Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jun-Ping Shiau"'
Autor:
Cheng-Che Wu, Mei-Ren Pan, Shen-Liang Shih, Jun-Ping Shiau, Chun-Chieh Wu, Shu-Jyuan Chang, Chieh-Ni Kao, Fang-Ming Chen, Ming-Feng Hou, Chi-Wen Luo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 163, Iss , Pp 114732- (2023)
Triple-negative breast cancer (TNBC) is characterized by the loss of expression of several biomarkers, which limits treatment strategies for the disease. In recent years, immunotherapy has shown promising results in the treatment of various tumors. E
Externí odkaz:
https://doaj.org/article/11e18ab5fac54dc59f444e1ffcc34b0b
Autor:
Jen-Yang Tang, Ya-Ting Chuang, Jun-Ping Shiau, Ching-Yu Yen, Fang-Rong Chang, Yi-Hong Tsai, Ammad Ahmad Farooqi, Hsueh-Wei Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12449 (2023)
Exosomes are cell-derived membranous structures primarily involved in the delivery of the payload to the recipient cells, and they play central roles in carcinogenesis and metastasis. Radiotherapy is a common cancer treatment that occasionally genera
Externí odkaz:
https://doaj.org/article/756c761d62ee49508832bf90360ff405
Autor:
Tzu-Jung Yu, Jun-Ping Shiau, Jen-Yang Tang, Ammad Ahmad Farooqi, Yuan-Bin Cheng, Ming-Feng Hou, Chia-Hung Yen, Hsueh-Wei Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8853 (2023)
Physalis plants are commonly used traditional medicinal herbs, and most of their extracts containing withanolides show anticancer effects. Physapruin A (PHA), a withanolide isolated from P. peruviana, shows antiproliferative effects on breast cancer
Externí odkaz:
https://doaj.org/article/b3b389f4a99c41c0bd499fce639ef0cf
Autor:
Min-Yu Lee, Jun-Ping Shiau, Jen-Yang Tang, Ming-Feng Hou, Phoebe Sussana Primus, Chai-Lin Kao, Yeun-Mun Choo, Hsueh-Wei Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7751 (2023)
Triple-negative breast cancer (TNBC) is insensitive to target therapy for non-TNBC and needs novel drug discovery. Extracts of the traditional herb Boesenbergia plant in Southern Asia exhibit anticancer effects and contain novel bioactive compounds b
Externí odkaz:
https://doaj.org/article/73017c79c7604c21a9457bfa9679ac6c
Autor:
Ya-Ting Chuang, Jun-Ping Shiau, Jen-Yang Tang, Ammad Ahmad Farooqi, Fang-Rong Chang, Yi-Hong Tsai, Ching-Yu Yen, Hsueh-Wei Chang
Publikováno v:
Cancers, Vol 15, Iss 8, p 2215 (2023)
Cancerous exosomes contain diverse biomolecules that regulate cancer progression. Modulating exosome biogenesis with clinical drugs has become an effective strategy for cancer therapy. Suppressing exosomal processing (assembly and secretion) may bloc
Externí odkaz:
https://doaj.org/article/ddcfdfbd6bae4638aca9d0e35107a99b
Autor:
Cheng-Yao Yang, Min-Yu Lee, Yeh-Long Chen, Jun-Ping Shiau, Yung-Hsiang Tsai, Chia-Ning Yang, Hsueh-Wei Chang, Chih-Hua Tseng
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6034 (2023)
A series of 4-anilinoquinolinylchalcone derivatives were synthesized and evaluated for antiproliferative activities against the growth of human cancer cell lines (Huh-7 and MDA-MB-231) and normal lung cells (MRC-5). The results exhibited low cytotoxi
Externí odkaz:
https://doaj.org/article/ae988e8775b542de966ef6b8755fd27d
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5741 (2023)
Ginger-derived compounds are abundant sources of anticancer natural products. However, the anticancer effects of (E)-3-hydroxy-1-(4′-hydroxy-3′,5′-dimethoxyphenyl)-tetradecan-6-en-5-one (3HDT) have not been examined. This study aims to assess t
Externí odkaz:
https://doaj.org/article/200b23df1c4f4a57862a50a6f7e9ca76
Autor:
Jun-Ping Shiau, Ya-Ting Chuang, Ching-Yu Yen, Fang-Rong Chang, Kun-Han Yang, Ming-Feng Hou, Jen-Yang Tang, Hsueh-Wei Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3688 (2023)
Many miRNAs are known to target the AKT serine-threonine kinase (AKT) pathway, which is critical for the regulation of several cell functions in cancer cell development. Many natural products exhibiting anticancer effects have been reported, but thei
Externí odkaz:
https://doaj.org/article/6f98736b7b144bf38ef89952303d25e3
Autor:
Sheng-Yao Peng, Jen-Yang Tang, Ting-Hsun Lan, Jun-Ping Shiau, Kuan-Liang Chen, Jiiang-Huei Jeng, Ching-Yu Yen, Hsueh-Wei Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3987 (2023)
Manoalide provides preferential antiproliferation of oral cancer but is non-cytotoxic to normal cells by modulating reactive oxygen species (ROS) and apoptosis. Although ROS interplays with endoplasmic reticulum (ER) stress and apoptosis, the influen
Externí odkaz:
https://doaj.org/article/fda9367a5a004f64bf691253f17c1520
Autor:
Ya-Ting Chuang, Jen-Yang Tang, Jun-Ping Shiau, Ching-Yu Yen, Fang-Rong Chang, Kun-Han Yang, Ming-Feng Hou, Ammad Ahmad Farooqi, Hsueh-Wei Chang
Publikováno v:
Cancers, Vol 15, Iss 1, p 318 (2023)
Cancer-derived exosomes exhibit sophisticated functions, such as proliferation, apoptosis, migration, resistance, and tumor microenvironment changes. Several clinical drugs modulate these exosome functions, but the impacts of natural products are not
Externí odkaz:
https://doaj.org/article/bb674d4012e14e14a8f70f0335a41fdb