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Akademický článek

Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.

Autor: Philip J Smaldino, Eric D Routh, Jung H Kim, Banabihari Giri, Steven D Creacy, Roy R Hantgan, Steven A Akman, James P Vaughn

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0132668 (2015)

Ends of human chromosomes consist of the six nucleotide repeat d[pTTAGGG]n known as telomeric DNA, which protects chromosomes. We have previously shown that the DHX36 gene product, G4 Resolvase 1 (G4R1), binds parallel G-quadruplex (G4) DNA with an u

Externí odkaz: https://doaj.org/article/a197ea1e19fe44bc874be96b8aff12ca

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Akademický článek

The Global Turn in Nationalism: The USA as a Battleground for Hinduism and Hindu Nationalism

Autor: Sophie-Jung H. Kim

Publikováno v: Religions, Vol 14, Iss 10, p 1265 (2023)

Hindu nationalism operates on a global scale today. Evinced by the transnational networks of the Sangh Parivar and the replication of strategies such as amending textbooks and patriotic rewriting of history, politics and discourse of Hindu nationalis

Externí odkaz: https://doaj.org/article/150d5efac83645cabcd4bb9a91c87a4a

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Akademický článek

Use of a double-wire woven uncovered nitinol stent for the treatment of refractory tracheal collapse in a dog: a case report

Autor: H.Y. Yoon, J.W. Choi, Ji H. Kim, Jung H. Kim

Publikováno v: Veterinární Medicína, Vol 62, Iss 2, Pp 98-104 (2017)

A 2.7 kg, 11-year-old, castrated male Maltese dog was presented for evaluation of a 2-year history of intractable coughing, dyspnoea and cyanosis. A diagnosis of tracheal collapse with myxomatous mitral valve disease was made on the basis of inspirat

Externí odkaz: https://doaj.org/article/756f6fa588a847f988d0b71b4d8e5cdd

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Data from PD-L1 Expression in Melanocytic Lesions Does Not Correlate with the BRAF V600E Mutation

Autor: Janis M. Taube, Drew M. Pardoll, Suzanne L Topalian, Hao Wang, Brandon S. Luber, Shuming Chen, Katie Beierl, Jung H. Kim, Haiying Xu, Ming-Tseh Lin, James R. Eshleman, Robert A. Anders, Nemanja Rodić

PD-L1 expression in melanoma correlates with response to PD-1 pathway–blocking antibodies. Aberrant tumor-cell PD-L1 expression may be oncogene driven and/or induced by IFNγ. Melanomas express PD-L1 in association with tumor-infiltrating lymphocyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1645bf4a9692b669078c6c47ef8a5bd4
https://doi.org/10.1158/2326-6066.c.6548855

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Data from Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti–PD-1 Therapy

Autor: Robert A. Anders, Suzanne L. Topalian, Drew M. Pardoll, Lieping Chen, Jung H. Kim, Xiaoyu Pan, Haiying Xu, Julie R. Brahmer, Alison Klein, Janis M. Taube

Purpose: Immunomodulatory drugs differ in mechanism-of-action from directly cytotoxic cancer therapies. Identifying factors predicting clinical response could guide patient selection and therapeutic optimization.Experimental Design: Patients (N = 41)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e22b6c77f421ef2ba594268daeaaaf
https://doi.org/10.1158/1078-0432.c.6524486.v1

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