Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jun-Kyu Byun"'
Autor:
Dong-Ho Kim, Yoo Na Kang, Jonghwa Jin, Mihyang Park, Daehoon Kim, Ghilsuk Yoon, Jae Won Yun, Jaebon Lee, Soo Young Park, Yu Rim Lee, Jun-Kyu Byun, Yeon-Kyung Choi, Keun-Gyu Park
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 5, Pp 1123-1136 (2024)
Abstract Tumor-associated macrophages (TAMs) are vital contributors to the growth, metastasis, and therapeutic resistance of various cancers, including hepatocellular carcinoma (HCC). However, the exact phenotype of TAMs and the mechanisms underlying
Externí odkaz:
https://doaj.org/article/df577a51f1824835a5fcc13bd4ed11d2
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 4, Pp 706-715 (2023)
Abstract Proliferating cancer cells rely largely on glutamine for survival and proliferation. Glutamine serves as a carbon source for the synthesis of lipids and metabolites via the TCA cycle, as well as a source of nitrogen for amino acid and nucleo
Externí odkaz:
https://doaj.org/article/616685740b4c403db12b174236862f38
Autor:
Hui-Jeon Jeon, Jun-Kyu Byun, Sang Bong Lee, Kwang Hee Son, Ji-Youn Lim, Da Sol Lee, Kil Soo Kim, Jin Woo Park, Gyeong Rim Shin, Ye Jin Kim, Jonghwa Jin, Daehoon Kim, Dong-Ho Kim, Ji Hoon Yu, Yeon-Kyung Choi, Keun-Gyu Park, Yong Hyun Jeon
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Background N-methyl-d-aspartate receptors (NMDARs) are considered to be involved in several physiological and pathophysiological processes in addition to the progression of neurological disorders. However, how NMDARs are involved in the glyc
Externí odkaz:
https://doaj.org/article/aca51ce4ef8844da84f54dee8bad840b
Autor:
Iljin Kim, Jieun Seo, Dong Hyun Lee, Yo-Han Kim, Jun-Hyung Kim, Myung-Bok Wie, Jun-Kyu Byun, Jang-Hyuk Yun
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Diabetic retinopathy (DR) is a disease that causes visual deficiency owing to vascular leakage or abnormal angiogenesis. Pericyte apoptosis is considered one of the main causes of vascular leakage in diabetic retina, but there are few known therapeut
Externí odkaz:
https://doaj.org/article/c4c6dfca5cac49a183107f458b38ebce
Autor:
Jun-Kyu Byun, Seunghyeong Lee, Gil Won Kang, Yu Rim Lee, Soo Young Park, Im-Sook Song, Jae Won Yun, Jaebon Lee, Yeon-Kyung Choi, Keun-Gyu Park
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-16 (2022)
Abstract Background Macropinocytosis, an important nutrient-scavenging pathway in certain cancer cells, allows cells to compensate for intracellular amino acid deficiency under nutrient-poor conditions. Ferroptosis caused by cysteine depletion plays
Externí odkaz:
https://doaj.org/article/62fdcafd44e94a9aaab7d63938468126
Autor:
Jun-Kyu Byun, Yeon-Kyung Choi, Ji-Hyun Kim, Ji Yun Jeong, Hui-Jeon Jeon, Mi-Kyung Kim, Ilseon Hwang, Shin-Yup Lee, You Mie Lee, In-Kyu Lee, Keun-Gyu Park
Publikováno v:
Cell Reports, Vol 20, Iss 3, Pp 586-599 (2017)
Proper regulation of mTORC1 and mTORC2 upon nutrient starvation is critical for cancer cell survival. Upregulation of Sestrin2 in response to glutamine deprivation rescues cell death by suppressing mTORC1. However, the contribution of mTORC2 to Sestr
Externí odkaz:
https://doaj.org/article/9515e654db7b4ff09beddd5322bcf9dd
Autor:
Seokmin Jeong, Jun-Kyu Byun, Sung Jin Cho, Jungwook Chin, In-Kyu Lee, Yeon-Kyung Choi, Keun-Gyu Park
Publikováno v:
Nutrients, Vol 10, Iss 11, p 1638 (2018)
Macropinocytosis is a regulated form of endocytosis that mediates the nonselective uptake of nutrients to support growth under nutrient-deprived conditions. KRAS-mutant cancer cells upregulate macropinocytosis to import extracellular proteins, which
Externí odkaz:
https://doaj.org/article/0a8031a1d79a4fc0b12013e6d12fbd55
Autor:
Jun-Kyu Byun, Sun Hee Lee, Eui Jung Moon, Myo-Hyeon Park, Hyeonha Jang, Douglas H. Weitzel, Hyun-Hwi Kim, Nikita Basnet, Do-Yeon Kwon, Chen-Ting Lee, Tesia N. Stephenson, Ji-Hak Jeong, Bhargav A. Patel, Sung Jean Park, Jen-Tsan Chi, Mark W. Dewhirst, Jiyong Hong, You Mie Lee
Publikováno v:
British Journal of Cancer. 128:1491-1502
Autor:
Seunghyeong Lee, Jun-Kyu Byun, Na-Young Kim, Jonghwa Jin, Hyein Woo, Yeon-Kyung Choi, Keun-Gyu Park
Publikováno v:
BMB Reports. 55:459-464
Publikováno v:
The Journal of biological chemistry. 298(9)
Faithful translation of the genetic code is critical for the viability of all living organisms. The trans-editing enzyme ProXp-ala prevents Pro to Ala mutations during translation by hydrolyzing misacylated Ala-tRNA