Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Junchi Hu"'
Autor:
Jiaqi Wang, Jiying Zhu, Junchi Hu, Ziruoyu Wang, Xiaobo Wang, Jianbo Pan, Yiwei Chu, Zengxia Li, Wei Jiang, Chunmin Liang, Jun Hou, Jianming Guo, Yongjun Dang, Shuai Jiang
Publikováno v:
Genes and Diseases, Vol 10, Iss 6, Pp 2586-2596 (2023)
Bladder cancer (BLCA) remains a difficult malignancy to manage because of its high recurrence, intense follow-up, and invasive diagnostic and treatment techniques. Immune checkpoint inhibitors (ICIs) have forged a new direction for the treatment of B
Externí odkaz:
https://doaj.org/article/ab55dbb08e7340e6b66b4b06e283d6da
Autor:
Ruina Wang, Lei Xiao, Jianbo Pan, Guangsen Bao, Yunmei Zhu, Di Zhu, Jun Wang, Chengfeng Pei, Qinfeng Ma, Xian Fu, Ziruoyu Wang, Mengdi Zhu, Guoxiang Wang, Ling Gong, Qiuping Tong, Min Jiang, Junchi Hu, Miao He, Yun Wang, Tiejun Li, Chunmin Liang, Wei Li, Chunmei Xia, Zengxia Li, Dengke K. Ma, Minjia Tan, Jun Yan Liu, Wei Jiang, Cheng Luo, Biao Yu, Yongjun Dang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Induction of hypothermia during hibernation/torpor enables certain mammals to survive under extreme environmental conditions. However, pharmacological induction of hypothermia in most mammals remains a huge challenge. Here we show that a nat
Externí odkaz:
https://doaj.org/article/994188ebcab5466fab11651b85358e5d
Autor:
Yuanyuan Zhang, Jing Huang, Bing Li, Jin Yu, Xiaobo Wang, Shiyu Shen, Ruina Wang, Hongru Tao, Junchi Hu, Hualiang Jiang, Kaixian Chen, Cheng Luo, Yongjun Dang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/417fb981fcae4ac29843cc2102fbc22e
Autor:
Fang Ren, Junchi Hu, Yongjun Dang, Haijun Deng, Jihua Ren, Shengtao Cheng, Ming Tan, Hui Zhang, Xin He, Haibo Yu, Juan Zhang, Zhenzhen Zhang, Weixian Chen, Jieli Hu, Xuefei Cai, Yuan Hu, Ailong Huang, Juan Chen
Publikováno v:
Journal of Medical Virology. 95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfd5295b7a155400f3a4e4e6ad9d252b
https://doi.org/10.1002/jmv.28578
https://doi.org/10.1002/jmv.28578
Autor:
Zhifeng Chen, Bing Zhou, Cheng Luo, Junchi Hu, Chinatsu Otomo, Xie Yuli, Yongjun Dang, Liyan Yue, Yuanyuan Zhang, Lianchun Li, Naixia Zhang, Wei Wan, Junyan Lu, Hualiang Jiang, Takanori Otomo, Yi Wen, Quanfu Li, Lin Tingting, Hongru Tao, Zhiyi Yao, Hong Ding, Pan Xu, Mingrui Zhu, Bidong Zhang, Minjia Tan, Kaixian Chen, Shijie Fan
Publikováno v:
Angew Chem Int Ed Engl
The autophagic ubiquitin-like protein LC3 functions through interactions with LC3-interaction regions (LIRs) of other autophagy proteins, including autophagy receptors, which stands out as a promising protein-protein interaction (PPI) target for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208993b70ca522f483ad2e1adae36341
https://doi.org/10.1002/anie.202109464
https://doi.org/10.1002/anie.202109464
Autor:
Jin-Pin Liu, Si-Yu Cen, Zian Xue, Tian-Xiang Wang, Yun Gao, Jia Zheng, Cheng Zhang, Junchi Hu, Shenyou Nie, Yue Xiong, Kun-Liang Guan, Hai-Xin Yuan
Publikováno v:
ACS chemical biology. 17(12)
Ferroptosis is a nonapoptotic form of cell death characterized by iron-dependent lipid peroxidation and has been implicated in multiple pathological conditions. Glutathione peroxidase 4 (GPX4) plays an essential role in inhibiting ferroptosis by elim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6d682e458721464085040c5dd9297c
https://pubmed.ncbi.nlm.nih.gov/36446024
https://pubmed.ncbi.nlm.nih.gov/36446024
Autor:
Yongjun Dang, Rui-Na Wang, Lei Xiao, Jianpo Pan, Di Zhu, Jun Wang, Chengfeng Pei, Qinfeng Ma, Guangsen Bao, Ziruoyu Wang, Mengdi Zhu, Guoxiang Wang, Ling Gong, Qiuping Tong, Min Jiang, Junchi Hu, Miao He, Yun Wang, Tiejun li, Wei Li, Chun-Min Liang, Zengxia Li, Dengke Ma, Minjia Tan, Jun-Yan Liu, Wei Jiang, Cheng Luo, Biao Yu
Hibernation/torpor enables certain mammals to survive under extreme environmental conditions. However, pharmacological induction of hibernation-like or torpor state in most mammals remains a huge challenge. Here we show that a natural product P57 pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ae71744707fc27d0214a68efd64c163
https://doi.org/10.21203/rs.3.rs-1518013/v1
https://doi.org/10.21203/rs.3.rs-1518013/v1
Autor:
Lin Li, Lijuan Fu, Xuemei Chen, Junchi Hu, Gwendolyn Gonzalez, Yinsheng Wang, Yanhui Xu, Changjun You, Jie Li, Weili Miao, Weifeng Gu, Lichao Li, Xiaoxia Dai, Ruidong Li, Yonghui Zhao
Publikováno v:
Anal Chem
5-Methylcytosine is found in both DNA and RNA; although its functions in DNA are well established, the exact role of 5-methylcytidine (m(5)C) in RNA remains poorly defined. Here we identified, by employing a quantitative proteomics method, multiple c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37765f1b715c985aaac1145ae9975acc
https://doi.org/10.1021/acs.analchem.9b04505
https://doi.org/10.1021/acs.analchem.9b04505
Publikováno v:
Computational Biology and Chemistry. 100:107751
Many works in computational drug discovery require the conformer generation of small molecules. Most existing tools aim to generate diverse conformers and deal with all of the rotatable bonds without distinction. There are some problems in existing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b38ebaa3ebf33c8e403651f214a748
https://doi.org/10.1016/j.compbiolchem.2022.107751
https://doi.org/10.1016/j.compbiolchem.2022.107751
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1862:1667-1679
Background DNMT3A, as de novo DNA methyltransferase, is essential for regulating gene expression through cellular development and differentiation. The functions of DNMT3A rely on its oligomeric states and allosteric regulations between its catalytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed3e541bcd9cb8a40b3b4c11f7f9e03
https://doi.org/10.1016/j.bbagen.2018.04.015
https://doi.org/10.1016/j.bbagen.2018.04.015