, Jung Hak Kim, Anna Fasoli, Abhijit J. Chaudhari, Donald M. Bers, John C. Yoon
Publikováno v:
Molecular Metabolism, Vol 69, Iss , Pp 101679- (2023)
Objective: Cold stimuli trigger the conversion of white adipose tissue into beige adipose tissue, which is capable of non-shivering thermogenesis. However, what process drives this activation of thermogenesis in beige fat is not well understood. Here
Externí odkaz:
https://doaj.org/article/d7d3c5460b9a4a8d95a80c26712d06c5
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1156 (2023)
A metastatic brain tumor is the most common type of malignancy in the central nervous system, which is one of the leading causes of death in patients with lung cancer. The purpose of this study is to evaluate the efficacy of a novel treatment for met
Externí odkaz:
https://doaj.org/article/e06a10c6564944a3bf98923a922c5d58
Autor:
Kyung-Mi Choi, Jung Hak Kim, Xiangmudong Kong, Meltem Isik, Jin Zhang, Hee-Woong Lim, John C. Yoon
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110104- (2021)
Summary: Manipulation of energy-dissipating adipocytes has the potential to produce metabolic benefits. To this end, it is valuable to understand the mechanisms controlling the generation and function of thermogenic fat. Here, we identify Letm1 domai
Externí odkaz:
https://doaj.org/article/7e2be8fd649b495baef1316673e8cd7e
Autor:
Kyung-Mi Choi, Sung-Hee Cho, Jung Hak Kim, Ae-Rhee Lilian Kim, Xiangmudong Kong, John C. Yoon
Publikováno v:
Journal of Cystic Fibrosis. 22:132-139
Cystic fibrosis (CF) is characterized by reduced growth and lower body weight, which are multifactorial. CF mouse models lack key disease characteristics that predispose to a negative energy balance, such as pulmonary infections or exocrine pancreati
Autor:
So Hee Kim, Bokyung Kim, Jung Hak Kim, Dong-Hoon Kim, Seung Hoon Lee, Dong-Seok Lee, Hong J. Lee
Publikováno v:
Cells, Vol 10, Iss 8, p 1980 (2021)
Canines are useful in mammalian preclinical studies because they are larger than rodents and share many diseases with humans. Canine fetal fibroblast cells (CFFs) are an easily accessible source of somatic cells. However, they are easily driven to se
Externí odkaz:
https://doaj.org/article/7002162bce424b1889512e1519c063f4
Autor:
Jung Hak Kim, So Young Kim, Bokyung Kim, Sang Rae Lee, Sang Hoon Cha, Dong Seok Lee, Hong Jun Lee
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 321 (2021)
Stroke is a serious, adverse neurological event and the third leading cause of death and disability worldwide. Most strokes are caused by a block in cerebral blood flow, resulting in neurological deficits through the death of brain tissue. Recombinan
Externí odkaz:
https://doaj.org/article/7c247cfc77324fc39415ddcf8a7bbd81
Autor:
So Hee, Kim, Bokyung, Kim, Jung Hak, Kim, Dong-Hoon, Kim, Seung Hoon, Lee, Dong-Seok, Lee, Hong J, Lee
Publikováno v:
Cells
Canines are useful in mammalian preclinical studies because they are larger than rodents and share many diseases with humans. Canine fetal fibroblast cells (CFFs) are an easily accessible source of somatic cells. However, they are easily driven to se
Autor:
Kyung-Mi Choi, Jung Hak Kim, Xiangmudong Kong, Meltem Isik, Jin Zhang, Hee-Woong Lim, John C. Yoon
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110104-(2021)
Summary: Manipulation of energy-dissipating adipocytes has the potential to produce metabolic benefits. To this end, it is valuable to understand the mechanisms controlling the generation and function of thermogenic fat. Here, we identify Letm1 domai
Autor:
Hyun-Shik Lee, Jung-Hak Kim, Joongbae Seong, Dong-Seok Lee, Sang-Rae Lee, Unbin Chae, Sun-Ji Park, Seung-Hoon Lee
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 99:80-90
Insulin signaling is essential for regulating glucose homeostasis. Numerous studies have demonstrated that reactive oxygen species (ROS) affect insulin signaling, and low ROS levels can act as a signal to regulate cellular function. Peroxiredoxins (P