Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jun-ichi Yasuoka"'
Autor:
Jun-Ichi Yasuoka, Yoshihiro Sasaki, Yuko T. Sato, Shin-ichi Sawada, Kazunari Akiyoshi, Riku Kawasaki, Ryosuke Mizuta
Publikováno v:
Biomaterials Science. 8:619-630
Surface polymer engineering was applied with a carrier of exosomes, namely, the amphiphilic cationic CHP (cCHP) nanogel, to improve the delivery of exosome content by forming complexes with the exosomes. Mouse macrophage cells were used to produce th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c03bc9791b4627eb075c6d0393225c5
https://doi.org/10.1039/c9bm01232j
https://doi.org/10.1039/c9bm01232j
Autor:
Shoichi Kusumoto, Yoshimasa Imamura, Toshihide Tamura, Masahito Hashimoto, Jun-ichi Yasuoka, Yasuo Suda, Shozo Kotani, Kazue Aoyama
Publikováno v:
Polymeric Drugs and Drug Delivery Systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3405bc839fd12062fccd714cb0050381
https://doi.org/10.1201/9780429136405-14
https://doi.org/10.1201/9780429136405-14
Publikováno v:
Biomaterials Science. 3:256-264
Unmethylated CpG oligodeoxynucleotides induce inflammatory immune responses through cytokine production and have attracted increasing attention as an immunostimulator. However, there remains a challenging issue of the use of 'native CpG DNA'. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9d7266f2b82dec37191b93a8f291ad
https://doi.org/10.1039/c4bm00293h
https://doi.org/10.1039/c4bm00293h
Autor:
Kazunari Akiyoshi, Toshikazu Bando, Gengo Kashiwazaki, Jun-ichi Yasuoka, Tomofumi Yoshidome, Toshiki Takagaki, Hiroshi Sugiyama, Seiji Masui, Kaori Hashiya, Ganesh N. Pandian
Publikováno v:
Journal of Medicinal Chemistry. 55:2057-2066
Four new alkylating N-methylpyrrole-N-methylimidazole (PI) polyamide conjugates (1-4) with seven-base-pair (bp) recognition ability were synthesized. Evaluation of their DNA-alkylating activity clearly showed accurate alkylation at match site(s). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ebf02948f2df1a0cb8d4edc9ad077dd
https://doi.org/10.1021/jm201225z
https://doi.org/10.1021/jm201225z
Autor:
Jun-ichi Yasuoka, Shoichi Kusumoto, Yoshimasa Imamura, Shozo Kotani, Masahito Hashimoto, Yasuo Suda
Publikováno v:
Glycoconjugate Journal. 16:213-221
Previously, we showed that quantitatively minor several glycolipids only less than 5% of the lipoteichoic acid (LTA) fraction from Enterococcus hirae ATCC 9790 possessed cytokine-inducing activity, whereas the major component (over 90%) did not [Suda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7d6e3f4ff2b1454908474ea9baacb13
https://doi.org/10.1023/a:1007076304254
https://doi.org/10.1023/a:1007076304254
Autor:
Yuko Nobe, Tateaki Wakamiya, Shoichi Kusumoto, Seiki Kuramitsu, Shinichi Kawaguchi, Jun-ichi Yasuoka
Publikováno v:
Journal of Biochemistry. 122:55-63
The mechanism of recognition of hydrophobic substrates was investigated using Escherichia coli aspartate aminotransferase (AspAT), E. coli aromatic amino acid aminotransferase (AroAT), and their chimeric enzyme (DY18). Surprisingly, broad substrate s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8f4d70e2ddf4f357714d61c9cc7cb7
https://doi.org/10.1093/oxfordjournals.jbchem.a021740
https://doi.org/10.1093/oxfordjournals.jbchem.a021740
Autor:
Takeshi Yoshida, Shoichi Kusumoto, Yasuo Suda, Jun Ichi Yasuoka, Shozo Kotani, Masahito Hashimoto, Haruhiko Takada
Publikováno v:
Journal of Biochemistry. 121:779-786
Previously, lipoteichoic acid (LTA) of Enterococcus hirae was found to exhibit definite cytokine-inducing activity but synthetic specimens which share the fundamental structural principles proposed for LTA had no corresponding activity. We also showe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04925257ea141e83c99c99a33626bbb8
https://doi.org/10.1093/oxfordjournals.jbchem.a021653
https://doi.org/10.1093/oxfordjournals.jbchem.a021653
Autor:
Shoichi Kusumoto, Raphael M. Ottenbrite, Jun-ichi Yasuoka, Masahito Hashimoto, Jian L. Ding, Yasuo Suda, Naoto Oku
Publikováno v:
Journal of Bioactive and Compatible Polymers. 11:100-109
In order to confirm the immuno-stimulating activity of fractionated and hydrophobized poly(maleic acid-alt-7,12-dioxaspiro-[5,61-dodec-9-ene) [poly(MA-CDA)], we evaluated exo-vivo cytokine inducing activity of the polymers using peripheral whole bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60baf1311354c2dc5ff8bead0f7f43ba
https://doi.org/10.1177/088391159601100202
https://doi.org/10.1177/088391159601100202
Autor:
Tateaki Wakamiya, Shoichi Kusumoto, Kunio Saruta, Jun-ichi Yasuoka, Ryusaku Togashi, Takatoshi Nishida
Publikováno v:
Bulletin of the Chemical Society of Japan. 69:465-468
Nα-Fmoc-O-[(benzyloxy)hydroxyphosphinyl]serine and Nα-Fmoc-O-[(benzyloxy)hydroxyphosphinyl]threonine were prepared in order to be utilized for the synthesis of phosphoserine- or phosphothreonine-containing peptides based on the Fmoc-mode pre-phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5a0e70b7241a47ba7d1148cdd5def35
https://doi.org/10.1246/bcsj.69.465
https://doi.org/10.1246/bcsj.69.465
Publikováno v:
Bulletin of the Chemical Society of Japan. 68:2699-2703
Boc-phosphoamino acid derivatives with O-[di(4-nitrobenzyl)- or dicyclohexylphosphono]-protection were prepared for application to the Boc-mode solid-phase synthesis of phosphopeptides. These protecting groups are both stable to TFA, but removable wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cad4d89277f061fa65c6f5f6c295f40
https://doi.org/10.1246/bcsj.68.2699
https://doi.org/10.1246/bcsj.68.2699