Bacillus Calmette–Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice

Autor: L. Charlotte J. de Bree, Renoud J. Marijnissen, Junda M. Kel, Sietske K. Rosendahl Huber, Peter Aaby, Christine Stabell Benn, Marcel V. W. Wijnands, Dimitri A. Diavatopoulos, Reinout van Crevel, Leo A. B. Joosten, Mihai G. Netea, John Dulos

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Avian influenza A of the subtype H7N9 has been responsible for almost 1,600 confirmed human infections and more than 600 deaths since its first outbreak in 2013. Although sustained human-to-human transmission has not been reported yet, further adapta

Externí odkaz: https://doaj.org/article/7a86a7e49a1b4fd5a94f8b6ec52de8d7

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Mannosylated PLP 139–151 induces peptide-specific tolerance to experimental autoimmune encephalomyelitis

Autor: Luca, Mariken E., Kel, Junda M., van Rijs, Wouter, Wouter Drijfhout, Jan, Koning, Frits, Nagelkerken, Lex ^*

Publikováno v: In Journal of Neuroimmunology 2005 160(1):178-187

TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity

Autor: Tommy Regen, Dominika Lukas, Ingo Kleiter, Junda M. Kel, Florian Wanke, Marco Prinz, Ari Waisman, Ilgiz A. Mufazalov, Boris Reizis, Nir Yogev, Yilang Tang, Björn E. Clausen, Werner Müller, Florian C. Kurschus

Publikováno v: Lukas, D, Yogev, N, Kel, J M, Regen, T, Mufazalov, I A, Tang, Y, Wanke, F, Reizis, B, Müller, W, Kurschus, F C, Prinz, M, Kleiter, I, Clausen, B E & Waisman, A 2017, ' TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity ', Proceedings of the National Academy of Sciences of the United States of America . https://doi.org/10.1073/pnas.1615065114
Proceedings of the National Academy of Sciences of the U.S.A., 114(8), E1480-E1489. National Academy of Sciences

TGF-β is an anti-inflammatory cytokine whose signaling is negatively controlled by Smad7. Previously, we established a role for Smad7 in the generation of autoreactive T cells; however, the function of Smad7 in dendritic cells (DCs) remains elusive.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c929109501eef92a1d2d017435b84f8
https://pure.manchester.ac.uk/ws/files/52608935/PNAS_2017_Lukas_E1480_9.pdf

Conditional Deletion of TGF-βR1 Using Langerin-Cre Mice Results in Langerhans Cell Deficiency and Reduced Contact Hypersensitivity

Autor: Sonja Zahner, Björn E. Clausen, Inge Brouwers-Haspels, Cerithsa A. E. Martina, Marian A. van Roon, Junda M. Kel

Publikováno v: Journal of immunology (Baltimore, Md., 187(10), 5069-5076. American Association of Immunologists
Journal of Immunology, 187(10), 5069-5076. American Association of Immunologists

The critical role of Langerhans cells (LC) in contact hypersensitivity (CHS) was recently questioned in studies using different LC-depletion mouse models. On one hand, inducible ablation of LC led to diminished ear swelling, suggesting functional red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df63e80096c50853cf366e2ee78ac5a0
https://doi.org/10.4049/jimmunol.1101880