Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jun-Ichi Tanabe"'
Autor:
Tetsuya Ishikawa, Shinichi Kakumu, Ken Sato, Haruhisa Nakao, Tomohiko Ohashi, Akihiko Okumura, Jun-Ichi Tanabe, Minoru Ayada, Hiroyasu Ito, Teiji Kuzuya, Naoki Hotta, Masashi Yoneda
Publikováno v:
Hepatology Research. 39:510-519
Aim Human hepatocytes are known to express an array of inflammatory cytokines and chemokines. In this study, we examined the potential roles of hepatocytes in regulating immune responses in the liver, by assessing the induction of Th1- or Th2-specifi
Autor:
Yasushi Miyauchi, Saburo Sone, Hiromi Tsuchiyama, Akiko Izawa, Kazuki Ando, Yuichi Torii, Tomohiko Suzuki, Natsumi Takemi, Jun-Ichi Tanabe
Publikováno v:
Immunology. 122:562-570
Type I interferons (IFNs), IFN-alpha and IFN-beta, are widely used for treating chronic hepatitis C. Although retrospective studies have suggested that type I IFNs have direct antifibrotic effects, little is known about these mechanisms. The present
Publikováno v:
Hepatology Research. 37:121-126
We studied the effect of combination therapy consisting of IFN-β and ribavirin on mouse hepatitis virus (MHV) infection in mice. It was found that the combination of IFN-α and ribavirin was more effective in increasing survival time than IFN-α tre
Autor:
Daisuke Akazawa, Michiko Miyamoto, Kenichi Morikawa, Asako Murayama, Zijiang Zhao, Tomoko Date, Saburo Sone, Jun-Ichi Tanabe, Takaji Wakita
Publikováno v:
Journal of Medical Virology. 79:714-723
Because appropriate cell-culture systems or small-animal models have been lacking, the early steps in the HCV life cycle have been difficult to study. A cell culture system was developed recently that allows production of infectious HCV. In this stud
Autor:
Koichi Kadota, Masafumi Oguro, Masato Tsujisawa, Tomoyuki Shibahara, Jun-ichi Tanabe, Minoru Hoshino, Yuichi Tosaka
Publikováno v:
Journal of the Japan Veterinary Medical Association. 59:135-139
Induction of neutrophil chemotactic factor production by staurosporine in rat peritoneal neutrophils
Publikováno v:
British Journal of Pharmacology. 121:1651-1658
1 Incubation of rat peritoneal neutrophils in medium containing various concentrations of staurosporine (6.4–64 nM) increased the neutrophil chemotactic activity in the conditioned medium in a time- and concentration-dependent manner. 2 Separation
Publikováno v:
European Journal of Pharmacology. 284:257-263
In the air pouch-type allergic inflammation model in rats, when the infiltrated leukocytes in the pouch fluid collected 4 h after antigen challenge were incubated, neutrophil chemotactic activity in the conditioned medium increased time-dependently.
Publikováno v:
International Archives of Allergy and Immunology. 108:148-157
This study sought to clarify the responsible chemotactic factor for neutrophils in allergic inflammation in rats. When the leukocytes collected from the pouch fluid 4 h after injection of the antigen solution into the air pouch were incubated, the ne
Publikováno v:
Journal of the Japan Veterinary Medical Association. 48:900-904
Publikováno v:
Ensho. 15:115-121