Výsledky vyhledávání - "Jun-Ichi Sakabe"

Akademický článek

A Phenotypic Analysis of Involucrin–Membrane-Bound Ovalbumin Mice after Adoptive Transfer of Ovalbumin-Specific CD8+ T Cells

Autor: Yujin Nakagawa, Gyohei Egawa, Toshiya Miyake, Saeko Nakajima, Atsushi Otsuka, Takashi Nomura, Akihiko Kitoh, Teruki Dainichi, Jun-ichi Sakabe, Akihiko Shibaki, Yoshiki Tokura, Tetsuya Honda, Kenji Kabashima

Publikováno v: JID Innovations, Vol 2, Iss 5, Pp 100127- (2022)

To investigate the mechanism of autoimmunity and peripheral tolerance in the skin, several transgenic mouse strains expressing membrane-bound ovalbumin (mOVA) as an epidermal self-antigen under the control of keratinocyte-specific promotors, such as

Externí odkaz: https://doaj.org/article/cc9afb1b707a4e0680a8d324586938f6

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Akademický článek

Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence

Autor: Stéphanie Claudinot, Jun-Ichi Sakabe, Hideo Oshima, Christèle Gonneau, Thimios Mitsiadis, Daniel Littman, Paola Bonfanti, Geert Martens, Michael Nicolas, Ariane Rochat, Yann Barrandon

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

Adult stem cells are thought to be fate restricted to lineages distinct to their tissue of origin. Here, the authors demonstrate that Tp63 expressing epithelial stem cells from several disparate tissues can respond to skin morphogenetic signals and c

Externí odkaz: https://doaj.org/article/be9d6acf12fb439aa5de18cc8884d19d

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Akademický článek

Plasmacytoid dendritic cells as a possible key player to initiate alopecia areata in the C3H/HeJ mouse

Autor: Taisuke Ito, Takahiro Suzuki, Jun-ichi Sakabe, Atsuko Funakoshi, Toshiharu Fujiyama, Yoshiki Tokura

Publikováno v: Allergology International, Vol 69, Iss 1, Pp 121-131 (2020)

Background: Alopecia areata (AA) is a tissue-specific autoimmune disease, and interferon (IFN)-γ has been regarded as the key cytokine in the pathogenesis of AA. The clinical observation that AA can occur after viral infection or IFN-α administrati

Externí odkaz: https://doaj.org/article/0ea6eb3ac5904eddad44c6144d257da4

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Akademický článek

Antihistaminic drug olopatadine downmodulates T cell chemotaxis toward CCL17 in patients with atopic dermatitis

Autor: Taisuke Ito, Kazuki Tatsuno, Jun-ichi Sakabe, Toshiharu Fujiyama, Yoshiki Tokura

Publikováno v: Allergology International, Vol 64, Iss 2, Pp 200-202 (2015)

Externí odkaz: https://doaj.org/article/9e97e988b71845cc994c2f79f96dbe97

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Akademický článek

Gross cystic disease fluid protein 15 in stratum corneum is a potential marker of decreased eccrine sweating for atopic dermatitis.

Autor: Koji Kamiya, Jun-Ichi Sakabe, Hayato Yamaguchi, Takahiro Suzuki, Tsuyoshi Yatagai, Masahiro Aoshima, Taisuke Ito, Yoshiki Tokura

Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0125082 (2015)

It is well known that eccrine sweating is attenuated in patients with atopic dermatitis (AD). We have reported by using proteome analysis that gross cystic disease fluid protein 15 (GCDFP15), a substance secreted from eccrine sweat glands, is decreas

Externí odkaz: https://doaj.org/article/ee7d7af269b04a27b2d756afac95caa4

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