Zobrazeno 1 - 10
of 333
pro vyhledávání: '"Jung Hun Oh"'
Autor:
Rena Elkin, Jung Hun Oh, Filemon Dela Cruz, Larry Norton, Joseph O. Deasy, Andrew L. Kung, Allen R. Tannenbaum
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Network properties account for the complex relationship between genes, making it easier to identify complex patterns in their interactions. In this work, we leveraged these network properties for dual purposes. First, we clustered pediatric
Externí odkaz:
https://doaj.org/article/1a3a594da4ab4acdaeb47f73b4300bb7
Autor:
Xiaohui Sun, Anne S. Reiner, Anh Phong Tran, Gordon P. Watt, Jung Hun Oh, Lene Mellemkjær, Charles F. Lynch, Julia A. Knight, Esther M. John, Kathleen E. Malone, Xiaolin Liang, Meghan Woods, Andriy Derkach, Patrick Concannon, Jonine L. Bernstein, Xiang Shu
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-7 (2024)
Abstract Background Contralateral breast cancer (CBC) is the most common second primary cancer diagnosed in breast cancer survivors, yet the understanding of the genetic susceptibility of CBC, particularly with respect to common variants, remains inc
Externí odkaz:
https://doaj.org/article/c326165dc5464d9caba6fbd5ced243de
Autor:
Anish K. Simhal, Kylee H. Maclachlan, Rena Elkin, Jiening Zhu, Larry Norton, Joseph O. Deasy, Jung Hun Oh, Saad Z. Usmani, Allen Tannenbaum
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The plasma cell cancer multiple myeloma (MM) varies significantly in genomic characteristics, response to therapy, and long-term prognosis. To investigate global interactions in MM, we combined a known protein interaction network with a larg
Externí odkaz:
https://doaj.org/article/8ac2e5a5738b4c569addc774c5791482
Autor:
Wookjin Choi, Chia-Ju Liu, Sadegh Riyahi Alam, Jung Hun Oh, Raj Vaghjiani, John Humm, Wolfgang Weber, Prasad S. Adusumilli, Joseph O. Deasy, Wei Lu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5601-5608 (2023)
Lung adenocarcinoma (ADC) is the most common non-small cell lung cancer. Surgical resection is the primary treatment for early-stage lung ADC while lung-sparing surgery is an alternative for non-aggressive cases. Identifying histopathologic subtypes
Externí odkaz:
https://doaj.org/article/ccc7c9ef4f244867a22477348bf766b5
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Drug-induced liver injury (DILI) is an adverse hepatic drug reaction that can potentially lead to life-threatening liver failure. Previously published work in the scientific literature on DILI has provided valuable insights for the understanding of h
Externí odkaz:
https://doaj.org/article/aec75b2a07454e25a84ad8f4b91e0c12
Autor:
Rena Elkin, Jung Hun Oh, Ying L. Liu, Pier Selenica, Britta Weigelt, Jorge S. Reis-Filho, Dmitriy Zamarin, Joseph O. Deasy, Larry Norton, Arnold J. Levine, Allen R. Tannenbaum
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Network analysis methods can potentially quantify cancer aberrations in gene networks without introducing fitted parameters or variable selection. A new network curvature-based method is introduced to provide an integrated measure of variabi
Externí odkaz:
https://doaj.org/article/14677a3e0f704e37a93284a2df2fb8ea
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Background Coronavirus disease 2019 (COVID-19) is a global public health concern. Recently, a genome-wide association study (GWAS) was performed with participants recruited from Italy and Spain by an international consortium group. Methods S
Externí odkaz:
https://doaj.org/article/1d76d07640694a3ca928d24b69eed13e
Publikováno v:
IEEE Access, Vol 8, Pp 209224-209231 (2020)
Unbalanced optimal mass transport (OMT) seeks to remove the conservation of mass constraint by adding a source term to the standard continuity equation in the Benamou-Brenier formulation of OMT. In this study, we show how the unbalanced case fits int
Externí odkaz:
https://doaj.org/article/17aa3c5d971b41fe9ce109f2f22e213d
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
In this paper, we present a network-based clustering method, called vector Wasserstein clustering (vWCluster), based on the vector-valued Wasserstein distance derived from optimal mass transport (OMT) theory. This approach allows for the natural inte
Externí odkaz:
https://doaj.org/article/5bb18def619e41229038fe6c6cad090a
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S10, Pp 1-13 (2019)
Abstract Background Understanding the complex biological mechanisms of cancer patient survival using genomic and clinical data is vital, not only to develop new treatments for patients, but also to improve survival prediction. However, highly nonline
Externí odkaz:
https://doaj.org/article/30aecae4d42c4b49a2aea6df3e654e04