Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Jun-ichi Niwa"'
Autor:
Muhammad Irfanur Rashid, Takuji Ito, Fuyuki Miya, Daisuke Shimojo, Kanae Arimoto, Kazunari Onodera, Rina Okada, Takunori Nagashima, Kazuki Yamamoto, Zohora Khatun, Rayhanul Islam Shimul, Jun-ichi Niwa, Masahisa Katsuno, Gen Sobue, Hideyuki Okano, Hidetoshi Sakurai, Kazunori Shimizu, Manabu Doyu, Yohei Okada
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract Pathophysiological analysis and drug discovery targeting human diseases require disease models that suitably recapitulate patient pathology. Disease-specific human induced pluripotent stem cells (hiPSCs) differentiated into affected cell typ
Externí odkaz:
https://doaj.org/article/b86903a1ae624984930cf68c5276e193
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Calcified amorphous tumor (CAT) of the heart is a rare non-neoplastic intracardiac mass, a calcium deposition surrounded by amorphous fibrous tissue, and possibly causes cerebral embolism. Even rarer is CAT associated with infecti
Externí odkaz:
https://doaj.org/article/c830e75017964ae68e0001b8acae3aee
Publikováno v:
Vaccines, Vol 10, Iss 6, p 935 (2022)
Rhabdomyolysis is a well-known clinical syndrome of muscle injury. Rhabdomyolysis following coronavirus disease 2019 (COVID-19) vaccination has recently been reported. The patients’ weakness gradually subsided and did not recur. Rhabdomyolysis asso
Externí odkaz:
https://doaj.org/article/e1d74f3bf4ae4340a772ae38199de743
Autor:
Soutarou Taguchi, Hirofumi Koide, Hiroko Oiwa, Miku Hayashi, Kazuhiro Ogawa, Chihiro Ito, Koji Nakashima, Tomoko Yuasa, Akihiro Yasumoto, Hiroaki Ando, Akifumi Fujikake, Takaaki Fukuoka, Keisuke Tokui, Masayuki Izumi, Yuka Tsunoda, Yuichi Kawagashira, Yohei Okada, Jun-Ichi Niwa, Manabu Doyu
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255274 (2021)
ObjectiveTo clarify whether antiparkinsonian drugs contribute to nocturnal sleep disturbances in patients with Parkinson's disease (PD).BackgroundAlthough the major antiparkinsonian drugs L-dopa and dopamine agonists (DAs) have been found to affect s
Externí odkaz:
https://doaj.org/article/e8ffd43dcce34cb4b784d0d96a8bc379
Publikováno v:
Parkinson's Disease, Vol 2019 (2019)
Little is known about the relationship between regional cerebral blood flow (rCBF) change and clinical improvement in patients with Parkinson’s disease (PD). Single-photon emission computed tomography (SPECT) measurement of cerebral blood flow allo
Externí odkaz:
https://doaj.org/article/b15423f1784c4718969ea31fddeb3f55
Autor:
Yohei Iguchi, Masahisa Katsuno, Shinnosuke Takagi, Shinsuke Ishigaki, Jun-ichi Niwa, Masato Hasegawa, Fumiaki Tanaka, Gen Sobue
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 3, Pp 862-870 (2012)
TAR DNA-binding protein 43 (TDP-43) is a major component of ubiquitin-positive inclusion of TDP-43 proteinopathies including amyotrophic lateral sclerosis and frontotemporal lobar degeneration with ubiquitinated inclusions, which is now referred to a
Externí odkaz:
https://doaj.org/article/9e18ce3fe4114b4ab59ceb834cbaf63e
Autor:
Shinsuke Ishigaki, Jun-ichi Niwa, Shin-ichi Yamada, Miho Takahashi, Takashi Ito, Jun Sone, Manabu Doyu, Fumihiko Urano, Gen Sobue
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 2, Pp 331-341 (2007)
The ubiquitin–proteasome system (UPS) is involved in the pathogenetic mechanisms of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS). Dorfin is a ubiquitin ligase (E3) that degrades mutant SOD1 proteins, which are responsi
Externí odkaz:
https://doaj.org/article/40c04d8ac0f24df59d4535a3574584c8
Autor:
Shinnosuke Takagi, Yohei Iguchi, Masahisa Katsuno, Shinsuke Ishigaki, Kensuke Ikenaka, Yusuke Fujioka, Daiyu Honda, Jun-ichi Niwa, Fumiaki Tanaka, Hirohisa Watanabe, Hiroaki Adachi, Gen Sobue
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66966 (2013)
Phosphorylated and truncated TAR DNA-binding protein-43 (TDP-43) is a major component of ubiquitinated cytoplasmic inclusions in neuronal and glial cells of two TDP-43 proteinopathies, amyotrophic lateral sclerosis and frontotemporal lobar degenerati
Externí odkaz:
https://doaj.org/article/ebc148cf5fc94094b9e0021a172d8736
Autor:
Motoya Kimura, Yoshiteru Azuma, Soutarou Taguchi, Mizuki Takagi, Hiromitsu Mori, Yasuto Shimomura, Jun-Ichi Niwa, Manabu Doyu, Akihisa Okumura
Publikováno v:
Brain and Development. 44:343-346
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae0f2e520aa98e9e87bd1205911e0f7b
https://doi.org/10.1016/j.braindev.2022.01.003
https://doi.org/10.1016/j.braindev.2022.01.003
Publikováno v:
Haigan. 61:322-326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba3f3fff78644ba33ccc05d9f1cc494a
https://doi.org/10.2482/haigan.61.322
https://doi.org/10.2482/haigan.61.322