Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jun-Ichiro Yoshimitsu"'
Autor:
Kanji Takada, Jun-Ichiro Yoshimitsu, Yoshinori Ohashi, Keiji Shiroyama, Nobuyuki Sugioka, Yukako Ito
Publikováno v:
Journal of Controlled Release. 121:176-180
To ascertain the pharmacological activity of erythropoietin (EPO) administered by self-dissolving micropiles (SDMP), four kinds of EPO SDMPs were prepared and were administered to rats in 4 consecutive days at 200, 500, 1000 and 2300 IU/kg. After the
Publikováno v:
Journal of Drug Targeting. 14:255-261
Erythropoietin (EPO) loaded microneedles were prepared using thread-forming polymer as a base for the percutaneous administration of EPO. The used polymers were dextrin, chondroitin sulfate and albumin. Under room temperature, EPO solution was added
Autor:
Yukako Ito, Jun-Ichiro Yoshimitsu, Kanji Takada, Y Ohashi, Nobuhito Shibata, Natarajan Venkatesan, Nobuyuki Sugioka
Publikováno v:
International journal of pharmaceutics. 310(1-2)
Oral administration of mucoadhesive tablets containing erythropoietin (EPO) and an absorption enhancer Labrasol was studied in rats and dogs. Mucoadhesive tablets were prepared using Sylysia 550 holding the absorption enhancer and Carbopol 974P as a
Publikováno v:
Biomaterials. 26(34)
In the present study, an attempt was made to study the feasibility of nanoparticulate adsorbents in the presence of an absorption enhancer, as a drug delivery tool for the administration of erythropoietin (EPO) to the small intestine. Liquid filled n