Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Jun-Ichi Tanabe"'
1
Inflammatory cytokines modulate chemokine production patterns of HepG2 cells toward initially inclined direction
Autor: Tetsuya Ishikawa, Shinichi Kakumu, Ken Sato, Haruhisa Nakao, Tomohiko Ohashi, Akihiko Okumura, Jun-Ichi Tanabe, Minoru Ayada, Hiroyasu Ito, Teiji Kuzuya, Naoki Hotta, Masashi Yoneda
Publikováno v: Hepatology Research. 39:510-519
Aim Human hepatocytes are known to express an array of inflammatory cytokines and chemokines. In this study, we examined the potential roles of hepatocytes in regulating immune responses in the liver, by assessing the induction of Th1- or Th2-specifi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020f241325fd69d883407910e8cde956
https://doi.org/10.1111/j.1872-034x.2008.00482.x
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2
Interferon-β reduces the mouse liver fibrosis induced by repeated administration of concanavalin A via the direct and indirect effects
Autor: Yasushi Miyauchi, Saburo Sone, Hiromi Tsuchiyama, Akiko Izawa, Kazuki Ando, Yuichi Torii, Tomohiko Suzuki, Natsumi Takemi, Jun-Ichi Tanabe
Publikováno v: Immunology. 122:562-570
Type I interferons (IFNs), IFN-alpha and IFN-beta, are widely used for treating chronic hepatitis C. Although retrospective studies have suggested that type I IFNs have direct antifibrotic effects, little is known about these mechanisms. The present
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575db9d34fe4a8bbc4e755e12da00466
https://doi.org/10.1111/j.1365-2567.2007.02672.x
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3
The combination of type I interferon and ribavirin has an inhibitory effect on mouse hepatitis virus infection
Autor: Akiko Izawa, Hideki Narumi, Fumihiro Taguchi, Akemi Kajita, Jun-Ichi Tanabe, Saburo Sone
Publikováno v: Hepatology Research. 37:121-126
We studied the effect of combination therapy consisting of IFN-β and ribavirin on mouse hepatitis virus (MHV) infection in mice. It was found that the combination of IFN-α and ribavirin was more effective in increasing survival time than IFN-α tre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b370d16cba6ccb9d63ff3dcb921cf550
https://doi.org/10.1111/j.1872-034x.2007.00017.x
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4
The roles of CD81 and glycosaminoglycans in the adsorption and uptake of infectious HCV particles
Autor: Daisuke Akazawa, Michiko Miyamoto, Kenichi Morikawa, Asako Murayama, Zijiang Zhao, Tomoko Date, Saburo Sone, Jun-Ichi Tanabe, Takaji Wakita
Publikováno v: Journal of Medical Virology. 79:714-723
Because appropriate cell-culture systems or small-animal models have been lacking, the early steps in the HCV life cycle have been difficult to study. A cell culture system was developed recently that allows production of infectious HCV. In this stud
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c86d15e684917cfefb7f6796b4c986
https://doi.org/10.1002/jmv.20842
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6
Induction of neutrophil chemotactic factor production by staurosporine in rat peritoneal neutrophils
Autor: Jun-ichi Tanabe, Kazuo Ohuchi, Suetsugu Mue, Takeo Edamatsu, Yi-Qun Xiao
Publikováno v: British Journal of Pharmacology. 121:1651-1658
1 Incubation of rat peritoneal neutrophils in medium containing various concentrations of staurosporine (6.4–64 nM) increased the neutrophil chemotactic activity in the conditioned medium in a time- and concentration-dependent manner. 2 Separation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fbf97a2d8a82aff73030a1fd3d2a2f8
https://doi.org/10.1038/sj.bjp.0701322
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7
Dexamethasone inhibits the production of macrophage inflammatory protein 2 in the leukocytes in rat allergic inflammation
Autor: Suetsugu Mue, Jun-ichi Tanabe, Masako Watanabe, Kazuo Ohuchi
Publikováno v: European Journal of Pharmacology. 284:257-263
In the air pouch-type allergic inflammation model in rats, when the infiltrated leukocytes in the pouch fluid collected 4 h after antigen challenge were incubated, neutrophil chemotactic activity in the conditioned medium increased time-dependently.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310a63d090a9755fb65a175f782bedd4
https://doi.org/10.1016/0014-2999(95)00336-j
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8
Characterization of Leukocyte-Derived Neutrophil Chemotactic Factor-2 and Its Possible Roles in Neutrophil Infiltration in Allergic Inflammation in Rats
Autor: Jun-ichi Tanabe, Masako Watanabe, Suetsugu Mue, Naoko Fujimoto, Kazuo Ohuchi
Publikováno v: International Archives of Allergy and Immunology. 108:148-157
This study sought to clarify the responsible chemotactic factor for neutrophils in allergic inflammation in rats. When the leukocytes collected from the pouch fluid 4 h after injection of the antigen solution into the air pouch were incubated, the ne
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c632874c84dfc9ad3d44419027a906
https://doi.org/10.1159/000237132
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