Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jun-ichiro Suzuki"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Mastitis is an inflammatory disease affecting mammary tissues caused by bacterial infection that negatively affects milk quality and quantity. S-Allylmercaptocysteine (SAMC), a sulfur compound in aged garlic extract (AGE), suppresses lipopol
Externí odkaz:
https://doaj.org/article/872140e81fd84d84bb0e02b7776f3eb2
Autor:
Satomi Miki, Jun-ichiro Suzuki, Miyuki Takashima, Mari Ishida, Hiroki Kokubo, Masao Yoshizumi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Atherosclerosis is a chronic inflammatory disease that may lead to the development of serious cardiovascular diseases. Aged garlic extract (AGE) has been reported to ameliorate atherosclerosis, although its mode of action remains unclear. We
Externí odkaz:
https://doaj.org/article/021dfad5244f4d6cab3bb0b09c4f73c9
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Vascular endothelial barrier function is maintained by cell-to-cell junctional proteins and contributes to vascular homeostasis. Various risk factors such as inflammation disrupt barrier function through down-regulation of these p
Externí odkaz:
https://doaj.org/article/37d809f4e5b74f42a149e70474f2c517
Publikováno v:
Molecules, Vol 22, Iss 4, p 570 (2017)
S-1-Propenyl-ʟ-cysteine (S1PC) is a stereoisomer of S-1-Propenyl-ʟ-cysteine (SAC), an important sulfur-containing amino acid that plays a role for the beneficial pharmacological effects of aged garlic extract (AGE). The existence of S1PC in garlic
Externí odkaz:
https://doaj.org/article/22e6646ec1d044899e1cac9b1c14e236
Autor:
Jun-ichiro Suzuki, Mari Ishida, Hiroki Kokubo, Miyuki Takashima, Satomi Miki, Masao Yoshizumi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Atherosclerosis is a chronic inflammatory disease that may lead to the development of serious cardiovascular diseases. Aged garlic extract (AGE) has been reported to ameliorate atherosclerosis, although its mode of action remains unclear. We found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3800fdfb19dbb3ac489040e8d6c53ea
https://doaj.org/article/021dfad5244f4d6cab3bb0b09c4f73c9
https://doaj.org/article/021dfad5244f4d6cab3bb0b09c4f73c9
Publikováno v:
Experimental and Therapeutic Medicine
Aged garlic extract (AGE) has been shown to improve peripheral circulatory disturbances in both clinical trials and experimental animal models. To investigate the effect of S-1-propenylcysteine (S1PC), a characteristic sulfur compound in AGE, on cold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc624e427798c9c9d9d36d0598ec0003
http://europepmc.org/articles/PMC7401927
http://europepmc.org/articles/PMC7401927
Additional file 6: Figure S6. Effects of GEF-H1 knockdown on downstream signaling of TNF-α, RhoA and Rac, in HUVECs. Effects of GEF-H1 knockdown on TNF-α-induced MLC2 phosphorylation (a), MYPT phosphorylation (b), ERK1/2 phosphorylation (c) and MLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da25a5e79fb9cc65ae58af1276830da
Additional file 3: Figure S3. Effects of S1PC on protein levels of TNF receptors and TRAF2 in HUVECs. a Effects of S1PC on the protein levels of TNFR1 and TNFR2 in HUVECs. The membrane and cytoplasmic proteins were extracted after the stimulation wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681dc29c54db43c9de5cd23d081a6786
Additional file 5: Figure S5. Effects of S1PC on the cell proliferation and morphology of HUVECs. a Effect of S1PC on the cell proliferation in HUVECs. Cell viability was measured with cell proliferation assay system after the treatment with S1PC (75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d5c205f8abe356127d6fc38df09b22
Additional file 1: Figure S1. Effects of AGE and its major sulfur-constituents on TNF-α-induced hyperpermeability of HUVECs. a The concentration-dependent effect of AGE on TNF-α-induced hyperpermeability of HUVECs. Vascular permeability assay was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946813eabe887e33164c4e9bcfc0206b