Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jung Youn Shin"'
Autor:
Samuel Herberg, Daniel Varghai, Daniel S. Alt, Phuong N. Dang, Honghyun Park, Yuxuan Cheng, Jung-Youn Shin, Anna D. Dikina, Joel D. Boerckel, Marsha W. Rolle, Eben Alsberg
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Herberg et al. previously showed functional healing of femoral defects using scaffold-free human mesenchymal stem cell (hMSC) condensates with localized morphogen presentation. In this study, they report the importance of the tubular geometry of MSC
Externí odkaz:
https://doaj.org/article/ca034ebc68764f5a85b780ac8aa721e4
Autor:
Rossana Schipani, Jung-Youn Shin, Aidan McAlinden, Daniel J. Kelly, Pedro J. Díaz-Payno, Daniel Withers, Eben Alsberg, Gráinne M. Cunniffe, Susan E. Critchley, Adam O'Reilly
Publikováno v:
Tissue Engineering Part A. 25:159-171
Successfully treating osteochondral defects involves regenerating both the damaged articular cartilage and the underlying subchondral bone, in addition to the complex interface that separates these tissues. In this study, we demonstrate that a cartil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26654f44c033b96ee5eb894da12e3eb2
https://doi.org/10.1089/ten.tea.2018.0046
https://doi.org/10.1089/ten.tea.2018.0046
Autor:
Honghyun Park, Yuxuan Cheng, Joel D. Boerckel, Samuel Herberg, Jung-Youn Shin, Eben Alsberg, Daniel Varghai, Phuong N. Dang, Anna D. Dikina, Daniel S. Alt, Marsha W. Rolle
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Biomimetic bone tissue engineering strategies partially recapitulate development. We recently showed functional restoration of femoral defects using scaffold-free human mesenchymal stem cell (hMSC) condensates featuring localized morphogen presentati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898e3b4ec73a213e9fd38e45fe0c0494
Autor:
Eben Alsberg, Daniel J. Kelly, Lieke H. A. van Dommelen, Jessica Nulty, Jung-Youn Shin, Fiona E. Freeman, David C. Browe, Pierluca Pitacco
Publikováno v:
Bio-Protocol, 11, 21
Bio-Protocol, 11
Bio Protoc
Bio-Protocol, 11
Bio Protoc
The local delivery of growth factors such as BMP-2 is a well-established strategy for the repair of bone defects. The limitations of such approaches clinically are well documented and can be linked to the need for supraphysiological doses and poor sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36885520373d9dbe6a7129546d72f6f
https://repository.ubn.ru.nl/handle/2066/244786
https://repository.ubn.ru.nl/handle/2066/244786
Autor:
Daniel J. Kelly, Lieke H. A. van Dommelen, Eben Alsberg, Jessica Nulty, Pierluca Pitacco, Fiona E. Freeman, Jung-Youn Shin, David C. Browe
Publikováno v:
Science Advances
Science Advances, 6
Science Advances, 6, 33
Science Advances, 6
Science Advances, 6, 33
Spatiotemporal delivery of VEGF and BMP-2 from 3D bioprinted implants enhances angiogenesis and subsequent bone regeneration.
Therapeutic growth factor delivery typically requires supraphysiological dosages, which can cause undesirable off-targe
Therapeutic growth factor delivery typically requires supraphysiological dosages, which can cause undesirable off-targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d699858bc89b21aafa85a95881550a4
Autor:
Oju Jeon, Hong Hyun Park, Jung Youn Shin, Eben Alsberg, Robyn Marks, Mitchell Hopkins, Tae-Hee Kim
Publikováno v:
Chemistry of Materials. 29:8425-8432
Although hydrogels are extensively investigated as biomaterials due to their ability to mimic cellular microenvironments, they are often limited by their poor physical properties in response to mechanical loads, including weak gel strength, brittlene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2968dcadc249cb274b756a1874a49847
https://doi.org/10.1021/acs.chemmater.7b02995
https://doi.org/10.1021/acs.chemmater.7b02995
Autor:
Jung-Youn Shin, Jong-Mo Ahn
Publikováno v:
Journal of Oral Medicine and Pain. 42:35-43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d73cc02eb901d74f3024e7a8903e827f
https://doi.org/10.14476/jomp.2017.42.2.35
https://doi.org/10.14476/jomp.2017.42.2.35
Autor:
Noo Li Jeon, Pilnam Kim, Byung Soo Kim, Hoon Eui Jeong, Min Sung Kim, Daeshik Kang, Sang Moon Kim, Hong Nam Kim, Kyung-Jin Jang, Kahp-Yang Suh, Ilkyoo Koh, Segeun Jang, Yoonmi Hong, Jung-Youn Shin
Publikováno v:
ACS Nano. 11:730-741
We present a method to induce cell directional behavior using slanted nanocilia arrays. NIH-3T3 fibroblasts demonstrated bidirectional polarization in a rectangular arrangement on vertical nanocilia arrays and exhibited a transition from a bidirectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3015f09ed675a0441d6b3851755612
https://doi.org/10.1021/acsnano.6b07134
https://doi.org/10.1021/acsnano.6b07134
Autor:
Ming Kong, Wujin Sun, KangJu Lee, Amr A. Abdeen, Su Ryon Shin, Somali Chaterji, Yu Bin Lee, Han-Jun Kim, Ha Neul Lee, Sang Jin Lee, Praveen Bandaru, Oju Jeon, Jung-Youn Shin, Daniel S. Alt, Ali Khademhosseini, Eben Alsberg, Junmin Lee
Publikováno v:
Science Advances
Multicomponent biomaterials using a high-throughput system regulate hyaline or hypertrophic chondrogenesis of hMSCs.
Despite great progress in biomaterial design strategies for replacing damaged articular cartilage, prevention of stem cell-deriv
Despite great progress in biomaterial design strategies for replacing damaged articular cartilage, prevention of stem cell-deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fa8639d0b1e04e044418ef7e716a00
https://pubmed.ncbi.nlm.nih.gov/32494742
https://pubmed.ncbi.nlm.nih.gov/32494742
Autor:
Daniel S. Alt, Honghyun Park, Yuxuan Cheng, Joel D. Boerckel, P. C. Wong, Felicia He, Anna D. Dikina, Samuel Herberg, Yu Bin Lee, Phuong N. Dang, Alexandra McMillan, Rui Tang, James H. Dawahare, Eben Alsberg, Daniel Varghai, Kentaro Umemori, Anna M. McDermott, Jung Youn Shin
Publikováno v:
Science Advances
Mesenchymal condensations promote defect repair by mimicking cellular, morphogenetic, and mechanical aspects of bone development.
Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell c
Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60f8942e445a052dfb5cdf82e165d23
https://doi.org/10.1126/sciadv.aax2476
https://doi.org/10.1126/sciadv.aax2476