Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jun-ichi Akatsuka"'
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of growth factors that bind to and activate the EGF receptor (EGFR/ErbB1) and ErbB4. HB-EGF plays pivotal roles in pathophysiological processes, including cancer. Thus, mon
Autor:
Shozaburo Konishi, Yukihiro Takahashi, Sumio Miyazaki, Junichi Mimaya, Masashi Taki, Shigeru Ohta, Hiroji Okawa, Jun-ichi Akatsuka, Yasuo Horikoshi, Haruhiko Eguchi, Masahiro Sako, Shigeru Tsuchiya, Takashi Kaneko, Isao Sekine, Kohji Fujisawa, Eiichi Ishii, Fumio Bessho, Akira Shirahata
Publikováno v:
International Journal of Hematology. 83:29-38
A practice guideline aimed at standardizing the treatment for childhood idiopathic thrombocytopenic purpura (ITP) is presented. This consensus guideline is based on a survey carried out via a questionnaire prepared by the ITP Committee of the Japanes
Autor:
Kanji Sugita, Hideki Sasaki, Jun-ichi Akatsuka, Ichiro Tsukimoto, Nobuyuki Hamajima, Yukio Kiriyama, Hisato Kigasawa, Seiji Kojima, Jun Okamura, Shigeru Ohta, Akira Ohara, Masahiro Tsuchida, Shinsaku Imashuku
Publikováno v:
Blood. 90:1009-1013
The improved outcome of acquired aplastic anemia (AA) has revealed later complications, such as myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML). We retrospectively analyzed 167 children with severe acquired AA. Eleven of 50 childr
Autor:
K Fujisawa, Mitsuyoshi Urashima, Hiroshi Kobayashi, Kihei Maekawa, Hiroshi Uchiyama, Yasutaka Hoshi, M. Hurusato, Jun-ichi Akatsuka
Publikováno v:
Pediatrics International. 38:640-643
Morphological changes in the testis induced by chemotherapy given according to the Tokyo Children's Cancer Study Group (TCCSG) regimens were studied in children with acute lymphoblastic leukemia (ALL). After informed consent, testicular biopsies were
Autor:
Jun-ichi Akatsuka, Kojiro Yasunaga, Jyuzo Matsuda, Takeo Nomura, Atsushi Kuramoto, Shosaku Nomura, Nobuo Sakuragawa
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis. 2:213-218
TJ-137 administered to patients with chronic ITP increased the platelet count "slightly" or more in 31.7% of the patients and showed a clinical effect in 40.9% with a rating of "modestly effective" or better. With a low incidence of adverse reactions
Autor:
Takeo Nomura, Jun-ichi Akatsuka, Kingo Fujimura, Toshiro Takafuta, Atsushi Kuramoto, Tsukasa Abe, Tatsumi Uchida, Makoto Kawakita, Shin-ichiro Kuriya, Kiyoshi Kitamura, Kojiro Yasunaga
Publikováno v:
American Journal of Hematology. 51:37-44
The efficacy of recombinant human interferon alpha-2b (rh IFN alpha-2b) in the treatment of steroid resistant idiopathic thrombocytopenic purpura (ITP) was studied in 50 cases. Forty-one patients treated with rh IFN alpha-2b three times a week, six o
Autor:
Hiroyuki Shichino, Yoshiaki Tsuchida, Hideyuki Kito, Takashi Suzuki, Shoichi Koizumi, Morihiro Saeki, Junichi Mimaya, Isao Serine, Takahito Fujisawa, Atsushi Kikuta, Noboru Okada, Mutsuro Ohira, Motoaki Chin, Teruho Kajimoto, Masahiro Tanabe, Mitsumasa Iwata, Toshiaki Shimada, Kensuke Harada, Mayumi Takamura, Ikuo Okabe, Syunichi Kato, Jun-ichi Akatsuka, Ichiro Tsukimoto, Yoshiaki Tanaka, Masataka Ichikawa, Michio Kaneko, Jotaro Yokoyama, Takao Okamatsu, Takeo Fujimoto, Naomi Onuma, Hideo Mugishima, Eiichi Sanuki
Publikováno v:
Pediatrics International. 37:493-499
Encouraging results are reported with high-dose chemotherapy and total body irradiation followed by autologous bone marrow transplantation in the treatment of advanced neuroblastoma. However, relapse remains a significant problem. We used high-dose c
Autor:
M. Matsuzaki, J Ohnishi, C Kaihara, Jun-ichi Akatsuka, Masaharu Akiyama, Yoko Kato, Makoto Kamijo, Mitsuyoshi Urashima, Kihei Maekawa, Yasutaka Hoshi
Publikováno v:
Pediatrics International. 37:160-165
Ex vivo expansion of hematopoietic progenitor cells in the umbilical cord blood mononuclear cells (CB-MNC) was investigated in liquid culture system with various combinations of cytokines (stem cell factor [SCF], interleukin [IL]-3, IL-6, granulocyte
Autor:
Mitsuyoshi Urashima, Yasutaka Hoshi, Jun-ichi Akatsuka, Makoto Kamijo, Masaharu Akiyama, Yoko Kato, Kihei Maekawa, Akihiro Shishikura
Publikováno v:
Pediatrics International. 37:21-26
We compared the effects of various combinations of cytokines (stem cell factor [SCF], interleukin [IL]-3, IL-6, granulocyte-colony stimulating factor [G-CSF], erythropoietin [EPO]) among the growth of human hematopoietic progenitor cells from cord bl
Publikováno v:
Pediatric Hematology and Oncology. 12:1-18
Since January 1987, chemoprophylaxis and empiric therapy with antifungal drugs have been used routinely in neutropenic children with neoplasms. The incidence of terminal invasive fungal infection (IFI) diagnosed by autopsy findings is compared in two