Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jun-ichi Yasumoto"'
Autor:
Atsuhisa Kajiwara, Tadaaki Kirita, Yuichiro Imai, Takeo Ohnishi, Nobuhiro Yamakawa, Ken Ohnishi, Jun-ichi Yasumoto, Akihisa Takahashi
Publikováno v:
Oral Oncology. 41:631-636
Radiotherapy for oral squamous cell carcinomas is limited in its efficacy and in its ability to improve the survival rate in patients at an advanced stage. A protocol is described here which may elevate the therapeutic efficacy of radiation for these
Autor:
Shigeru Tatebayashi, M. Maeda, Atsuhisa Kajihara, Masahide Inoue, Chitta Ranjan Choudhury, Tadaaki Kirita, Jun-ichi Yasumoto
Publikováno v:
International Journal of Oral and Maxillofacial Surgery. 34:324-327
A rare case of untreated tongue carcinoma survived for 15 years is presented. A 43-year-old Japanese woman was referred to our department with a 1.8 cm × 1.0 cm white and red non-indurated lesion of the left border of the tongue. The histological ex
Autor:
Takeo Ohnishi, Eiichiro Mori, Kosuke Nagayama, Hideki Matsumoto, Akihisa Takahashi, Hidenori Tanaka, Ken Ohnishi, Nobuhiro Yamakawa, Sayako Hirose, Kazue Yuki, Mutsuko Kitano, Jun-ichi Yasumoto
Publikováno v:
Cancer Research. 64:8839-8845
To identify critical events associated with heat-induced cell killing, we examined foci formation of γH2AX (histone H2AX phosphorylated at serine 139) in heat-treated cells. This assay is known to be quite sensitive and a specific indicator for the
Publikováno v:
Journal of Health Science. 49:273-277
In recent years, cancer-related genes have been analyzed at the molecular level as predictive indicators for cancer therapy. Among those genes, the tumor suppressor gene p53 is worthy of notice in cancer therapy, because the p53 molecule prevents the
Autor:
Akihisa Takahashi, Takeo Ohnishi, Tadaaki Kirita, Ken Ohnishi, Kazue Yuki, Yuichiro Imai, Jun-ichi Yasumoto
Publikováno v:
Journal of Radiation Research. 44:41-45
Mutations in the p53 tumor suppressor gene have recently been reported to have an impact on clinical trials of several human tumors, including head and neck cancers. To confirm the p53-dependence of X-ray induced apoptosis, we used two cell lines der
Autor:
K. Yamamoto, Jun-ichi Yasumoto, Tadaaki Kirita, Masayoshi Kawakami, Yuichiro Imai, Kazuhiko Ohgi
Publikováno v:
Journal of Japan Society for Oral Tumors. 15:7-12
今回われわれは診断後, 約3か月の臨床経過中に完全に自然消失した上顎歯肉原発悪性リンパ腫の1例を纖したので, その概要を報告する。症例は80歳女性で, 右側上顎臼歯部の腫脹を主訴に
Autor:
Tadaaki Kirita, Ken Ohnishi, Atsuhisa Kajihara, Nobuhiro Yamakawa, Yuichiro Imai, Akihisa Takahashi, Takeo Ohnishi, Jun-ichi Yasumoto
Publikováno v:
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 24(8)
Hyperthermia is useful in the treatment of human head and neck cancers, because it is relatively easy to regulate temperatures when compared to tumors located in deep organs. In this study, attention was focused on p53 as a possible predictive indica
Publikováno v:
International journal of oncology. 29(1)
The aim of this study was to ascertain whether LY294002, an inhibitor of PI-3K, enhances heat sensitivity in human cancer cells regardless of their p53 status. Colony formation assays showed that LY294002 enhanced heat sensitivity in two human lung c
Autor:
Akihisa Takahashi, Jun-ichi Yasumoto, Hiroshi Hosoi, Katsunari Yane, Noritomo Okamoto, Kazue Yuki, Ken Ohnishi, Takeo Ohnishi, Ichiro Ota, Hirokazu Kanata
Publikováno v:
Apoptosis : an international journal on programmed cell death. 9(6)
To clarify effective chemotherapeutic regimens against cancer, we examined the effects of glycerol on apoptosis induced by CDDP treatment using cultured human cancer cells (in vitro) and transplanted tumor in mice (in vivo). Human tongue cell carcino
Autor:
Hirokazu Kanata, Hiroshi Hosoi, Katsunari Yane, Ken Ohnishi, Kazue Yuki, Akihisa Takahashi, Jun-ichi Yasumoto, Takeo Ohnishi, Ichiro Ota
Publikováno v:
Scopus-Elsevier
To increase the chemo-sensitivity of anaplastic thyroid carcinoma, we examined the effects of glycerol on the tumor growth after CDDP treatment. The cultured cells of an anaplastic thyroid carcinoma cell line (8305c) carrying a mutated p53 gene (mp53