Výsledky vyhledávání - "Jung Shin Lee"

Akademický článek

Swd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6

Autor: Junsoo Oh, Shinae Park, Jueun Kim, Soojin Yeom, Ji Min Lee, Eun-Jin Lee, Yong-Joon Cho, Jung-Shin Lee

Publikováno v: BMC Biology, Vol 22, Iss 1, Pp 1-12 (2024)

Abstract Background Histone H3K4 tri-methylation (H3K4me3) catalyzed by Set1/COMPASS, is a prominent epigenetic mark found in promoter-proximal regions of actively transcribed genes. H3K4me3 relies on prior monoubiquitination at the histone H2B (H2Bu

Externí odkaz: https://doaj.org/article/a975e1dfbf7f4e6fa9e9e1105286fc73

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Ctr9 promotes virulence of Candida albicans by regulating methionine metabolism

Autor: Jiyeon Park, Shinae Park, Jueun Kim, Yong-Joon Cho, Jung-Shin Lee

Publikováno v: Virulence, Vol 15, Iss 1 (2024)

Candida albicans, a part of normal flora, is an opportunistic fungal pathogen and causes severe health issues in immunocompromised patients. Its pathogenicity is intricately linked to the transcriptional regulation of its metabolic pathways. Paf1 com

Externí odkaz: https://doaj.org/article/44a8eba1d9114df2a41467d046d4bc35

Zobrazit plný text záznamu

Akademický článek

YM155 induces EGFR suppression in pancreatic cancer cells.

Autor: Young-Soon Na, Soo-Jin Yang, Seung-Mi Kim, Kyung-Ah Jung, Jai-Hee Moon, Jae-Sik Shin, Dok Hyun Yoon, Yong Sang Hong, Min-Hee Ryu, Jae-Lyun Lee, Jung Shin Lee, Tae Won Kim

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38625 (2012)

YM155, which inhibits the anti-apoptotic protein survivin, is known to exert anti-tumor effects in various cancers, including prostate and lung cancer. However, there are few reports describing the inhibitory effect of YM155 on human pancreatic cance

Externí odkaz: https://doaj.org/article/a1957ac15eb54c98bc49d1cc7e840ca5

Zobrazit plný text záznamu

Akademický článek

The regional sequestration of heterochromatin structural proteins is critical to form and maintain silent chromatin

Autor: Junsoo Oh, Soojin Yeom, Jiyeon Park, Jung-Shin Lee

Publikováno v: Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-13 (2022)

Abstract Budding yeast Saccharomyces cerevisiae and fission yeast Schizosaccharomyces pombe are good models for heterochromatin study. In S. pombe, H3K9 methylation and Swi6, an ortholog of mammalian HP1, lead to heterochromatin formation. However, S

Externí odkaz: https://doaj.org/article/7d243d5012744f408aa1dbe464e82285

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Set1-mediated H3K4 methylation is required for Candida albicans virulence by regulating intracellular level of reactive oxygen species

Autor: Jueun Kim, Shinae Park, So Hee Kwon, Eun-Jin Lee, Jung-Shin Lee

Publikováno v: Virulence, Vol 12, Iss 1, Pp 2648-2658 (2021)

Candida albicans is an opportunistic human fungal pathogen that exists in normal flora but can cause infection in immunocompromised individuals. The transition to pathogenic C. albicans requires a change of various gene expressions. Because histone-m

Externí odkaz: https://doaj.org/article/665a9202b596483fb1b32a3bcf82ed99

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg 2+ Transporter in Salmonella Typhimurium

Autor: Eunna Choi, Yoontak Han, Shinae Park, Hyojeong Koo, Jung-Shin Lee, Eun-Jin Lee

Publikováno v: mBio, Vol 12, Iss 2 (2021)

Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure. Therefore, to initiate protein synthesis, the mRNA secondary structure must be unfolded to al

Externí odkaz: https://doaj.org/article/3faa8c09d1b3491982297d5f67dec44a

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání