Myeloid cells interact with a subset of thyrocytes to promote their migration and follicle formation through NF-κB

Autor: Rui-Meng Yang, Shi-Yang Song, Feng-Yao Wu, Rui-Feng Yang, Yan-Ting Shen, Ping-Hui Tu, Zheng Wang, Jun-Xiu Zhang, Feng Cheng, Guan-Qi Gao, Jun Liang, Miao-Miao Guo, Liu Yang, Yi Zhou, Shuang-Xia Zhao, Ming Zhan, Huai-Dong Song

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Abstract The pathogenesis of thyroid dysgenesis (TD) is not well understood. Here, using a combination of single-cell RNA and spatial transcriptome sequencing, we identify a subgroup of NF-κB-activated thyrocytes located at the center of thyroid tis

Externí odkaz: https://doaj.org/article/de96cbfe3add49e090d84426e4f595ec

The mutation screening in candidate genes related to thyroid dysgenesis by targeted next‐generation sequencing panel in the Chinese congenital hypothyroidism

Autor: Feng Cheng, Jun-Xiu Zhang, Ya Fang, Rui-Jia Zhang, Guang-Lin Yang, Jun Liang, Feng Sun, Cao-Xu Zhang, Zheng Wang, Huai-Dong Song, Shuang-Xia Zhao, Feng-Yao Wu

Publikováno v: Clinical Endocrinology. 96:617-626

Objective Congenital hypothyroidism (CH) is known to be due to thyroid dyshormonogenesis (DH), which is mostly inherited in an autosomal recessive inheritance pattern or thyroid dysgenesis (TD), whose inheritance pattern is controversial and whose mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c64f0942ea82b8d9b730a8e69a811eb
https://doi.org/10.1111/cen.14577

The genetic characteristics of congenital hypothyroidism in China by comprehensive screening of 21 candidate genes

Autor: Cui-Cui Guo, Xiao-Ping Ye, Yue-Yue Wan, Ke-Yi Song, Feng Sun, Bing Han, Guan-Qi Gao, Yu-Ru Ma, Wei Liu, gang Chen, Wen-Bin Zhu, Jun-Xiu Zhang, Chang-Yi Yang, Lele Zhang, Liu Yang, Qian-Yue Zhang, Man-Man Zhang, Huai-Dong Song, Shuang-Xia Zhao

Publikováno v: European Journal of Endocrinology

Objective Congenital hypothyroidism (CH), the most common neonatal metabolic disorder, is characterized by impaired neurodevelopment. Although several candidate genes have been associated with CH, comprehensive screening of causative genes has been l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ac83a697d3b2f3ff722062bcd22b7a
https://doi.org/10.1530/eje-17-1017

THE THERAPEUTIC EVALUATION AND MECHANISM ON TREATING BRONCHIAL HYPER-RESPONSIVENESS COUGH BY ZIYINQINGRE PRESCRIPTION

Autor: Ming hui Yang, Yi Liu, Jun xiu Zhang, Yin Zhang, Shao dan Li, Yi Xin Cui

Publikováno v: African Journal of Traditional, Complementary and Alternative Medicines; Vol 13, No 5 (2016); 190-194
African Journal of Traditional, Complementary, and Alternative Medicines

Objective: Discussing the effects of Ziyinqingre prescription on the level of airway resistance (Rrs), airway response threshold (Dmin), airway conductance (sGrs) and the level of inflammatory cytokines interleukin-4 (IL-4) and interferon-γ (IFN-γ)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2dfdec2084bc050fdac6aa1c3fcc03b
https://doi.org/10.21010/ajtcam.v13i5.25

Sesamin Ameliorates Advanced Glycation End Products-Induced Pancreatic β-Cell Dysfunction and Apoptosis

Autor: Li-qun Guo, Ru-Yuan Deng, Guo-dong Wang, Jie-ren Yang, Jun-xiu Zhang, Ming-zhe Ma, Qing Su, Xiang Kong

Publikováno v: Nutrients, Vol 7, Iss 6, Pp 4689-4704 (2015)
Nutrients
Volume 7
Issue 6
Pages 4689-4704

Advanced glycation end products (AGEs), the direct modulators of β-cells, have been shown to cause insulin-producing β-cell dysfunction and apoptosis through increase of intracellular reactive oxygen species (ROS) production. Sesamin has been demon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1d85521a039d7aa09f05267306decf
http://www.mdpi.com/2072-6643/7/6/4689