Zobrazeno 1 - 10
of 526
pro vyhledávání: '"Jung‐Yun Lee"'
Autor:
Byungsoo Ahn, Damin Moon, Hyun-Soo Kim, Chung Lee, Nam Hoon Cho, Heung-Kook Choi, Dongmin Kim, Jung-Yun Lee, Eun Ji Nam, Dongju Won, Hee Jung An, Sun Young Kwon, Su-Jin Shin, Hye Ra Jung, Dohee Kwon, Heejung Park, Milim Kim, Yoon Jin Cha, Hyunjin Park, Yangkyu Lee, Songmi Noh, Yong-Moon Lee, Sung-Eun Choi, Ji Min Kim, Sun Hee Sung, Eunhyang Park
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Platinum-based chemotherapy is the cornerstone treatment for female high-grade serous ovarian carcinoma (HGSOC), but choosing an appropriate treatment for patients hinges on their responsiveness to it. Currently, no available biomarkers can
Externí odkaz:
https://doaj.org/article/4942df33baf24489bbfb6bc5ad4292e7
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Human epidermal growth factor receptor-2 (HER2)-targeting drugs are increasingly being incorporated into therapeutic paradigms for non-breast cancers, yet studies on HER2 expression in ovarian cancer (OC) are inadequate. Here, we studied the
Externí odkaz:
https://doaj.org/article/c1ea68d0727543d19019f0aabc197b49
Autor:
Kyeonghui Kim, Hyemin Kim, Inkyung Shin, Seung-Jae Noh, Jeong Yeon Kim, Koung Jin Suh, Yoo-Na Kim, Jung-Yun Lee, Dae-Yeon Cho, Se Hyun Kim, Jee Hyun Kim, Se-Hoon Lee, Jung Kyoon Choi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Genomic hypomethylation has recently been identified as a determinant of therapeutic responses to immune checkpoint blockade (ICB). However, it remains unclear whether this approach can be applied to cell-free DNA (cfDNA) and whether it can
Externí odkaz:
https://doaj.org/article/f0e7c54e132c444d87710a6b913a3720
Autor:
Yoo-Na Kim, Kyeongmin Kim, Je-Gun Joung, Sang Wun Kim, Sunghoon Kim, Jung-Yun Lee, Eunhyang Park
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveEffective functional biomarkers that can be readily used in clinical practice to predict poly(ADP-ribose) polymerase inhibitor (PARPi) sensitivity are lacking. With the widespread adoption of PARPi maintenance therapy in ovarian cancer, part
Externí odkaz:
https://doaj.org/article/9ca2343756c248a9a61b32f43e008940
Autor:
Chel Hun Choi, Jeong-Won Lee, Duk-Soo Bae, Eun-Suk Kang, Duck Cho, Yong-Man Kim, Kidong Kim, Jae-Weon Kim, Hee Seung Kim, Young-Tae Kim, Jung-Yun Lee, Myong Cheol Lim, Taegwon Oh, Boyeong Song, Insu Jeon, Myunghwan Park, Wu Hyun Kim, Chang-Yuil Kang, Byoung-Gie Kim
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundBVAC-C, a B cell– and monocyte-based immunotherapeutic vaccine transfected with recombinant HPV E6/E7, was well tolerated in HPV–positive recurrent cervical carcinoma patients in a phase I study. This phase IIa study investigates the an
Externí odkaz:
https://doaj.org/article/25f6fbb234fe45fb87de005ce22849a5
Autor:
Taehoon Kim, Hyeonseob Lim, Soyeong Jun, Junsik Park, Dongin Lee, Ji Hyun Lee, Jung-Yun Lee, Duhee Bang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Gynecologic cancer, including ovarian cancer and endometrial cancer, is characterized by morphological and molecular heterogeneity. Germline and somatic testing are available for patients to screen for pathogenic variants in genes such as BR
Externí odkaz:
https://doaj.org/article/39cdf08c2df14fa9a9fbf090e1b92d81
Autor:
Bo Seong Yun, Eun Hye Park, Johyun Ha, Jung-Yun Lee, Keun Ho Lee, Taek Sang Lee, Kyung Ju Lee, Young Ju Kim, Kyu-Won Jung, Ju-Won Roh
Publikováno v:
Obstetrics & Gynecology Science, Vol 66, Iss 6, Pp 545-561 (2023)
Objective To investigate the incidence, trends, and survival rates of all gynecologic cancers using the Korea Central Cancer Registry (KCCR) database from 1999–2019. Methods Gynecologic cancer data were obtained from the KCCR database between 1999
Externí odkaz:
https://doaj.org/article/d5282bd6cce14ef095774f25fb8f2d51
Autor:
Yong Bae Kim, Hwa Kyung Byun, Chan Woo Wee, Hojin Kim, Seyoung Kim, Gowoon Yang, Jina Kim, Sang Joon Park, Jung-Yun Lee
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Efforts have been made to investigate the role of salvage radiotherapy (RT) in treating recurrent ovarian cancer (ROC). Stereotactic ablative radiation therapy (SABR) is a state-of-the-art therapy that uses intensity modulation to
Externí odkaz:
https://doaj.org/article/47fdf4fb1f1c446196ad90194e135696
Autor:
Yoo-Na Kim, Boram Park, Jae Weon Kim, Byoung Gie Kim, Sang Wun Kim, Hee Seung Kim, Chel Hun Choi, Myong Cheol Lim, Natalie YL Ngoi, David SP Tan, Jung-Yun Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract In this multicenter, open-label, single-arm, Phase II study with Simon two-stage optimum design (NCT04361370), we investigate the efficacy and safety of triplet maintenance (olaparib, pembrolizumab, bevacizumab) in patients with platinum-sen
Externí odkaz:
https://doaj.org/article/1de04bd62c64433c9bfbae88ccacfbad
Autor:
Ki Eun Seon, Yong Jae Lee, Jung-Yun Lee, Eun Ji Nam, Sunghoon Kim, Young Tae Kim, Sang Wun Kim
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The number of studies comparing robotic systems in endometrial cancer staging is limited. This retrospective study analyzed the medical records of 42 consecutive endometrial cancer patients, who underwent robotic staging using the da Vinci S
Externí odkaz:
https://doaj.org/article/ce3b979baa704f87b7f2a11342aaf30b