Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Junfen Shi"'
Publikováno v:
SLAS Discovery, Vol 27, Iss 2, Pp 107-113 (2022)
KRAS, the most frequently mutated oncogene in human cancers, was considered “undruggable” until the identification of small molecules that bind irreversibly to the mutant reactive cysteine at residue 12. Despite the encouraging anticancer activit
Externí odkaz:
https://doaj.org/article/55f6d9221cc340e28adac8eace267cf5
Autor:
Junfen Shi, Fang Li
Publikováno v:
European Journal of Gastroenterology & Hepatology.
Autor:
Junfen Shi, Fang Li
Publikováno v:
Ethiopian Journal of Health Development; Vol. 35 No. 4 (2021)
Background: Enhanced Recover After Surgery (ERAS) is a multidisciplinary multimodal approach used to treat surgical patients, which targets perioperative management optimization of results. This approach was first applied to patients who had undergon
Publikováno v:
SLAS discovery : advancing life sciences RD. 27(2)
KRAS, the most frequently mutated oncogene in human cancers, was considered "undruggable" until the identification of small molecules that bind irreversibly to the mutant reactive cysteine at residue 12. Despite the encouraging anticancer activity of
Publikováno v:
J Biol Chem
The endoplasmic reticulum–associated degradation (ERAD) pathway mediates the endoplasmic reticulum–to–cytosol retrotranslocation of defective proteins through protein complexes called retrotranslocons. Defective proteins usually have complex co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e17e7f46251f189a27569ce1871b45d
https://europepmc.org/articles/PMC6937559/
https://europepmc.org/articles/PMC6937559/
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29804 (2011)
The vertebrate skull evolved to protect the brain and sense organs, but with the appearance of jaws and associated forces there was a remarkable structural diversification. This suggests that the evolution of skull form may be linked to these forces,
Externí odkaz:
https://doaj.org/article/16621458a9254177b17d6c7947828435
Autor:
Junfen Shi, Philippe Young, Leonard King, Yanneck Suchier, M.T. Bah, Fabien Lefebvre, Martin Browne, D.G. Dunlop, Markus O. Heller
Publikováno v:
Medical Engineering & Physics. 37:995-1007
This paper is motivated by the need to accurately and efficiently measure key periosteal and endosteal parameters of the femur, known to critically influence hip biomechanics following arthroplasty. The proposed approach uses statistical shape and in
Publikováno v:
Journal of Healthcare Engineering
Journal of Healthcare Engineering, Vol 2017 (2017)
Journal of Healthcare Engineering, Vol 2017 (2017)
Overweight and obesity increase risks of knee osteoarthritis, which is a major cause of disability. Severe knee osteoarthritis can be treated by knee arthroplasty. Total knee arthroplasty has been used in overweight and obese patients; however, clini
Autor:
Junfen Shi1,2, Xianyan Hu1,2, Yuan Guo1,2, Linhan Wang1,2, Jia Ji1,2, Jiqiang Li1,2, Zai-Rong Zhang1,2 zrzhang@sioc.ac.cn
Publikováno v:
Journal of Biological Chemistry. 12/27/2019, Vol. 294 Issue 52, p20084-20096. 13p.
Publikováno v:
Computer Methods in Biomechanics and Biomedical Engineering. 17:1671-1684
Patient-specific finite element models of the implanted proximal femur can be built from pre-operative computed tomography scans and post-operative X-rays. However, estimating three-dimensional positioning from two-dimensional radiographs introduces