Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jun-Yao Fan"'
Autor:
Ling-lin Kong, Wen Xie, Zi-yan Dong, Yue-ting Liu, Hui-Min Zhao, Jun-Yao Fan, Xiao-jing Qi, Jie Li
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background There are a variety of determinants that are key to functional disability of older adults. However, little is known regarding the relationship between cognitive frailty and disability among older people. The aims of this study wer
Externí odkaz:
https://doaj.org/article/b22556d46645465eb80242fd4030665f
Autor:
Jun-Yao Fan, Wen Xie, Wen-Ya Zhang, Yue-Ting Liu, Quan Wang, Hui-Min Zhao, Ling-Lin Kong, Jie Li
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Purpose The integral conceptual model of frailty (ICFM) integrates physical, psychological, social aspects of individuals and stresses that frailty is a dynamic state evolving over time. This study aimed to validate the ICMF among community-
Externí odkaz:
https://doaj.org/article/f97c4be9910142ff80805f152208c158
Publikováno v:
BMC Medical Education, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background The increasing of older adults has led to enormous demand for medical care. However, as a group with unique needs and characteristics, older adults are often discriminated against in the medical field. In this paper, we aimed to t
Externí odkaz:
https://doaj.org/article/0d777c10cba84c9d95d015b4a7769f0a
Autor:
Jun-Yao Fan, Wen Xie, Wen-Ya Zhang, Yue-Ting Liu, Quan Wang, Hui-Min Zhao, Ling-Lin Kong, Jie Li
Purpose The integral conceptual model of frailty (ICFM) integrates physical, psychological, social aspects of individuals and stresses that frailty is a dynamic state evolving over time. This study aimed to validate the ICMF among community-dwelling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff0a1432bae49d2b82ee54b8a91a81e2
https://doi.org/10.21203/rs.3.rs-2146813/v1
https://doi.org/10.21203/rs.3.rs-2146813/v1
Autor:
Quan Wang, Xin xue Xi, Yue ting Liu, Jun yao Fan, Ling lin Kong, Jing Mao, Jie Li, Huimin Zhao
Publikováno v:
Current Medical Science
Summary The outbreak of coronavirus disease 2019 (COVID-19) posed an unprecedented threat to health care providers (HCPs) in Wuhan, China, especially for nurses who were frequently exposed to infected or suspected patients. Limited information was av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807b5f1aabd0db5fdc7ebcc8735e060e
Publikováno v:
Molecular Biology Reports. 40:1685-1692
Aging and dysregulation of immune responds are closely associated through a complicated but unclear mechanism. Although many theories have been proposed as overall dysregulation involved in aging, mechanisms such as efficiency of DNA repairing, over-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cea6bb089c2f74c431bc2e5eeb13de9
https://doi.org/10.1007/s11033-012-2219-2
https://doi.org/10.1007/s11033-012-2219-2
Publikováno v:
Biochemistry. 34:11005-11016
Bizelesin (formerly U77,779, The Upjohn Co.) is a bifunctional DNA cross-linking antitumor antibiotic consisting of two open-ring homologs of the (+)-CC-1065 cyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one (CPI) subunits connected by a rigid linking moiet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb46df6b0d8999273b48a4de8988e2c
https://doi.org/10.1021/bi00035a006
https://doi.org/10.1021/bi00035a006
Publikováno v:
Chemico-Biological Interactions. 85:1-14
A series of 4-substituted aniline mustards ArNH(CH 2 ) n O p C 6 H 4 - N(CH 2 CH 2 Cl) 2 , where Ar is an acridine and n varies from 2 to 5, interact with DNA. Scatchard analysis shows the compounds bind tightly, with a binding site size similar to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2def96da919ce573bbee56a431c63423
https://doi.org/10.1016/0009-2797(92)90048-p
https://doi.org/10.1016/0009-2797(92)90048-p
Publikováno v:
Chemical research in toxicology. 12(12)
Two types of 9-anilinoacridine-linked mustards, containing aniline mustard side chains linked either at the 4-position of the intercalating acridine chromophore (type A) or at the 1'-position of the 9-anilino group (type B), were reacted with calf th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737a2ec18f80448050c064f700065b43
https://pubmed.ncbi.nlm.nih.gov/10604865
https://pubmed.ncbi.nlm.nih.gov/10604865
Publikováno v:
Journal of medicinal chemistry. 41(24)
A series of bis(hydroxymethyl)-substituted imidazoles, thioimidazoles, and pyrrolizines and related bis(carbamates), linked to either 9-anilinoacridine (intercalating) or 4-(4-quinolinylamino)benzamide (minor groove binding) carriers, were synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f846abe962c7f22e41895a9f12a6d83
https://pubmed.ncbi.nlm.nih.gov/9822545
https://pubmed.ncbi.nlm.nih.gov/9822545