Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jun-Hua Nie"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14385 (2022)
Anaplastic thyroid cancer is an extremely lethal malignancy without reliable treatment. BRAFV600E point mutation is common in ATCs, which leads to MAPK signaling activation and is regarded as a therapeutic target. Resveratrol inhibits ATC cell growth
Externí odkaz:
https://doaj.org/article/dc624f75a5a44577a912e72299a39982
Autor:
Jun-Hua Nie, Tao Yang, Hong Li, Hai-Shan Ye, Guo-Qing Zhong, Ting-Ting Li, Chi Zhang, Wen-Han Huang, Jin Xiao, Zhi Li, Jian-Li He, Bo-Le Du, Yu Zhang, Jia Liu
Publikováno v:
Journal of Bone Oncology, Vol 30, Iss , Pp 100391- (2021)
Background: Drug resistance and the lack of molecular therapeutic target are the main challenges in the management of osteosarcomas (OSs). Identification of novel genetic alteration(s) related with OS recurrence and chemotherapeutic resistance would
Externí odkaz:
https://doaj.org/article/0efd2147890a4f39be824f4082c7ac83
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10622 (2021)
Glioblastoma multiforme (GBM) is the most common lethal primary brain malignancy without reliable therapeutic drugs. IL-13Rα2 is frequently expressed in GBMs as a molecular marker. Resveratrol (Res) effectively inhibits GBM cell growth but has not b
Externí odkaz:
https://doaj.org/article/f3506cae74594b1c9f94f564e65ed2b2
Publikováno v:
Non-Coding RNA, Vol 5, Iss 2, p 36 (2019)
One of modern biology’s great surprises is that the human genome encodes only ~20,000 protein-coding genes, which represents less than 2% of the total genome sequence, and the majority of them are transcribed into non-coding RNAs (ncRNAs). Increasi
Externí odkaz:
https://doaj.org/article/6cf7235fcea541c68b24c47835031d7e
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 191 (2019)
Glioblastoma multiforme (GBM) is the commonest primary brain malignancy with extremely poor prognosis. Resveratrol posseses anti-cancer effects, while GBM cells respond differently to it due to certain unknown reason(s). Because the tumor-derived exo
Externí odkaz:
https://doaj.org/article/4d10915a71ee42bfa428014e460efacc
Publikováno v:
Nanotheranostics. 5:143-154
Background: Docetaxel and doxorubicin combination has been widely used in anaplastic thyroid cancer/ATC treatment but often results in serious adverse effects and drug resistance. Resveratrol effectively inhibits ATC cell proliferation in vitro witho
Autor:
Hai‐Shan Ye, Hong‐Fei Gao, Hong Li, Jun‐Hua Nie, Ting‐Ting Li, Meng‐Di Lu, Mo‐Li Wu, Jia Liu, Kun Wang
Publikováno v:
Phytotherapy research : PTRREFERENCES. 36(8)
The lack of reliable drugs is a therapeutic challenge of advanced breast cancers (ABCs). Resveratrol (Res) exerts inhibitory effects on breast cancer cell lines and animal models, while its efficacy against individual breast cancer cases remains unkn
Autor:
Hong Li, Jia Liu, Hai-Shan Ye, Meng-Di Lu, Ting-Ting Li, Mo-Li Wu, Kun Wang, Hong-Fei Gao, Jun-Hua Nie
Background: The lack of reliable drugs is a therapeutic challenge of advanced breast cancers (ABCs). Resveratrol (Res) exerts inhibitory effects on breast cancer cell lines and animal models, while its efficacy against individual breast cancer cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1afbe47bedb0047428f364e3e9f1bf8b
https://doi.org/10.21203/rs.3.rs-970702/v1
https://doi.org/10.21203/rs.3.rs-970702/v1
Autor:
Hong Li, Jun-Hua Nie, Tao Yang, Bo-Le Du, Guo-Qing Zhong, Jin Xiao, Yu Zhang, Ting-Ting Li, Zhi Li, Hai-Shan Ye, Chi Zhang, Jia Liu, Jian-Li He, Wen-Han Huang
Publikováno v:
Journal of Bone Oncology, Vol 30, Iss, Pp 100391-(2021)
Journal of Bone Oncology
Journal of Bone Oncology
Highlights • GPC3 mutation in primary osteosarcoma becomes abundant in its metastasis. • Mutant GPC3 is over-produced in metastatic spheroids with multidrug resistance. • Anti-GPC3 antibody effectively commits metastatic spheroids to apoptosis.
Publikováno v:
Nanotheranostics
Background: Docetaxel and doxorubicin combination has been widely used in anaplastic thyroid cancer/ATC treatment but often results in serious adverse effects and drug resistance. Resveratrol effectively inhibits ATC cell proliferation in vitro witho