Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Junetha, Syed"'
Autor:
Andreas Halner, Luke Hankey, Zhu Liang, Francesco Pozzetti, Daniel Szulc, Ella Mi, Geoffrey Liu, Benedikt M Kessler, Junetha Syed, Peter Jianrui Liu
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106610- (2023)
Summary: Cancer is a leading cause of mortality worldwide. Over 50% of cancers are diagnosed late, rendering many treatments ineffective. Existing liquid biopsy studies demonstrate a minimally invasive and inexpensive approach for disease detection b
Externí odkaz:
https://doaj.org/article/24c44c4a33ad41e3a0fc345f393e67db
Autor:
Junetha, Syed Jabarulla
0048
甲第19261号
理博第4116号
新制||理||1592(附属図書館)
32263
学位規則第4条第1項該当
Doctor of Science
Kyoto University
DGAM
甲第19261号
理博第4116号
新制||理||1592(附属図書館)
32263
学位規則第4条第1項該当
Doctor of Science
Kyoto University
DGAM
Externí odkaz:
http://hdl.handle.net/2433/202664
Autor:
Juri Na, Joseph A. Newman, Chee Kin Then, Junetha Syed, Iolanda Vendrell, Ignacio Torrecilla, Sophie Ellermann, Kristijan Ramadan, Roman Fischer, Anne E. Kiltie
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-17 (2021)
Abstract The human MRE11/RAD50/NBS1 (MRN) complex plays a crucial role in sensing and repairing DNA DSB. MRE11 possesses dual 3′−5′ exonuclease and endonuclease activity and forms the core of the multifunctional MRN complex. We previously ident
Externí odkaz:
https://doaj.org/article/3103fd513d43413eb4a4915b79d69200
Autor:
Anne E. Kiltie, Chee Kin Then, Sophie Ellermann, J.A. Newman, Junetha Syed, Ignacio Torrecilla, Iolanda Vendrell, Kristijan Ramadan, Juri Na, Roman Fischer
Publikováno v:
Cell Death & Disease
Cell death & disease, 12(2). Nature Publishing Group
Cell Death and Disease, Vol 12, Iss 2, Pp 1-17 (2021)
Cell death & disease, 12(2). Nature Publishing Group
Cell Death and Disease, Vol 12, Iss 2, Pp 1-17 (2021)
The human MRE11/RAD50/NBS1 (MRN) complex plays a crucial role in sensing and repairing DNA DSB. MRE11 possesses dual 3′−5′ exonuclease and endonuclease activity and forms the core of the multifunctional MRN complex. We previously identified a C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e55e65e62a3c0343b3c0eabc9e8bfa
https://doi.org/10.1038/s41419-021-03437-w
https://doi.org/10.1038/s41419-021-03437-w
Autor:
Iolanda Vendrell, Junetha Syed Jabarulla, Anne E. Kiltie, Judith Nicholson, Xin Ying Yeo, Benedikt M. Kessler, Roman Fischer
Publikováno v:
Frontiers in Oncology. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29628ae38dd380ef66420ce44843bc2e
https://doi.org/10.3389/conf.fonc.2019.01.00017
https://doi.org/10.3389/conf.fonc.2019.01.00017
Publikováno v:
Cell Chemical Biology. 23(11):1325-1333
Long noncoding RNAs (lncRNAs) play a pivotal role in the regulation of biological processes through various mechanisms that are not fully understood. Proposed mechanisms include regulation based on RNA-protein interactions, as well as RNA-RNA interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1e9f8fdc60dd9eec1a540fed72d8b7
http://hdl.handle.net/2433/230817
http://hdl.handle.net/2433/230817
Autor:
Junetha Syed, Anandhakumar Chandran, Yue Li, Hiroshi Sugiyama, Toshikazu Bando, Shinsuke Sato
Publikováno v:
ChemBioChem. 17:1905-1910
One of the major goals in DNA-based personalized medicine is the development of sequence-specific small molecules to target the genome. SAHA-PIPs belong to such class of small molecule. In the context of the complex eukaryotic genome, the differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5423ef4b1fd11b50e736090cde8ad0f
https://doi.org/10.1002/cbic.201600274
https://doi.org/10.1002/cbic.201600274
Autor:
Toshikazu Bando, Gengo Kashiwazaki, Hiroshi Sugiyama, Junetha Syed, Shinsuke Sato, Rhys Dylan Taylor, Kaori Hashiya, Anandhakumar Chandran
Publikováno v:
Nucleic Acids Research
Chemically engineered small molecules targeting specific genomic sequences play an important role in drug development research. Pyrrole-imidazole polyamides (PIPs) are a group of molecules that can bind to the DNA minor-groove and can be engineered t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3467ca790b850c1926e16d6a3a4b8fa2
http://hdl.handle.net/2433/216363
http://hdl.handle.net/2433/216363
Autor:
Junetha Syed, Ganesh N. Pandian, Gengo Kashiwazaki, Kaori Hashiya, Anandhakumar Chandran, Toshikazu Bando, Junichi Taniguchi, Shinsuke Sato, Hiroshi Sugiyama
Publikováno v:
Chembiochem : a European journal of chemical biology. 16(10)
Small molecules capable of modulating epigenetic signatures can activate the transcription of tissue-restricted genes in a totally unrelated cell type and have potential use in epigenetic therapy. To provide an example for an initial approach, we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4158fb31b2ead9848ac1604005b639b8
https://pubmed.ncbi.nlm.nih.gov/25900774
https://pubmed.ncbi.nlm.nih.gov/25900774
Publikováno v:
Long Noncoding RNAs ISBN: 9784431555759
RNA plays a central role in cell development and differentiation by regulating the flow of essential genetic information into the dynamic molecular machinery within the cell. Recently, large-scale sequencing techniques to analyze mammalian transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3416b263b5b6ae7dc1cb85bcfb0f4d88
https://doi.org/10.1007/978-4-431-55576-6_2
https://doi.org/10.1007/978-4-431-55576-6_2