Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jun-nian Zheng"'
Autor:
Zhi-Ying Shao, Wen-Dong Yang, Hui Qiu, Zhi-Hong He, Meng-Ru Lu, Qi Shen, Jin Ding, Jun-Nian Zheng, Jin Bai
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-15 (2024)
Abstract Colorectal cancer (CRC) remains a significant global health issue with high incidence and mortality. Yin Yang 1 (YY1) is a powerful transcription factor that acts dual roles in gene activation and repression. High expression level of YY1 has
Externí odkaz:
https://doaj.org/article/1211c41ded5b44f7a681b28d002fb28e
Autor:
Bing-Qing Shang, Min-Le Li, Hao-yu Quan, Ping-Fu Hou, Zhong-Wei Li, Su-Fang Chu, Jun-Nian Zheng, Jin Bai
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-10 (2019)
Abstract Cancer has become a major health issue worldwide, contributing to a high mortality rate. Tumor metastasis is attributed to the death of most patients. Epithelial-to-mesenchymal transition (EMT) plays a vital role in inducing metastasis. Duri
Externí odkaz:
https://doaj.org/article/f75a58e7005d400bb923843442da530e
Autor:
Xin-Tian Chen, Zhong-Wei Li, Xue Zhao, Min-Le Li, Ping-Fu Hou, Su-Fang Chu, Jun-Nian Zheng, Jin Bai
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The kidney is vital in maintaining fluid, electrolyte, and acid–base balance. Kidney-related diseases, which are an increasing public health issue, can happen to people of any age and at any time. Circular RNAs (circRNAs) are endogenous RNA that ar
Externí odkaz:
https://doaj.org/article/aed94977eabc48eaa2444d8f5e3e0074
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e111920 (2014)
BACKGROUND: Malignant melanoma is the most aggressive and deadly form of skin cancer. Dacarbazine (DTIC) has been the approved first-line treatment for metastatic melanoma in routine clinical practice. However, response rates with single-agent DTIC a
Externí odkaz:
https://doaj.org/article/4536a574065c4021904b7cde71e1e3a6
4-(4-Chlorophenyl)-2,6-bis(1H-indol-3-yl)-1,4-dihydropyridine-3,5-dicarbonitrile ethanol monosolvate
Autor:
Song-Lei Zhu, Jun-Nian Zheng
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 5, Pp o1300-o1301 (2012)
In the title compound, C29H18ClN5·C2H6O, the dihydropyridine ring adopts a strongly flattened envelope conformation, with a maximum deviation of 0.139 (2) Å from its best plane for the Csp3 atom. The dihedral angles between the dihydropyridine ring
Externí odkaz:
https://doaj.org/article/c329681d3cc446ee8401d893bf07e018
Publikováno v:
Genomics. 114:110424
Serine hydroxymethyltransferase 2 (SHMT2) is the first rate-limiting enzyme for serine/glycine biosynthesis and one carbon metabolism. Here, we explore the underlying mechanism of how SHMT2 functions in renal cell carcinoma (RCC) initiation.In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2684439012ed50cab9d025fff0efac9
https://doi.org/10.1016/j.ygeno.2022.110424
https://doi.org/10.1016/j.ygeno.2022.110424
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 27(5)
To knockout ADRB2 gene rapidly and efficiently in human primary T cells by using CRISPR/Cas9 technology and multiple sgRNAs strategy.Six paired-sgRNAs, which were designed to target the 5' constitutive coding exons of ADRB2 gene, were cloned into pGL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b67b0b1f8565b6ddd33300cd78bdf8b6
https://pubmed.ncbi.nlm.nih.gov/31607332
https://pubmed.ncbi.nlm.nih.gov/31607332
Autor:
Rui Wang, Richard D. Ye, Jiahua Cui, Jun Nian Zheng, Ya xian Wu, Feng Qian, Gang Wang, Yao yao Yang, Qiong Wu, Hui Qiong He, Shaoshun Li, Yun juan Nie
Publikováno v:
Chemical Biology & Drug Design. 87:895-904
DMAKO-05((S)-1-((5E,8E)-5,8-bis(hydroxyimino)-1,4-dimethoxy-5,8-dihydronaphthalen-2-yl)-4-methylpent-3-enyl 3-methylbutanoate) is a novel oxime derivative of shikonin, the major component extracted from Chinese herb Lithospermun erythrorhizon. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0188b50fa7be5d60915c60fe8bf615ac
https://doi.org/10.1111/cbdd.12722
https://doi.org/10.1111/cbdd.12722
Autor:
Ding-Guo Zhang1 davidzhang1104@gmail.com, Jun-Nian Zheng1,2 jnzheng@xzmc.edu.cn, Dong-Sheng Pei1 dspei@xzmc.edu.cn
Publikováno v:
Molecular Cancer. 2014, Vol. 13 Issue 1, p1-14. 14p. 1 Diagram.
Publikováno v:
Letters in Drug Design & Discovery. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71fbf50545bcdaa6aa8a867212ee04f6
https://doi.org/10.2174/1570180814666170306121357
https://doi.org/10.2174/1570180814666170306121357