Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Jun-Ming Liao"'
Autor:
Ziling Fang, Bo Cao, Jun-Ming Liao, Jun Deng, Kevin D Plummer, Peng Liao, Tao Liu, Wensheng Zhang, Kun Zhang, Li Li, David Margolin, Shelya X Zeng, Jianping Xiong, Hua Lu
Publikováno v:
eLife, Vol 7 (2018)
Ribosomal proteins (RPs) play important roles in modulating the MDM2-p53 pathway. However, less is known about the upstream regulators of the RPs. Here, we identify SPIN1 (Spindlin 1) as a novel binding partner of human RPL5/uL18 that is important fo
Externí odkaz:
https://doaj.org/article/2318789eb2a14269b8a96a4ddc9cb9b1
Autor:
Bo Cao, Kebing Wang, Jun-Ming Liao, Xiang Zhou, Peng Liao, Shelya X Zeng, Meifang He, Lianzhou Chen, Yulong He, Wen Li, Hua Lu
Publikováno v:
eLife, Vol 5 (2016)
Increasing evidence highlights the important roles of microRNAs in mediating p53’s tumor suppression functions. Here, we report miR-139-5p as another new p53 microRNA target. p53 induced the transcription of miR-139-5p, which in turn suppressed the
Externí odkaz:
https://doaj.org/article/bfaecc957e004174850341f777291784
Autor:
Hua Lu, Sarit Larisch, Shelya X. Zeng, Jun-Ming Liao, Yu Gan, Jiaxiang Chen, Qian Hao, Yingdan Huang, Xiang Zhou
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 2, Pp 1-11 (2021)
Cell Death and Disease, Vol 12, Iss 2, Pp 1-11 (2021)
Apoptosis related protein in TGF-β signaling pathway (ARTS) was originally discovered in cells undergoing apoptosis in response to TGF-β, but ARTS also acts downstream of many other apoptotic stimuli. ARTS induces apoptosis by antagonizing the anti
Autor:
Yingdan Huang, Hua Lu, Qian Hao, Xiang Zhou, Shelya X. Zeng, Jiaxiang Chen, Jun-Ming Liao, Sarit Larisch
Apoptosis Related protein in TGF-β Signaling pathway (ARTS) was originally discovered in cells undergoing apoptosis in response to TGF-β, but ARTS also acts downstream of many other apoptotic stimuli. ARTS induces apoptosis by antagonizing the anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84afb3a5bf71609142bd44bcc77e067d
https://doi.org/10.1101/2020.05.14.096982
https://doi.org/10.1101/2020.05.14.096982
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52172 (2012)
Previously, we reported that Inauhzin (INZ) induces p53 activity and suppresses tumor growth by inhibiting Sirt1. However, it remains unknown whether INZ may globally affect p53-dependent gene expression or not. Herein, we have conducted microarray a
Externí odkaz:
https://doaj.org/article/3deccde566704fa18e9d11aa5688de09
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21929 (2011)
BACKGROUND: Ras protein, as one of intracellular signal switches, plays various roles in several cell activities such as differentiation and proliferation. There is considerable evidence showing that calmodulin (CaM) binds to K-RasB and dissociates K
Externí odkaz:
https://doaj.org/article/62161c798eb1408f859405534fe36c8a
Autor:
Tao Liu, Hua Lu, Kun Zhang, Jun-Ming Liao, Shelya X. Zeng, Jianping Xiong, David Margolin, Bo Cao, Jun Deng, Wensheng Zhang, Peng Liao, Ziling Fang, Li Li, Kevin D Plummer
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Ribosomal proteins (RPs) play important roles in modulating the MDM2-p53 pathway. However, less is known about the upstream regulators of the RPs. Here, we identify SPIN1 (Spindlin 1) as a novel binding partner of human RPL5/uL18 that is important fo
Autor:
Wensheng Zhang, Bo Cao, Kun Zhang, David Margolin, Hua Lu, Ziling Fang, Tao Liu, Shelya X. Zeng, Jun-Ming Liao, Li Li, Jianping Xiong, Jun Deng, Peng Liao, Kevin D Plummer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd960befca6b3095d51db15735b7e7d
https://doi.org/10.7554/elife.31275.023
https://doi.org/10.7554/elife.31275.023
Publikováno v:
Journal of Molecular Cell Biology. 7:92-104
Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins h
Autor:
Jun-Ming Liao, Shelya Zeng, Sung-Hoon Kim, Daniel Nguyen, Qian Hao, Bo Cao, Xiang Zhou, Ji Hoon Jung, Hua Lu, Qi Zhang
Publikováno v:
Cancer Biology & Therapy. 16:412-419
Oncogene MYC is deregulated in many human cancers, especially in lymphoma. Previously, we showed that inauhzin (INZ) activates p53 and inhibits tumor growth. However, whether INZ could suppress cancer cell growth independently of p53 activity is stil