Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jun-Lin Jiang"'
Publikováno v:
European Journal of Pharmacology. 854:54-61
Fibrosis is a reparative process with very few therapeutic options to prevent its progression to organ dysfunction. Chronic fibrotic diseases contribute to an estimated 45% of all death in the industrialized world. Asymmetric dimethylarginine (ADMA),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace16ce14cca216878165ed2b22bc169
https://doi.org/10.1016/j.ejphar.2019.03.055
https://doi.org/10.1016/j.ejphar.2019.03.055
Publikováno v:
Vascular Pharmacology. 108:46-56
Diabetic retinopathy (DR) is a leading cause of vision loss with retinal neovascularization. This study aims to investigate whether Asymmetric dimethylarginine (ADMA) impacts the pathogenesis of DR via focusing on promoting retinal neovascularization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef7ed2dd600f36326da8c984f64ed98
https://doi.org/10.1016/j.vph.2018.05.004
https://doi.org/10.1016/j.vph.2018.05.004
Autor:
Chu-Yi Huang, Mei-Ting Wu, Shuang-Yi He, Wei-Qiang Tong, Nian-Sheng Li, Jun-Lin Jiang, Li Yan, Bing-Xuan Niu, Ge Li, Xu Xie, Wei-Cheng Zhao
Publikováno v:
European Journal of Pharmacology. 908:174317
Endothelial cell dysfunction is a prominent feature of diabetic cardiovascular complications, and endothelial cell senescence is considered to be an important contributor to endothelial dysfunction. Discoidin domain receptor 1 (DDR1) has been reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb2eed02aa19f765358e63a171f6cf5
https://doi.org/10.1016/j.ejphar.2021.174317
https://doi.org/10.1016/j.ejphar.2021.174317
Autor:
Weifang Zhang, Jun-Lin Jiang, Xiao-Zhou Zou, Ting Liu, Chang-Ping Hu, Zhicheng Gong, Tian-Tian Zhu, Dai Li, Fang He
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 44:70-77
Background and objective Diabetic pulmonary fibrosis is a severe disease that increases mortality risk of diabetes. However, the molecular mechanisms leading to pulmonary fibrosis in diabetes are poorly understood. This study investigated the roles o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b544d6706e873640d18f105b834a027f
https://doi.org/10.1016/j.pupt.2017.03.012
https://doi.org/10.1016/j.pupt.2017.03.012
Publikováno v:
Amino acids. 51(10-12)
Blood–retinal barrier breakdown is the main pathological characteristics of diabetic retinopathy (DR). Asymmetric dimethylarginine (ADMA) was reported to be elevated in DR patients. In this study, we observed the dynamic profile of ADMA, retinal mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c930d1836cd7d1fbf2b947912762d628
https://pubmed.ncbi.nlm.nih.gov/31576457
https://pubmed.ncbi.nlm.nih.gov/31576457
Publikováno v:
Alcohol. 56:21-28
Numerous studies demonstrate that reactive aldehydes are highly toxic and aldehyde dehydrogenase 2 (ALDH2)-mediated detoxification of reactive aldehydes is thought as an endogenous protective mechanism against reactive aldehydes-induced cell injury.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5833e7161ad962549ac69cca54bb7489
https://doi.org/10.1016/j.alcohol.2016.10.004
https://doi.org/10.1016/j.alcohol.2016.10.004
Autor:
Jie-Jie Zhang, Lian-Sheng Li, Zhi-Chun Yang, Jun-Lin Jiang, Jun Peng, Qi-Lin Ma, Xiu-Ju Luo, Yan Wu, Ting-Bo Li, Wei-Qi Liu
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 21:536-548
Suppression of dimethylarginine dimethylaminohydrolase (DDAH) activation is related to endothelial dysfunction in hyperlipidemia, and nonmuscle myosin regulatory light chain (nmMLC20) has been show to exert transcriptional function in regulation of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f418c0b00159548aead6a5bf5cf7e02
https://doi.org/10.1177/1074248416634465
https://doi.org/10.1177/1074248416634465
Autor:
Xiu-Ju Luo, Qi Lin Ma, Qingjie Li, Yi Shuai Zhang, Nian Sheng Li, Yuan-Jian Li, Bin Liu, Jun Lin Jiang, Jie Jie Zhang, Jun Peng
Publikováno v:
Free Radical Biology and Medicine. 83:115-128
Nuclear myosin regulates gene transcription and this novel function might be modulated through phosphorylation of the myosin regulatory light chain (p-MLC20). Nonmuscle MLC20 (nmMLC20) is also present in the nuclei of cardiomyocytes and a potential n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d111fce1280e321bfc120151c91997
https://doi.org/10.1016/j.freeradbiomed.2015.02.013
https://doi.org/10.1016/j.freeradbiomed.2015.02.013
Autor:
Yong-Ping Bai, Qiong Yuan, Jun-Lin Jiang, Si-Yu Liu, Zhicheng Gong, Yuan-Jian Li, Chang-Ping Hu
Publikováno v:
Biochemical and Biophysical Research Communications. 458:869-876
The risk of cardiovascular complications in diabetic patients is mainly associated with endothelial dysfunction. Reduced number of EPCs and impaired function of EPCs in diabetes result in imbalance of endothelial homeostasis and dysfunction of vessel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3924761d3374672411264a426f47da10
https://doi.org/10.1016/j.bbrc.2015.02.050
https://doi.org/10.1016/j.bbrc.2015.02.050
Autor:
Bin Tan, Jun-Lin Jiang, Zheng Lou, Zhong-Bao Yang, Xiu-Ju Luo, Jie Yang, Jun Peng, Ting-Bo Li, Ying-Jun Zhou
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 387:861-871
Vitexin compound B-1 (VB-1) is a novel member of the vitexins family isolated from the seeds of the Chinese herb Vitex negundo. This study aims to investigate whether VB-1 is able to protect nerve cells against oxidative injury and whether the antiox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b3e1c3a06658212bd2b175b5acdfb2
https://doi.org/10.1007/s00210-014-1006-0
https://doi.org/10.1007/s00210-014-1006-0