Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jun-Lin Yu"'
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 6, Iss 2, Pp 583-585 (2021)
Adonis amurensis Regel et Radde is an important cardiac folk medicinal plant which endemic to Northeast Asia. We determined the first complete chloroplast genome of A. amurensis using genome skimming approach. The cp genome was 157,032 bp long, with
Externí odkaz:
https://doaj.org/article/c17e189eaefb47898c632f15e98a4da0
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 4, Iss 2, Pp 3558-3559 (2019)
Prunus pensylvanica is one of the two native cherry species of North America. We determined the first complete chloroplast genome of P. pensylvanica using genome-skimming approach. The cp genome was 157,953 bp long, with a large single-copy region (L
Externí odkaz:
https://doaj.org/article/e5291ef6b2d04e429448b045c4c8e92e
Publikováno v:
Nucleic Acids Research. 51:D593-D602
Metalloenzymes are attractive research targets in fields of chemistry, biology, and medicine. Given that metalloenzymes can manifest conservation of metal-coordination and ligand binding modes, the excavation and expansion of metalloenzyme-specific k
Autor:
Guo-Bo Li, Gen Li, Ji Deng, Yang Lingling, Yu-Hang Yan, Xiang-Li Ning, Jun-Lin Yu, Qing-Qing Dai
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1931-1946 (2021)
We herein describe AncPhore, a versatile tool for drug discovery, which is characterized by pharmacophore feature analysis and anchor pharmacophore (i.e., most important pharmacophore features) steered molecular fitting and virtual screening. Compara
Publikováno v:
Ying yong sheng tai xue bao = The journal of applied ecology. 33(5)
The study of short-term dynamics of soil moisture in the dry-hot valley area during rainfall process will help identify soil hydrological function. In this study, we analyzed the short-term responses of soil moisture to rainfall in Huajiang dry-hot v
Autor:
Gen Li, Xiao-Pan Chen, Yu-Hang Yan, Ji Deng, Jürgen Brem, Christopher J. Schofield, You-Cai Xiao, Kai-Rong Zhu, Guo-Bo Li, Fener Chen, Jun-Lin Yu
Publikováno v:
Chemical Communications (Cambridge, England)
Chiral 3-substituted benzoxaboroles were designed as carbapenemase inhibitors and efficiently synthesised via asymmetric Morita–Baylis–Hillman reaction. Some of the benzoxaboroles were potent inhibitors of clinically relevant carbapenemases and r
Publikováno v:
Journal of medicinal chemistry. 64(24)
Metalloenzymes have critical roles in a wide range of biological processes and are directly involved in many human diseases; hence, they are considered as important targets for therapeutic intervention. The specific characteristics of metal ion(s)-co
Publikováno v:
Drug discovery today. 27(7)
Drug repositioning is an attractive strategy for discovering new therapeutic uses for approved or investigational drugs, with potentially shorter development timelines and lower development costs. Various computational methods have been used in drug
Autor:
Yong Wu, Ji Deng, Si-Yao Wang, Zong-Yuan Luo, Yali Ren, Yu-Xiang Wu, Cui Huo, Kai-Rong Zhu, Cheng Gao, Guo-Bo Li, Xiang-Li Ning, Jun-Lin Yu, Chen Yang, Shan Qian, Miao Wang, Gen Li, Zhouyu Wang, Cheng Peng, Yang Lingling, Yuzhi Li
Publikováno v:
Journal of medicinal chemistry. 64(12)
Human indoleamine 2,3-dioxygenase 1 (hIDO1) and tryptophan 2,3-dioxygenase (hTDO) have been closely linked to the pathogenesis of Parkinson's disease (PD); nevertheless, development of dual hIDO1 and hTDO inhibitors to evaluate their potential effica
Autor:
Xiang-Li Ning, Zhao-Feng Li, Yubin Luo, Zhenling Wang, Guo Li, You-Cai Xiao, Ji Deng, Yu-Hang Yan, Jun-Lin Yu, Guo-Bo Li
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 41:127956
The production of β-lactamases represents the main cause of resistance to clinically important β-lactam antibiotics. Boron containing compounds have been demonstrated as promising broad-spectrum β-lactamase inhibitors to combat β-lactam resistanc