Zobrazeno 1 - 10
of 76
pro vyhledávání: '"June Goto"'
Autor:
Farrah N. Brown, Eri Iwasawa, Crystal Shula, Elizabeth M. Fugate, Diana M. Lindquist, Francesco T. Mangano, June Goto
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Neonatal hydrocephalus is a congenital abnormality resulting in an inflammatory response and microglial cell activation both clinically and in animal models. Previously, we reported a mutation in a motile cilia gene, Ccdc39 that d
Externí odkaz:
https://doaj.org/article/47e6231a38094abf9e1435ce3797e875
Autor:
Alicia Bedolla, Aleksandr Taranov, Fucheng Luo, Jiapeng Wang, Flavia Turcato, Elizabeth M. Fugate, Nigel H. Greig, Diana M. Lindquist, Steven A. Crone, June Goto, Yu Luo
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Two recently developed novel rodent models have been reported to ablate microglia, either by genetically targeting microglia (via Cx3cr1-creER: iDTR + Dtx) or through pharmacologically targeting the CSF1R receptor with its inhibit
Externí odkaz:
https://doaj.org/article/9e9169c511894de18604fa32ac1bba9c
Autor:
A. Scott Emmert, Eri Iwasawa, Crystal Shula, Preston Schultz, Diana Lindquist, R. Scott Dunn, Elizabeth M. Fugate, Yueh-Chiang Hu, Francesco T. Mangano, June Goto
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 11 (2019)
Neonatal hydrocephalus affects about one child per 1000 births and is a major congenital brain abnormality. We previously discovered a gene mutation within the coiled-coil domain-containing 39 (Ccdc39) gene, which causes the progressive hydrocephalus
Externí odkaz:
https://doaj.org/article/820c6ed3f79b41dfa9bea4f4ba5e2192
Autor:
Eri Iwasawa, Farrah N. Brown, Crystal Shula, Fatima Kahn, Sang Hoon Lee, Temugin Berta, David R. Ladle, Kenneth Campbell, Francesco T. Mangano, June Goto
Publikováno v:
J Neurosci
Neonatal hydrocephalus presents with various degrees of neuroinflammation and long-term neurologic deficits in surgically treated patients, provoking a need for additional medical treatment. We previously reported elevated neuroinflammation and sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea9f253b56df125398779131add9c80
https://doi.org/10.1523/jneurosci.1160-21.2021
https://doi.org/10.1523/jneurosci.1160-21.2021
Autor:
Shilpa Prabhakar, Xuan Zhang, June Goto, Sangyeul Han, Charles Lai, Roderick Bronson, Miguel Sena-Esteves, Vijaya Ramesh, Anat Stemmer-Rachamimov, David J. Kwiatkowski, Xandra O. Breakefield
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 22-31 (2015)
We examined the potential benefit of gene therapy in a mouse model of tuberous sclerosis complex (TSC) in which there is embryonic loss of Tsc1 (hamartin) in brain neurons. An adeno-associated virus (AAV) vector (serotype rh8) expressing a tagged for
Externí odkaz:
https://doaj.org/article/8eae6760b48943a698ff72cfc816c4b9
Autor:
Phan Q. Duy, Stefan C. Weise, Claudia Marini, Xiao-Jun Li, Dan Liang, Peter J. Dahl, Shaojie Ma, Ana Spajic, Weilai Dong, Jane Juusola, Emre Kiziltug, Adam J. Kundishora, Sunil Koundal, Maysam Z. Pedram, Lucia A. Torres-Fernández, Kristian Händler, Elena De Domenico, Matthias Becker, Thomas Ulas, Stefan A. Juranek, Elisa Cuevas, Le Thi Hao, Bettina Jux, André M. M. Sousa, Fuchen Liu, Suel-Kee Kim, Mingfeng Li, Yiying Yang, Yutaka Takeo, Alvaro Duque, Carol Nelson-Williams, Yonghyun Ha, Kartiga Selvaganesan, Stephanie M. Robert, Amrita K. Singh, Garrett Allington, Charuta G. Furey, Andrew T. Timberlake, Benjamin C. Reeves, Hannah Smith, Ashley Dunbar, Tyrone DeSpenza, June Goto, Arnaud Marlier, Andres Moreno-De-Luca, Xin Yu, William E. Butler, Bob S. Carter, Evelyn M. R. Lake, R. Todd Constable, Pasko Rakic, Haifan Lin, Engin Deniz, Helene Benveniste, Nikhil S. Malvankar, Juvianee I. Estrada-Veras, Christopher A. Walsh, Seth L. Alper, Joachim L. Schultze, Katrin Paeschke, Angelika Doetzlhofer, F. Gregory Wulczyn, Sheng Chih Jin, Richard P. Lifton, Nenad Sestan, Waldemar Kolanus, Kristopher T. Kahle
Publikováno v:
Nat Neurosci
Nature neuroscience 25(4), 458-473 (2022). doi:10.1038/s41593-022-01043-3
Nature neuroscience 25(4), 458-473 (2022). doi:10.1038/s41593-022-01043-3
Hydrocephalus, characterized by cerebral ventricular dilatation, is routinely attributed to primary defects in cerebrospinal fluid (CSF) homeostasis. This fosters CSF shunting as the leading reason for brain surgery in children despite considerable d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7188034c8e54b35384ea495840fb8d5
https://pubmed.ncbi.nlm.nih.gov/35379995
https://pubmed.ncbi.nlm.nih.gov/35379995
Autor:
Bernadette C. Holdener, Steven J. Berardinelli, June Goto, Robert S. Haltiwanger, Sanjiv Neupane, Atsuko Ito
Publikováno v:
Glycobiology
Peters plus syndrome, characterized by defects in eye and skeletal development with isolated cases of ventriculomegaly/hydrocephalus, is caused by mutations in the β3-glucosyltransferase (B3GLCT) gene. In the endoplasmic reticulum, B3GLCT adds gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b9b1ce8c427cf584f413583cb6a366
https://europepmc.org/articles/PMC8579228/
https://europepmc.org/articles/PMC8579228/
Autor:
Edith Mbabazi Kabachelor, William E. Butler, James M. Johnston, Kristopher T. Kahle, Carol Nelson-Williams, James R. Broach, Kaya Bilguvar, August A Allocco, Laura R. Ment, Andrew T. Timberlake, Peña, Peter Ssenyonga, Shozeb Haider, Christopher Castaldi, Arnaud Marlier, Bulent Guclu, Xue Zen, Steven J. Schiff, Rebecca L. Walker, Benjamin C. Reeves, James R. Knight, William J. Sullivan, Michael L. DiLuna, Weilai Dong, Bermans J. Iskandar, Yasar Bayri, Gregory G. Heuer, Boyang Li, Michael L.J. Apuzzo, Yener Sahin, Charuta G. Furey, Shreyas Panchagnula, Daniel H. Geschwind, Hannah Smith, Richard P. Lifton, Duy Phan, Michael C. Sierant, Sheng Chih Jin, Eric M. Jackson, Edward R. Smith, Tyrone DeSpenza, Irina Tikhonova, Murat Gunel, Andres Moreno-De-Luca, Nenad Sestan, Boris Keren, June Goto, Seth L. Alper, Charles C. Duncan, Adam J. Kundishora, Shrikant Mane, Ellen J. Hoffman, Francesco T. Mangano, Helena, Ashley Dunbar, Jason K. Karimy, Benjamin C. Warf, David D. Limbrick, Qiongshi Lu, Christine Hehnly, Sierra B Conine, Li Ge
Publikováno v:
Neurosurgery. 67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c037174cfc0082a75a8d10c5f0695eb
https://doi.org/10.1093/neuros/nyaa447_572
https://doi.org/10.1093/neuros/nyaa447_572
Autor:
F. Gregory Wulczyn, Claudia Marini, Carol Nelson-Williams, Daniel J. Foster, William J. Sullivan, Suel Kee Kim, Todd Constable, Elisa Cuevas, Richard P. Lifton, Waldemar Kolanus, June Goto, August A Allocco, Mingfeng Li, Charuta G. Furey, Yonghyun Ha, Le Hao, Xue Zeng, Sheng Chih Jin, Arnaud Marlier, Haifan Lin, Bettina Jux, Duy Phan, Amar H. Sheth, Yiying Yang, Evelyn Lake, Lucia A. Torres-Fernández, Weilai Dong, Frank J. Slack, Benjamin C. Reeves, Yutaka Takeo, André M. M. Sousa, Andres Moreno-De-Luca, Nenad Sestan, Stefan Weise, Tyrone DeSpenza, Fuchen Liu, Adam J. Kundishora, Ashley Dunbar, Benjamin C. Warf, Kristopher T. Kahle, Hannah Smith, Kartiga Selvaganesan, Seth L. Alper
Publikováno v:
Neurosurgery. 67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::698a1e852f262703c8ddc00e5c0b447c
https://doi.org/10.1093/neuros/nyaa447_576
https://doi.org/10.1093/neuros/nyaa447_576
Autor:
Shilpa Prabhakar, June Goto, Xuan Zhang, Miguel Sena-Esteves, Roderick Bronson, Jillian Brockmann, Davide Gianni, Gregory R. Wojtkiewicz, John W. Chen, Anat Stemmer-Rachamimov, David J. Kwiatkowski, Xandra O. Breakefield
Publikováno v:
PLoS ONE, Vol 8, Iss 11 (2013)
Externí odkaz:
https://doaj.org/article/59a8cfa1c2a84e77bf5613cc4bed8e85