Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jung-Cheng Hsiang"'
Publikováno v:
The Journal of Physical Chemistry Letters. 8:3536-3543
We harness the photophysics of few-atom silver nanoclusters to create the first fluorophores capable of Optically Activated Delayed Fluorescence (OADF). In analogy with thermally activated delayed fluorescence, often resulting from oxygen- or collisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6a6c5b959caa75162f45ebec94ef7e
https://doi.org/10.1021/acs.jpclett.7b01215
https://doi.org/10.1021/acs.jpclett.7b01215
Publikováno v:
The Journal of Physical Chemistry Letters. 7:2496-2501
Excitation of few-atom Ag cluster fluorescence produces significant steady-state dark state populations that can be dynamically optically depopulated with long wavelength co-illumination. Modulating this secondary illumination dynamically repopulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81da15c0759625961f64b547ee147c4
https://doi.org/10.1021/acs.jpclett.6b00940
https://doi.org/10.1021/acs.jpclett.6b00940
Publikováno v:
Accounts of Chemical Research
Conspectus Fluorescence microscopy and detection have become indispensible for understanding organization and dynamics in biological systems. Novel fluorophores with improved brightness, photostability, and biocompatibility continue to fuel further a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b095e2a0ae0425204c098169b4c67dcf
http://europepmc.org/articles/PMC4033652
http://europepmc.org/articles/PMC4033652
Publikováno v:
The Journal of Physical Chemistry A. 117:9501-9509
Optically modulated fluorescence from ∼140 nM Cy5 is visualized when embedded up to 6 mm within skin tissue mimicking phantoms, even in the presence of overwhelming background fluorescence and scatter. Experimental and finite element analysis (FEA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4acd0f06e4e8d321a1b3bcb12d4186
https://doi.org/10.1021/jp312071n
https://doi.org/10.1021/jp312071n
Publikováno v:
ChemPhysChem. 13:1023-1029
Fluorescence modulation offers the opportunity to detect low-concentration fluorophore signals within high background. Applicable from the single-molecule to bulk levels, we demonstrate long-wavelength optical depopulation of dark states that otherwi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4ec4f5a3bc771d5a519c804c9af08d
https://doi.org/10.1002/cphc.201100671
https://doi.org/10.1002/cphc.201100671
Publikováno v:
The Journal of Physical Chemistry B. 114:660-665
Fluorescence intermittency severely limits brightness in both single molecule and bulk fluorescence. Herein, we demonstrate that optical depopulation of organic fluorophore triplet states opens a path to significantly increased sensitivity by simulta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b142a9b7ce171df5401c4220e30c7b13
https://doi.org/10.1021/jp909167j
https://doi.org/10.1021/jp909167j
Autor:
Christopher I. Richards, Yasuko Antoku, Jose Gonzalez, Tom Vosch, Jung-Cheng Hsiang, Robert M. Dickson
Publikováno v:
Proceedings of the National Academy of Sciences. 104:12616-12621
The water-soluble, near-IR-emitting DNA-encapsulated silver nanocluster presented herein exhibits extremely bright and photostable emission on the single-molecule and bulk levels. The photophysics have been elucidated by intensity-dependent correlati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5069dee0db57bdbc660df3c4994d27
https://doi.org/10.1073/pnas.0610677104
https://doi.org/10.1073/pnas.0610677104
Autor:
Robert M. Dickson, Jung-Cheng Hsiang, Eric A. Owens, Chaoyang Fan, Maged Henary, Daniel P. Mahoney
Cyanine dyes are well-known for their bright fluorescence and utility in biological imaging. However, cyanines also readily photoisomerize to produce nonemissive dark states. Co-illumination with a secondary, red-shifted light source on-resonance wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc986cd895b1cdec2356e2b3043e528
https://europepmc.org/articles/PMC4724789/
https://europepmc.org/articles/PMC4724789/
Autor:
Yen-Cheng Chen, Andreas S. Bommarius, Pritha Bagchi, Laren M. Tolbert, Irina Issaeva, Russell B. Vegh, Robert M. Dickson, Christoph J. Fahrni, Bettina Bommarius, Amy E. Jablonski, Jung-Cheng Hsiang
Publikováno v:
Biophysical Journal. 106(2)
Fluorescence microscopy is a widely used non-invasive tool for investigating intracellular structure and processes. Although the palette of fluorescent proteins has revolutionized detection and dynamics in molecular and cellular biology, the limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fce49d581dafc11b203e2c9547c2b4c
Autor:
Laren M. Tolbert, Amy E. Jablonski, Robert M. Dickson, Jung-Cheng Hsiang, Russell B. Vegh, Andreas S. Bommarius, Bettina Bommarius, Yen-Cheng Chen, Kyril M. Solntsev
Publikováno v:
Journal of the American Chemical Society. 135(44)
Blue fluorescent proteins (BFPs) offer visualization of protein location and behavior, but often suffer from high autofluorescent background and poor signal discrimination. Through dual-laser excitation of bright and photoinduced dark states, mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd2bbe8d5f1c995e5e71ca67111eb17
https://pubmed.ncbi.nlm.nih.gov/24099419
https://pubmed.ncbi.nlm.nih.gov/24099419