Zobrazeno 1 - 10
of 92
pro vyhledávání: '"JunYing Miao"'
Activation of GRP78 ATPase suppresses A549 lung cancer cell migration by promoting ITGB4 degradation
Publikováno v:
Cell Adhesion & Migration, Vol 16, Iss 1, Pp 107-114 (2022)
Hypochlorous acid (HOCl) is an essential signal molecule in cancer cells. Activated GRP78 ATPase by a HOCl probe named ZBM-H inhibits lung cancer cell growth. However, the role and underlying mechanism of GRP78 ATPase in lung cancer cell migration ha
Externí odkaz:
https://doaj.org/article/90f7933d011741edb4173909a20f181a
Autor:
XiaoLing Cui, XiaoTan Wang, Jie Wen, Xiao Li, Nan Li, XuXiao Hao, BaoXiang Zhao, Xunwei Wu, JunYing Miao
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Human dermal fibroblasts (HDFs) have the potential to differentiate into vascular endothelial cells (VECs), but their differentiation rate is low and the mechanism involved is not clear. The small molecule pathway controls the phe
Externí odkaz:
https://doaj.org/article/250217962fd34a14969aaf3ca57ccd5a
Autor:
Yuejun Yang, Xinpeng Chen, Wen Yao, Xiaoling Cui, Na Li, ZhaoMin Lin, Baoxiang Zhao, Junying Miao
Publikováno v:
Cellular & Molecular Biology Letters, Vol 26, Iss 1, Pp 1-16 (2021)
Abstract Background Esterase D (ESD) is a nonspecific esterase that detoxifies formaldehyde. Many reports have stated that ESD activity is associated with a variety of physiological and pathological processes. However, the detailed signaling pathway
Externí odkaz:
https://doaj.org/article/e6efa56f7c8d4e269979ec278393f83d
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Sulfur dioxide (SO2) is an important gas signal molecule produced in the cardiovascular system, so it has an important regulatory effect on human umbilical vascular endothelial cells (HUVECs). Studies have shown that high glucose (HG) has become the
Externí odkaz:
https://doaj.org/article/4d945ef5bf664c17b48ecb81dbf06bd8
Autor:
Jie Wen, Wenqian Chen, Baoxiang Zhao, Qiuping Xu, Chang Liu, Qun Zhang, Zhiwei Xie, Yonggan Yan, Jing Guo, Jun Huang, Junying Miao, Xunwei Wu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-17 (2021)
Abstract p53, the major tumor suppressor, is frequently mutated in many cancers, and up to 84% of human melanomas harbor wild-type p53, which is considered to be an ideal target for melanoma therapy. Here, we evaluated the antitumor activity of a car
Externí odkaz:
https://doaj.org/article/d6c1f34074804908b7f639bf43e64a22
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Oxidized low-density lipoprotein (oxLDL) induces vascular endothelial cell (VEC) injury and atherosclerosis through activating endoplasmic reticulum stress. Expression of glucose-regulated protein 94 (Grp94) is induced by endoplasmic reti
Externí odkaz:
https://doaj.org/article/c0aecba4267c4146bf19409034dea588
Autor:
Xiaoling Cui, Jie Wen, Nan Li, Xuxiao Hao, Shangli Zhang, Baoxiang Zhao, Xunwei Wu, Junying Miao
Publikováno v:
Cells, Vol 11, Iss 19, p 3126 (2022)
Human dermal fibroblasts (HDFs) have the potential to differentiate into endothelial cells (VECs). In our previous research, we reported that a hypochlorous acid (HOCl) probe CPP efficiently induced the differentiation of HDFs into VECs, however, the
Externí odkaz:
https://doaj.org/article/25e8ebb384124184869c334633f89ce5
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-11 (2018)
Abstract Background Bone marrow-derived mesenchymal stem cells (BMSCs) are gradually getting attention because of its multi-directional differentiation potential, hematopoietic support, and promotion of stem cell implantation. However, cultured BMSCs
Externí odkaz:
https://doaj.org/article/544df4eb8a7f4532b5c8bf174763f3d5
Autor:
Xuan Zhao, WenLiang Dong, YuanDi Gao, Dong-Shoo Shin, Qing Ye, Le Su, Fan Jiang, BaoXiang Zhao, JunYing Miao
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Increasing evidence indicates that Nrf-2, named the nuclear factor-erythroid 2-related factor, may perform anticancer function. In this study, a series of novel substituted phenyl- (3-methyl-1H-indol-2-yl)-prop-2-en-1-one (indolyl-chalcone)
Externí odkaz:
https://doaj.org/article/096f1f9f54a845be8fc892dc518dcd89
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Bone marrow stromal cells (BMSCs) can differentiate into vascular endothelial cells (VECs). It is regarded as an important solution to cure many diseases, such as ischemic diseases and diabetes. However, the mechanisms underlying BMSC differentiation
Externí odkaz:
https://doaj.org/article/38fa2f475495471197f64e3b3d6d9b14