Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jun-Ichi Kazami"'
Autor:
Ryuji Tsuzuki, Katsumi Sudoh, Susumu Watanuki, Jun-Ichi Kazami, Shin-ichi Tsukamoto, Isao Yanagisawa, Tatsuhiro Tokunaga, Hironori Harada, Akihiro Tanaka, Akira Fujimori
Publikováno v:
Chemical and Pharmaceutical Bulletin. 49:1593-1603
In the previous paper, we described a series of the 2-arylethenesulfonamide derivatives, a novel class of ETA-selective endothelin (ET) receptor antagonists, including the compounds 1a, b. Compound 1a showed excellent oral antagonistic activities and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f740f68a330e019f1488ddd6c02401
https://doi.org/10.1248/cpb.49.1593
https://doi.org/10.1248/cpb.49.1593
Autor:
Shin-ichi Tsukamoto, Ryuji Tsuzuki, Jun-Ichi Kazami, Isao Yanagisawa, Katsumi Sudoh, Hironori Harada, Akira Fujimori, Susumu Watanuki, Akihiro Tanaka
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 49:606-612
In the present article we wish to report the discovery of a novel class of ET(A)-selective endothelin (ET) receptor antagonists through the modification of the ET(A)/ET(B) non-selective antagonist, Ro47-0203 (Bosentan, 1). Replacement of the benzenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dda09927e3804619ea3ab518784bdf4
https://doi.org/10.1248/cpb.49.606
https://doi.org/10.1248/cpb.49.606
Autor:
Susumu Watanuki, Akihiro Tanaka, Isao Yanagisawa, Katsumi Sudoh, Shin-ichi Tsukamoto, Akira Fujimori, Hironori Harada, Jun-Ichi Kazami, Ryuji Tsuzuki
Publikováno v:
ChemInform. 32
In the present article we wish to report the discovery of a novel class of ET(A)-selective endothelin (ET) receptor antagonists through the modification of the ET(A)/ET(B) non-selective antagonist, Ro47-0203 (Bosentan, 1). Replacement of the benzenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b153596b81e32e94947f9244b9571f4a
https://doi.org/10.1002/chin.200146149
https://doi.org/10.1002/chin.200146149
Autor:
Susumu Watanuki, Akihiro Tanaka, Akira Fujimori, Isao Yanagisawa, Ryuji Tsuzuki, Shin-ichi Tsukamoto, Jun-Ichi Kazami, Katsumi Sudoh, Tatsuhiro Tokunaga, Hironori Harada
Publikováno v:
ChemInform. 33
In the previous paper, we described a series of the 2-arylethenesulfonamide derivatives, a novel class of ETA-selective endothelin (ET) receptor antagonists, including the compounds 1a, b. Compound 1a showed excellent oral antagonistic activities and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55226cee8a2ba9585aa6494f8bfcfcab
https://doi.org/10.1002/chin.200217147
https://doi.org/10.1002/chin.200217147
Publikováno v:
The Journal of Antibiotics. 43:1077-1081
The temperature-dependent and concentration-dependent 1H NMR studies as well as 13C-relaxation experiments on gilvocarcin V tetraacetate strongly suggest intermolecular stacking of the antibiotic solution.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ca00ef822e87d72f933da6633df391
https://doi.org/10.7164/antibiotics.43.1077
https://doi.org/10.7164/antibiotics.43.1077
Autor:
Hideaki Nakahara, Susumu Watanuki, Masanao Sanagi, Masaya Orita, Akihiro Tanaka, Katsumi Sudoh, Shin-ichi Tsukamoto, Ryuji Tsuzuki, Jun-Ichi Kazami, Akira Fujimori, Hironori Harada, Isao Yanagisawa, Jun Shimaya
Publikováno v:
Bioorganicmedicinal chemistry. 9(11)
In the previous paper, we described a series of 2-phenylethenesulfonamide derivatives, a novel class of ET(A)-selective endothelin (ET) receptor antagonists, including the 2-methoxyethoxy derivative 2a and the 2-fluoroethoxy derivative (2b). In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccc8c06fe302efd516309b6026de6d1
https://pubmed.ncbi.nlm.nih.gov/11597477
https://pubmed.ncbi.nlm.nih.gov/11597477