Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Junfa Li"'
Publikováno v:
Brain Circulation, Vol 9, Iss 4, Pp 228-239 (2023)
BACKGROUND: Ischemic stroke (IS) is a life-threatening condition with limited treatment options; thus, finding the potential key genes for novel therapeutic targets is urgently needed. This study aimed to explore novel candidate genes and pathways of
Externí odkaz:
https://doaj.org/article/87cc690dabd64a5e9363fd61b2f0edd3
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 25, Iss 4, Pp 683-698 (2020)
Stroke causes significant morbidity and mortality worldwide, for which no satisfactory preventive option currently exists. Hypoxic preconditioning (HPC) is a protective strategy for cerebral ischemic stroke. To this end, we have identified, Conventio
Externí odkaz:
https://doaj.org/article/4f293b24dc134fa6a952cb0b1e2dadaf
Publikováno v:
Cells, Vol 11, Iss 12, p 1940 (2022)
Synapses serve as the interface for the transmission of information between neurons in the central nervous system. The structural and functional characteristics of synapses are highly dynamic, exhibiting extensive plasticity that is shaped by neural
Externí odkaz:
https://doaj.org/article/83d28dca9e724121a4ffbd1c38afc1c8
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
We previously reported that the levels of astrocyte-derived interleukin-17A (IL-17A) increased both in the peri-infarct region and cerebrospinal fluid (CSF) of mice with 1-h middle cerebral artery (MCA) occlusion/12-h reperfusion (1-h MCAO/R 12 h)-in
Externí odkaz:
https://doaj.org/article/5421b2e84eb34dd880076652005c1b04
Autor:
Yao Liu, Ying Feng, Xiaojing Wang, Xue Yang, Ying Hu, Yuxin Li, Qun Zhang, Yunyi Huang, Ke Shi, Chongping Ran, Jie Hou, Li Jiang, Junfa Li, Xianbo Wang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Transarterial chemoembolization (TACE) represents a widely accepted treatment procedure for intermediate stage or unresectable hepatocellular carcinoma (HCC). However, few studies have evaluated serologic prognosis factors in patients wit
Externí odkaz:
https://doaj.org/article/ebced869403f4da2961054b49b2e6c54
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227481 (2020)
BACKGROUND:Ischemic Stroke (IS) is a major disease which greatly threatens human health. Recent studies showed sex-specific outcomes and mechanisms of cerebral ischemic stroke. This study aimed to identify the key changes of gene expression between m
Externí odkaz:
https://doaj.org/article/2e67477527a043df9cf85db7934cb5fa
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
We previously reported that astrocyte-derived proinflammatory cytokine interleukin (IL)-17A could aggravate neuronal ischemic injuries and strength autophagy both in oxygen-glucose deprivation (OGD)/reoxygenation (R)-treated neurons and peri-infarct
Externí odkaz:
https://doaj.org/article/9679e937cf42415eb2fc353ca3d8dc03
Publikováno v:
Journal of Diabetes Research, Vol 2018 (2018)
Diabetic encephalopathy is a complication of diabetes mellitus characterized by impaired cognitive functions. Protein kinase C (PKC) isoforms are rarely reported on diabetic encephalopathy, although they have been believed to play crucial roles in ot
Externí odkaz:
https://doaj.org/article/e13aadda9856451494ced39f1d680b38
Identification and Functional Analysis of MicroRNAs in Mice following Focal Cerebral Ischemia Injury
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 10, Pp 24302-24318 (2015)
Numerous studies have demonstrated that genes, RNAs, and proteins are involved in the occurrence and development of stroke. In addition, previous studies concluded that microRNAs (miRNAs or miRs) are closely related to the pathological process of isc
Externí odkaz:
https://doaj.org/article/b999e79f929a4d228096bc678a705630
Publikováno v:
Neurobiology of Disease, Vol 31, Iss 2, Pp 278-285 (2008)
Our previous research indicates that the extracellular signal-regulated kinase (ERK)-cyclic AMP-responsive-element-binding protein (CREB) signal system may be involved in the molecular mechanism of depression. The present study further investigated t
Externí odkaz:
https://doaj.org/article/de69a8324e274ae8b050e301275e04c9