Zobrazeno 1 - 10
of 153
pro vyhledávání: '"June R. Scott"'
Publikováno v:
The Journal of Immunology. 195:5025-5034
The induction of a potent humoral and cellular immune response in mucosal tissue is important for the development of an effective HIV vaccine. Most of the current HIV vaccines under development use the i.m. route for immunization, which is relatively
Autor:
Sarah T. Pruett, Julia V. Bugrysheva, Dennis C. Liotta, June R. Scott, Haipeng Hu, Shuli Mao, James P. Snyder
Publikováno v:
European Journal of Medicinal Chemistry. 82:120-126
Group A streptococcus (GAS) is a Gram-positive bacterium, which can cause multiple types of disease from mild infections of skin and throat to invasive and life-threatening infections. Recently RNase J1 and J2 were found to be essential for the growt
Publikováno v:
Infection and Immunity. 79:4201-4209
Genes encoding one or more Ser/Thr protein kinases have been identified recently in many bacteria, including one ( stk ) in the human pathogen Streptococcus pyogenes (group A streptococcus [GAS]). We report that in GAS, stk is required to produce dis
Autor:
Jessica C. Seeliger, Arash Komeili, Colleen M. K. Reynoso, Shawn K. Desai, Aaron W. Puri, Carolyn R. Bertozzi, Dorothée Murat, Justin P. Gallivan, Shana Topp, June R. Scott, Aimee Shen, Ian S. Goldlust
Publikováno v:
Applied and Environmental Microbiology. 76:7881-7884
We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We ant
Autor:
June R. Scott, Julia V. Bugrysheva
Publikováno v:
Molecular Microbiology. 75:731-743
The paralogous ribonucleases J1 and J2, recently identified in Bacillus subtilis, have both endoribonucleolytic and 5'-to-3' exoribonucleolytic activities and participate in degradation and regulatory processing of mRNA. RNases J1 and J2 have partial
Publikováno v:
Journal of Bacteriology. 191:673-677
We found that the global regulatory two-component signal transduction system CovRS mediates the ability of group A streptococcus (GAS) to grow under two stresses encountered during infection: iron starvation and the presence of LL-37. We also showed
Autor:
June R. Scott, Dorothea Zähner
Publikováno v:
Journal of Bacteriology. 190:527-535
Pili are a major surface feature of the human pathogen Streptococcus pyogenes (group A streptococcus [GAS]). The T3 pilus is composed of a covalently linked polymer of protein T3 (formerly Orf100 or Fct3) with an ancillary protein, Cpa, attached. A p
Publikováno v:
Journal of Bacteriology. 189:1866-1873
The impressive disease spectrum of Streptococcus pyogenes (the group A streptococcus [GAS]) is believed to be determined by its ability to modify gene expression in response to environmental stimuli. Virulence gene expression is controlled tightly by
Autor:
June R. Scott, Timothy C. Barnett
Publikováno v:
Annual Review of Microbiology. 60:397-423
Surface proteins are critical in determining the identifying characteristics of individual bacteria and their interaction with the environment. Because the structure of the cell surface is the major characteristic that distinguishes gram-positive fro
Autor:
Dorothea Zähner, June R. Scott
Publikováno v:
Molecular Microbiology. 62:320-330
Bacteria attach to their appropriate environmental niche by using adhesins. To maximize their contact with the environment, adhesins are often present on the ends of long hairlike structures called pili. Recently, attention has focused on pili of Gra