Zobrazeno 1 - 10
of 103
pro vyhledávání: '"June K. Dunnick"'
Autor:
Keith R. Shockley, June K. Dunnick
Publikováno v:
Frontiers in Toxicology, Vol 4 (2023)
Exposure to environmental hazards occurs at different stages of our lifetime–infant, child, adult. This study integrates recently published toxicogenomics data to examine how exposure to a known rat chemical carcinogen (pentabrominated diphenyl eth
Externí odkaz:
https://doaj.org/article/52a8d337302e48209a3cd792eb6fefb2
Autor:
June K. Dunnick, Arun R. Pandiri, B.A. Merrick, Grace E. Kissling, Helen Cunny, Esra Mutlu, Suramya Waidyanatha, Robert C. Sills, Hue-Hua. L. Hong, Thai-Vu Ton, Timonthy Maynor, Leslie Rescio, Siuzanne L. Phillips, Michael J. Devito, Amy Brix
Publikováno v:
Data in Brief, Vol 21, Iss , Pp 2125-2128 (2018)
This article describes data related to the research article entitled “Carcinogenic activity of pentabrominated diphenyl ether mixture (DE-71) in rats and mice” (Dunnick et al., 2018). PBDE-induced hepatocellular tumors harbored Hras and Ctnnb1 mu
Externí odkaz:
https://doaj.org/article/49a0e9e4a1bb4fab94be71dec77a6871
Autor:
Keith R. Shockley, Michelle C. Cora, David E. Malarkey, Daven Jackson-Humbles, Molly Vallant, Brad J. Collins, Esra Mutlu, Veronica G. Robinson, Surayma Waidyanatha, Amy Zmarowski, Nicholas Machesky, Jamie Richey, Sam Harbo, Emily Cheng, Kristin Patton, Barney Sparrow, June K. Dunnick
Publikováno v:
Data in Brief, Vol 32, Iss , Pp 106136- (2020)
Large-scale gene expression analysis of legacy* and emerging** brominated flame retardants were conducted in the male Harlan Sprague Dawley rat [1]. Each animal was dosed for 5 days with the chemical at concentrations of 0.1 – 1000 μmol/kg body we
Externí odkaz:
https://doaj.org/article/ef6e90cf26774df69f25a85f539a8103
Autor:
Surayma Waidyanatha, June K. Dunnick, Daven N. Jackson-Humbles, Esra Mutlu, Sam J. Harbo, David E. Malarkey, Barney Sparrow, Keith R. Shockley, Emily Cheng, Molly Vallant, Nicholas J. Machesky, B Collins, Michelle C. Cora, Veronica G. Robinson, Kristin Patton, Amy Zmarowski, Jamie S. Richey
Publikováno v:
Toxicol Lett
The relative toxicity of three legacy and six emerging brominated flame retardants* was studied in the male Harlan Sprague Dawley rat. The hepatocellular and thyroid toxicity of each flame retardant was evaluated following five-day exposure to each o
Autor:
Sukhdev S. Brar, June K. Dunnick, Kevin Gerrish, Ralph E. Wilson, Esra Mutlu, Daniel L. Morgan, Arun R. Pandiri, Keith R. Shockley, Thai-Vu T. Ton, Amy E. Brix, Gregory S. Travlos, Suramya Waidyanatha
Publikováno v:
Toxicol Pathol
Human exposure to pentabromodiphenyl ether (PBDE) mixture (DE-71) and its PBDE-47 congener can occur both in utero and during lactation. Here we tested the hypothesis that PBDE-induced neonatal hepatic transcriptomic alterations in Wistar Han rat pup
Autor:
Timonthy Maynor, June K. Dunnick, Leslie Rescio, Suramya Waidyanatha, Thai-Vu T. Ton, Grace E. Kissling, Helen Cunny, Siuzanne L. Phillips, Hue-Hua L. Hong, Esra Mutlu, Michael J. DeVito, Amy E. Brix, Robert C. Sills, Bruce Alex Merrick, Arun R. Pandiri
Publikováno v:
Data in Brief
Data in Brief, Vol 21, Iss, Pp 2125-2128 (2018)
Data in Brief, Vol 21, Iss, Pp 2125-2128 (2018)
This article describes data related to the research article entitled “Carcinogenic activity of pentabrominated diphenyl ether mixture (DE-71) in rats and mice” (Dunnick et al., 2018). PBDE-induced hepatocellular tumors harbored Hras and Ctnnb1 mu
Publikováno v:
Journal of Toxicologic Pathology
Herbal products have been in use for many years, but they are becoming more and more popular in recent years, and they are currently in widespread use throughout the world. In this review article we describe the histopathologic findings found after e
Autor:
Sukhdev S. Brar, Amy E. Brix, T. V. Ton, Daniel L. Morgan, Esra Mutlu, June K. Dunnick, Suramya Waidyanatha, Ralph E. Wilson, Grace E. Kissling, Arun R. Pandiri, Keith R. Shockley, Kevin Gerrish
Publikováno v:
Archives of Toxicology. 92:3415-3433
Pentabromodiphenyl ethers (PBDE) are found in human tissue, in household dust, and in the environment, and a particular concern is the potential for the induction of cancer pathways from these fat-soluble persistent organic pollutants. Only one PBDE
Autor:
Bruce Alex Merrick, Grace E. Kissling, Esra Mutlu, Amy E. Brix, Arun R. Pandiri, T. V. Ton, Helen Cunny, Suramya Waidyanatha, Hue-Hua L. Hong, Michael J. DeVito, Leslie Recio, Suzanne L. Phillips, Timothy Maynor, Robert C. Sills, June K. Dunnick
Publikováno v:
Toxicology Reports, Vol 5, Iss, Pp 615-624 (2018)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Pentabrominated diphenyl ether (PBDE) mixture was a multispecies carcinogen causing liver tumors in male and female rats and mice. • Hras or Ctnnb1 mutations characterized the PBDE-induced liver tumors. • PB
Highlights • Pentabrominated diphenyl ether (PBDE) mixture was a multispecies carcinogen causing liver tumors in male and female rats and mice. • Hras or Ctnnb1 mutations characterized the PBDE-induced liver tumors. • PB
Autor:
Takashi Shimbo, Amy Brix, Deepak Mav, Paul A. Wade, June K. Dunnick, John Roberts, Ruchir R. Shah
Publikováno v:
International Journal of Toxicology. 36:229-238
DE-71, a commercial mixture of polybrominated diphenyl ethers widely used in flame retardants, is a pervasive environmental contaminant due to its continuing release from waste material and its long half-life in humans. Although the genotoxic potenti