Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Jun-Shen Huang"'
Autor:
Yu-Xi Li, Fu-Chao Chen, Ting Liu, Zhao-Peng Cai, Keng Chen, Guo-Xue Tang, Jun-Shen Huang, Xiang-Ge Liu, Jia-Jun Huang, Peng Wang, Yu-Wei Liang, Lin Huang
Publikováno v:
Stem Cells International, Vol 2020 (2020)
Bone remodeling is a process delicately balanced between osteoclastic bone resorption and osteoblastic bone formation. Osteoclasts (OCs) are multinucleated giant cells formed through the fusion of monocytic precursors of the hematopoietic stem cells
Externí odkaz:
https://doaj.org/article/f220d05f791a4382b96d691c7cbd9053
Autor:
Li-shu Zhang, Xunlei Kang, Jianming Lu, Yuannyu Zhang, Xiaofeng Wu, Guojin Wu, Junke Zheng, Rubina Tuladhar, Heping Shi, Qiaoling Wang, Lorraine Morlock, Huiyu Yao, Lily Jun-shen Huang, Pascal Maire, James Kim, Noelle Williams, Jian Xu, Chuo Chen, Cheng Cheng Zhang, Lawrence Lum
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 145-158 (2019)
Background: Chromosomal translocation-induced expression of the chromatin modifying oncofusion protein MLL-AF9 promotes acute myelocytic leukemia (AML). Whereas WNT/β-catenin signaling has previously been shown to support MLL-AF9-driven leukemogenes
Externí odkaz:
https://doaj.org/article/73d06b7f64ea44e7a85caf179ec3fdad
Autor:
Hsi-Hsien Hsieh, Huiyu Yao, Yue Ma, Yuannyu Zhang, Xue Xiao, Helen Stephens, Naureen Wajahat, Stephen S. Chung, Lin Xu, Jian Xu, Raajit K. Rampal, Lily Jun-shen Huang
Publikováno v:
Blood. 140:2371-2384
We found that in regenerative erythropoiesis, the erythroid progenitor landscape is reshaped, and a previously undescribed progenitor population with colony-forming unit-erythroid (CFU-E) activity (stress CFU-E [sCFU-E]) is expanded markedly to resto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd77add9490713ce8fccffcc5e98453b
https://doi.org/10.1182/blood.2022016741
https://doi.org/10.1182/blood.2022016741
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Type I and II cytokine receptors are cell surface sensors that bind cytokines in the extracellular environment and initiate intracellular signaling to control processes such as hematopoiesis, immune function, and cellular growth and development. One
Externí odkaz:
https://doaj.org/article/9af391f55bc14570817d6c865c1ad3b8
Autor:
Hsi-Hsien Hsieh, Huiyu Yao, Yue Ma, Yuannyu Zhang, Xue Xiao, Helen Stephens, Stephen S. Chung, Lin Xu, Jian Xu, Raajit K. Rampal, Lily Jun-shen Huang
We find that in regenerative erythropoiesis, the erythroid progenitor landscape is reshaped, and a previously undescribed progenitor population with CFU-E activity (stress CFU-E/sCFU-E) is markedly expanded to restore the erythron. sCFU-E are targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f63ba58e9a26bf03d444217bf66cd033
https://doi.org/10.1101/2022.06.27.497649
https://doi.org/10.1101/2022.06.27.497649
Autor:
Huiyu Yao, Junke Zheng, Li-shu Zhang, Lawrence G. Lum, Cheng Cheng Zhang, Lily Jun Shen Huang, Jianming Lu, Heping Shi, Noelle S. Williams, Pascal Maire, James Kim, Rubina Tuladhar, Lorraine Morlock, Chuo Chen, Xiaofeng Wu, Jian Xu, Xunlei Kang, Qiaoling Wang, Yuannyu Zhang, Guojin Wu
Publikováno v:
EBioMedicine
Background Chromosomal translocation-induced expression of the chromatin modifying oncofusion protein MLL-AF9 promotes acute myelocytic leukemia (AML). Whereas WNT/β-catenin signaling has previously been shown to support MLL-AF9-driven leukemogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06527c59cdc183ec9e77f7aa29ac8ad
https://doi.org/10.1016/j.ebiom.2018.11.039
https://doi.org/10.1016/j.ebiom.2018.11.039
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 4, p e1003022 (2013)
The Janus Kinase 2 (JAK2) plays essential roles in transmitting signals from multiple cytokine receptors, and constitutive activation of JAK2 results in hematopoietic disorders and oncogenesis. JAK2 kinase activity is negatively regulated by its pseu
Externí odkaz:
https://doaj.org/article/f1e01e537402430cbfda52ce21bb4408
Autor:
Zhenya Hong, Jane E. Craig, Taosheng Chen, Lily Jun Shen Huang, Wei Zhuang, Gamze B. Bulut, Sadie Miki Sakurada, Jonathan Low, Malia B. Potts, Jamshid Temirov, Joseph N. Miller, Raju R. Rayavarapu, Shondra M. Pruett-Miller
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Mitochondria are vital organelles that coordinate cellular energy homeostasis and have important roles in cell death. Therefore, the removal of damaged or excessive mitochondria is critical for maintaining proper cellular function. The PINK1-Parkin p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e35506dd5c5cc74f18ba5897b121cc5
https://pubmed.ncbi.nlm.nih.gov/33101709
https://pubmed.ncbi.nlm.nih.gov/33101709
Autor:
Lily Jun Shen Huang, James J. Bieker
Publikováno v:
Blood
Erythropoiesis is a complex multistage process that involves differentiation of early erythroid progenitors to enucleated mature red blood cells, in which lineage-specific transcription factors play essential roles. Erythroid Krüppel-like factor (EK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676615b48d8f852a4e595bdae6464796
https://pubmed.ncbi.nlm.nih.gov/32384137
https://pubmed.ncbi.nlm.nih.gov/32384137