Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Jung Yaw Lin"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126725 (2015)
Inhibition of VEGFR2 activity has been proposed as an important strategy for the clinical treatment of hepatocellular carcinoma (HCC). In this study, we identified corosolic acid (CA), which exists in the root of Actinidia chinensis, as having a sign
Externí odkaz:
https://doaj.org/article/29c13cfa3ba942c8ac010cbe76206631
Publikováno v:
The American Journal of Chinese Medicine. 47:1459-1481
To evaluate the therapeutic effects of Chinese herbal medicine (CHM) for Alzheimer’s disease (AD), we evaluated five CHMs in oligomeric A[Formula: see text]-treated mouse primary hippocampal neuronal cultures. The aqueous extract from the root of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbceaf20bef613162ea5ab499178bad
https://doi.org/10.1142/s0192415x19500757
https://doi.org/10.1142/s0192415x19500757
Autor:
Te-Hsien Lin, Wan-Ling Chen, Chih-Ying Chao, Chih-Hsin Lin, Jung Yaw Lin, Chiung-Mei Chen, Guey Jen Lee-Chen, Mu-Chun Chiang, Hsuan-Yuan Lin, Mei-Ling Cheng, Yih-Ru Wu, Chia-Ning Chang, I-Cheng Chen
Publikováno v:
The American Journal of Chinese Medicine. 47:63-95
Nine autosomal dominant spinocerebellar ataxias (SCAs) are caused by an abnormal expansion of CAG trinucleotide repeats that encodes a polyglutamine (polyQ) tract within different genes. Accumulation of aggregated mutant proteins is a common feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ff2d8578b8746bee8e2446bfb81db1
https://doi.org/10.1142/s0192415x19500046
https://doi.org/10.1142/s0192415x19500046
Autor:
Li-Ching Lee, Chiung-Mei Chen, Hao-Chun Wang, Hsiao-Han Hsieh, I-Sheng Chiu, Ming-Tsan Su, Hsiu-Mei Hsieh-Li, Chung-Hsin Wu, Guan-Chiun Lee, Guey-Jen Lee-Chen, Jung-Yaw Lin
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35302 (2012)
Spinocerebellar ataxia 17 (SCA17) is caused by expansion of the polyglutamine (polyQ) tract in human TATA-box binding protein (TBP) that is ubiquitously expressed in both central nervous system and peripheral tissues. The spectrum of SCA17 clinical p
Externí odkaz:
https://doaj.org/article/9c8b513e7652499da69408c1cae0f26b
Autor:
Bai Jiun Kuo, Yu Chih Lo, Chao Yu Yang, Wen Pin Kao, Su Chang Lin, Tsung Wei Su, Jung Yaw Lin, Shan Meng Lin
Publikováno v:
Structure. 25:407-420
Death domain (DD)-fold assemblies play a crucial role in regulating the signaling to cell survival or death. Here we report the crystal structure of the caspase recruitment domain (CARD)-CARD disk of the human apoptosome. The structure surprisingly r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d157ba0ce0f80d25362ae400beaa065
https://doi.org/10.1016/j.str.2016.12.019
https://doi.org/10.1016/j.str.2016.12.019
Autor:
Guey Jen Lee-Chen, Mina Mesri, Hsuan Yuan Lin, Te Hsien Lin, Chiung Mei Chen, Shin Ying Lee, Jung Yaw Lin, Ya Jen Chiu, Kuo-Hsuan Chang, Chi Mei Lee
Publikováno v:
The American journal of Chinese medicine.
Amyloid [Formula: see text] (A[Formula: see text]) plays a major role in the pathogenesis of Alzheimer’s disease (AD). The accumulation of misfolded A[Formula: see text] causes oxidative and inflammatory damage leading to apoptotic cell death. Chin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad83bc00a482945785a641b68d4db86
https://pubmed.ncbi.nlm.nih.gov/30284464
https://pubmed.ncbi.nlm.nih.gov/30284464
Autor:
Yui Ping Weng, Der Yen Lee, Chao-Jung Chen, Ching Liang Hsieh, Yang Chang Wu, Jung-Yaw Lin, Yu Huei Liu, Hsin Ying Tsai
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 46
Background Pancreatic cancer (PC) remains the leading cause of cancer mortality, with limited therapeutic targets, and alterations in endoplasmic reticulum (ER)-related proteostasis may be a potential target for therapy. The root bark of Paeonia suff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39ad64f1dea5453e1cc6fd94d2b78e9
https://pubmed.ncbi.nlm.nih.gov/30097117
https://pubmed.ncbi.nlm.nih.gov/30097117
Autor:
Yui-Ping Weng, Yu-Huei Liu, Sai-Wen Tang, Chi-Jung Liang, Jung-Yaw Lin, Chung-Yu Ku, Hsuan-Yuan Lin, Chao-Jung Chen
Publikováno v:
Scientific Reports
Hepatocellular carcinoma (HCC) remains the leading cause of cancer mortality with limited therapeutic targets. The endoplasmic reticulum (ER) plays a pivotal role in maintaining proteostasis in normal cells. However, alterations in proteostasis are o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ab23c721b66410cf3b9e526220b21b
https://doi.org/10.1038/srep41437
https://doi.org/10.1038/srep41437
Autor:
Chiung Mei Chen, Chih Ying Chao, Yi-Chun Chen, Te Hsien Lin, Li Ching Lee, Yih Ru Wu, Yi Ci Wu, Kuo-Hsuan Chang, Wan Ling Chen, Jung Yaw Lin, Guey Jen Lee-Chen
Publikováno v:
Neuropharmacology. 81:166-175
Spinocerebellar ataxias (SCAs), caused by expanded CAG repeats encoding a long polyglutamine (polyQ) tract in the respective proteins, are characterized by the accumulation of intranuclear and cytoplasmic misfolded polyQ aggregation that leads to cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b94b7bf0a00180d43719c1c57fabe2e
https://doi.org/10.1016/j.neuropharm.2014.01.032
https://doi.org/10.1016/j.neuropharm.2014.01.032
Autor:
Sai-Wen Tang1, Jung-Yaw Lin1 linjy@ntu.edu.tw
Publikováno v:
Journal of Oncology. 2012, p1-15. 15p.