Zobrazeno 1 - 10
of 536
pro vyhledávání: '"Jun-Ichi Abe"'
Autor:
Khanh M. Chau, Abishai Dominic, Eleanor L. Davis, Sivareddy Kotla, Estefani Turcios Berrios, Arsany Fahim, Ashwin Arunesh, Shengyu Li, Dongyu Zhao, Kaifu Chen, Alan R. Davis, Minh T. H. Nguyen, Yongxing Wang, Scott E. Evans, Guangyu Wang, John P. Cooke, Jun-ichi Abe, David P. Huston, Nhat-Tu Le
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2024)
BackgroundTraf2 and Nck-interacting kinase (TNIK) is known for its regulatory role in various processes within cancer cells. However, its role within endothelial cells (ECs) has remained relatively unexplored.MethodsLeveraging RNA-seq data and Ingenu
Externí odkaz:
https://doaj.org/article/8f5bf8c0dfad4de7bc1d2a5c762d2c0e
Autor:
Sanjeev Gurshaney, Anamaria Morales-Alvarez, Kevin Ezhakunnel, Andrew Manalo, Thien-Huong Huynh, Jun-Ichi Abe, Nhat-Tu Le, Daniela Weiskopf, Alessandro Sette, Daniel S. Lupu, Stephen J. Gardell, Hung Nguyen
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Mitophagy inhibition rescues cellular dysfunction through enhancing metabolic fitness in CD8 and NKT lymphocytes during SARS-CoV-2 infection.
Externí odkaz:
https://doaj.org/article/9aade89ad179404b824494c7ad2a81d4
Autor:
Ashita Jain, Diego Casanova, Alejandra Valdivia Padilla, Angelica Paniagua Bojorges, Sivareddy Kotla, Kyung Ae Ko, Venkata S. K. Samanthapudi, Khanh Chau, Minh T. H. Nguyen, Jake Wen, Selina L. Hernandez Gonzalez, Shaefali P. Rodgers, Elizabeth A. Olmsted-Davis, Dale J. Hamilton, Cielito Reyes-Gibby, Sai-Ching J. Yeung, John P. Cooke, Joerg Herrmann, Eduardo N. Chini, Xiaolei Xu, Syed Wamique Yusuf, Momoko Yoshimoto, Philip L. Lorenzi, Brain Hobbs, Sunil Krishnan, Efstratios Koutroumpakis, Nicolas L. Palaskas, Guangyu Wang, Anita Deswal, Steven H. Lin, Jun-ichi Abe, Nhat-Tu Le
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality, especially among the aging population. The “response-to-injury” model proposed by Dr. Russell Ross in 1999 emphasizes inflammation as a critical factor in atherosclerosis
Externí odkaz:
https://doaj.org/article/f88dfe27f863446b91fe021a59c753ff
Autor:
Minh T. H. Nguyen, Masaki Imanishi, Shengyu Li, Khanh Chau, Priyanka Banerjee, Loka reddy Velatooru, Kyung Ae Ko, Venkata S. K. Samanthapudi, Young J. Gi, Ling-Ling Lee, Rei J. Abe, Elena McBeath, Anita Deswal, Steven H. Lin, Nicolas L. Palaskas, Robert Dantzer, Keigi Fujiwara, Mae K. Borchrdt, Estefani Berrios Turcios, Elizabeth A. Olmsted-Davis, Sivareddy Kotla, John P. Cooke, Guangyu Wang, Jun-ichi Abe, Nhat-Tu Le
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundThe deSUMOylase sentrin-specific isopeptidase 2 (SENP2) plays a crucial role in atheroprotection. However, the phosphorylation of SENP2 at T368 under disturbed flow (D-flow) conditions hinders its nuclear function and promotes endothelial c
Externí odkaz:
https://doaj.org/article/b6f1e08e085d437dabddc7e3719fecfb
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/64fdb8f025b9444396aa74563c0c7f72
Autor:
Priyanka Banerjee, Julia Enterría Rosales, Khanh Chau, Minh T. H. Nguyen, Sivareddy Kotla, Steven H. Lin, Anita Deswal, Robert Dantzer, Elizabeth A. Olmsted-Davis, Hung Nguyen, Guangyu Wang, John P. Cooke, Jun-ichi Abe, Nhat-Tu Le
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Cancer survivors undergone treatment face an increased risk of developing atherosclerotic cardiovascular disease (CVD), yet the underlying mechanisms remain elusive. Recent studies have revealed that chemotherapy can drive senescent cancer cells to a
Externí odkaz:
https://doaj.org/article/cec1f71c867b45be903698f6ffeae7b5
Autor:
Masaki Imanishi, Haizi Cheng, Sivareddy Kotla, Anita Deswal, Nhat-Tu Le, Eduardo Chini, Kyung Ae Ko, Venkata S. K. Samanthapudi, Ling-Ling Lee, Joerg Herrmann, Xiaolei Xu, Cielito Reyes-Gibby, Sai-Ching J. Yeung, Keri L. Schadler, Syed Wamique Yusuf, Zhongxing Liao, Roza Nurieva, El-ad David Amir, Jared K. Burks, Nicolas L. Palaskas, John P. Cooke, Steven H. Lin, Michihiro Kobayashi, Momoko Yoshimoto, Jun-ichi Abe
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Radiation therapy (RT) to the chest increases the patients’ risk of cardiovascular disease (CVD). A complete understanding of the mechanisms by which RT induces CVD could lead to specific preventive, therapeutic approaches. It is becoming evident t
Externí odkaz:
https://doaj.org/article/6c82a8a9e03240958e5165106910937e
Autor:
Yin Wang, Jun-ichi Abe, Khanh M. Chau, Yongxing Wang, Hang Thi Vu, Loka Reddy Velatooru, Fahad Gulraiz, Masaki Imanishi, Venkata S. K. Samanthapudi, Minh T. H. Nguyen, Kyung Ae Ko, Ling-Ling Lee, Tamlyn N. Thomas, Elizabeth A. Olmsted-Davis, Sivareddy Kotla, Keigi Fujiwara, John P. Cooke, Di Zhao, Scott E. Evans, Nhat-Tu Le
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
We have shown that membrane-associated guanylate kinase with inverted domain structure-1 (MAGI1), a scaffold protein with six PSD95/DiscLarge/ZO-1 (PDZ) domains, is involved in the regulation of endothelial cell (EC) activation and atherogenesis in m
Externí odkaz:
https://doaj.org/article/ff9175760c8b4d4ca6154d8ed9b75802
Autor:
Adam Cornwell, Rohith Palli, Meera V. Singh, Lauren Benoodt, Alicia Tyrell, Jun-ichi Abe, Giovanni Schifitto, Sanjay B. Maggirwar, Juilee Thakar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract People living with HIV are at higher risk of atherosclerosis (AS). The pathogenesis of this risk is not fully understood. To assess the regulatory networks involved in AS we sequenced mRNA of the peripheral blood mononuclear cells (PBMCs) an
Externí odkaz:
https://doaj.org/article/50c82d93ef8840fd8ec8d9ebf2e6750a
Autor:
Minh T.H. Nguyen, Shengyu Li, Imanishi Masaki, Loka Reddy Velatoorua, Priyanka Banerjeea, Rei Abe, Kyung Ae Ko, Sivareddy Kotla, Young Jin Gi, John J. Cooke, Keigi Fujiwarab, Mae K. Borchrdt, Guangyu Wang, Jun-ichi Abe, Nhat-Tu Le
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 420- (2022)
Externí odkaz:
https://doaj.org/article/fe19a065599f4d5ba06808f99c1e46eb