Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Jung‐Chen Su"'
Autor:
Chia-Chun Tung, Shang-Che Kuo, Chia-Ling Yang, Jhong-He Yu, Chia-En Huang, Pin-Chien Liou, Ying-Hsuan Sun, Peng Shuai, Jung-Chen Su, Chuan Ku, Ying-Chung Jimmy Lin
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-37 (2023)
Abstract Background Xylem, the most abundant tissue on Earth, is responsible for lateral growth in plants. Typical xylem has a radial system composed of ray parenchyma cells and an axial system of fusiform cells. In most angiosperms, fusiform cells c
Externí odkaz:
https://doaj.org/article/54b1e7b82bd5433ea4b32cd369d93e0e
Autor:
Hsing‐I Tseng, Yi‐Siang Zeng, Ying‐Chung Jimmy Lin, Jui‐Wen Huang, Chih‐Lung Lin, Meng‐Hsuan Lee, Fan‐Wei Yang, Te‐Ping Fang, Ai‐Chung Mar, Jung‐Chen Su
Publikováno v:
Molecular Oncology, Vol 16, Iss 11, Pp 2274-2294 (2022)
Hepatocellular carcinoma (HCC) is characterized by rapid growth, early vascular invasion, and high metastasis. Currently available US Food and Drug Administration (FDA)‐approved drugs show low therapeutic efficacy, limiting HCC treatment to chemoth
Externí odkaz:
https://doaj.org/article/cd433a0662f84954a5dfbfb4086997c1
Autor:
Ni-Chiao Tsai, Tzu-Shu Hsu, Shang-Che Kuo, Chung-Ting Kao, Tzu-Huan Hung, Da-Gin Lin, Chung-Shu Yeh, Chia-Chen Chu, Jeng-Shane Lin, Hsin-Hung Lin, Chia-Ying Ko, Tien-Hsien Chang, Jung-Chen Su, Ying-Chung Jimmy Lin
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-21 (2021)
Abstract Background Yeast one-hybrid (Y1H) is a common technique for identifying DNA-protein interactions, and robotic platforms have been developed for high-throughput analyses to unravel the gene regulatory networks in many organisms. Use of these
Externí odkaz:
https://doaj.org/article/40a972162ee34080a4a90c961e67091d
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1248-1255 (2018)
The unregulated activation of STAT3 has been demonstrated to occur in many cancers and enhances tumour growth, migration, and invasion. Stimulation by cytokines, growth factors, and hormones triggers this activation by phosphorylating STAT3 at tyrosi
Externí odkaz:
https://doaj.org/article/d93e2dede48b4bd1b1f0b681144666ba
Autor:
Jung-Chen Su, Ping-Hui Tseng, Szu-Hsien Wu, Cheng-Yi Hsu, Wei-Tien Tai, Yong-Shi Li, I-Ting Chen, Chun-Yu Liu, Kuen-Feng Chen, Chung-Wai Shiau
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 7, Pp 595-605 (2014)
Hepatocellular carcinoma is the fifth most common solid cancer worldwide. Sorafenib, a small multikinase inhibitor, is the only approved therapy for advanced HCC. The clinical benefit of sorafenib is offset by the acquisition of sorafenib resistance.
Externí odkaz:
https://doaj.org/article/d48c34daea6a4c3aa325c6346efbdca0
Publikováno v:
Molecules, Vol 23, Iss 1, p 27 (2017)
Methicillin-resistant Staphylococcus aureus (MRSA) is a serious threat to humans. Most existing antimicrobial drugs, including the β-lactam and quinoxiline classes, are not effective against MRSA. In this study, we synthesized 24 derivatives of malo
Externí odkaz:
https://doaj.org/article/c9e18e17b0d24c6c84847b95395f4133
Autor:
Jung-Chen Su, 蘇溶真
102
Obatoclax is a small molecule targeting BCL-2 family, and it is currently in clinical trial for leukemic patients. In this study, the new derivative, SC-2001, displays better anti-tumor effect than obatoclax on HCC in in vitro and in vivo ex
Obatoclax is a small molecule targeting BCL-2 family, and it is currently in clinical trial for leukemic patients. In this study, the new derivative, SC-2001, displays better anti-tumor effect than obatoclax on HCC in in vitro and in vivo ex
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/42062315478995425440
Autor:
Jung-Chen Su, 蘇溶真
98
Apoptosis plays an important role in the regulation of cellular activities in eukaryotes. One of the apoptotic pathways is the mitochondria-mediated intrinsic pathway which involves the release of the mitochondrial protein cytochrome c, resul
Apoptosis plays an important role in the regulation of cellular activities in eukaryotes. One of the apoptotic pathways is the mitochondria-mediated intrinsic pathway which involves the release of the mitochondrial protein cytochrome c, resul
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/29898058235527784961
Autor:
Ying-Hsuan Sun, Ying-Chung Jimmy Lin, Chia-En Huang, Jung-Chen Su, Chuan Ku, Chia-Ling Yang, Peng Shuai, Jhong-He Yu, Chia-Chun Tung, Shang-Che Kuo
As the most abundant tissue on Earth1, xylem is responsible for lateral growth in plants. Typical xylem has a radial system composed of ray parenchyma cells and an axial system of fusiform cells2. In most angiosperms, fusiform cells are a combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52cf9e5d9bc92c39fe92302892415282
https://doi.org/10.1101/2021.10.16.464627
https://doi.org/10.1101/2021.10.16.464627
Autor:
Jung Chen Su, Pei Rong Lin, Yeu Su, Ta Chung Chao, Yen Hsi Chen, Chung Wai Shiau, Shin Yi Chung
Publikováno v:
Cell Death Discovery, Vol 4, Iss 1, Pp 1-12 (2018)
Cell Death Discovery
Cell Death Discovery
Signal transducer and activator of transcription 3 (STAT3) has been shown to play a critical role in the maintenance of cancer stem cells (CSCs). Hence, the inhibition of STAT3 signaling has been suggested to be a viable therapeutic approach for canc