Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jun-Ho Ahn"'
Autor:
Mi-Ok Lee, Su-gi Lee, Cho-Rok Jung, Ye Seul Son, Jae-Woon Ryu, Kwang Bo Jung, Jun-Ho Ahn, Jung-Hwa Oh, Hyang-Ae Lee, Jung Hwa Lim, Janghwan Kim, Insu Jang, Jinhyuk Choi, Jaeeun Jung, Kunhyang Park, Byungwook Lee, Dae-Soo Kim, Mi-Young Son, Hyun-Soo Cho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Quantitative methods to assess the quality of hPSC-derived organoids have not been developed. Here they present a prediction algorithm to assess the transcriptomic similarity between hPSC-derived organoids and the corresponding human target organs an
Externí odkaz:
https://doaj.org/article/27708e935ee5482783e2d1c6359a3d60
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-15 (2019)
Abstract Background Various hepatic models mimicking liver lobules have been investigated to evaluate the potential hepatotoxic effects of chemicals and drugs, but in vitro hepatic models of zonal hepatotoxicity have not yet been established. Herein,
Externí odkaz:
https://doaj.org/article/96ea80e7fe184d5b8a22ebdb7f1a2725
Autor:
Yu Hwa Choi, Young Ae Kang, Kwang Joo Park, Jae Chol Choi, Kwan Goo Cho, Da Yeon Ko, Jun Ho Ahn, Boram Lee, Eunsol Ahn, Yun Ju Woo, Kwangsoo Jung, Nan Yul Kim, Valerie A. Reese, Sasha E. Larsen, Susan L. Baldwin, Steven G. Reed, Rhea N. Coler, Hyejon Lee, Sang-Nae Cho
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 6, Pp 1605-1624 (2023)
Abstract Introduction This randomized, double-blind, placebo-controlled, phase 2a trial was conducted to evaluate the safety and immunogenicity of the ID93 + glucopyranosyl lipid adjuvant (GLA)-stable emulsion (SE) vaccine in human immunodeficiency v
Externí odkaz:
https://doaj.org/article/b0f1ce14fe714639abe443b60b0ec5bc
Autor:
Jaehwan Ahn, Kwang Bo Jung, Ohman Kwon, Jun-Ho Ahn, Jung-Hwa Oh, Seokjoo Yoon, Hyoung-Yun Han, Mi-Sun Choi, Mi-Young Son, Cho-Rok Jung
Publikováno v:
Analytical Chemistry. 93:8826-8834
Human pluripotent stem cell (hPSC)-derived intestinal organoids (HIOs) hold unprecedented promise for basic biology and translational applications. However, developing a quantitative method to evaluate the epithelial cell membrane integrity of HIOs a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d501bc2e0a2430e6b31aa38f57f1ef21
https://doi.org/10.1021/acs.analchem.1c00655
https://doi.org/10.1021/acs.analchem.1c00655
Publikováno v:
Food Science and Biotechnology. 30:853-860
Bacillus amyloliquefaciens S0904 was selected as a hyperproducer of a glutamine-hydrolyzing enzyme which was identified as a γ-glutamyltranspeptidase catalyzing both hydrolysis and transpeptidation of glutamyl substrates. The signal peptide-truncate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b7c43acc80d3769e0f21fbeb8f48562
https://doi.org/10.1007/s10068-021-00928-6
https://doi.org/10.1007/s10068-021-00928-6
Autor:
Soo Jin Kim, Se-Myo Park, Jung-Hwa Oh, Mi-Sun Choi, Hyun Jegal, Hyoung-Yun Han, Jun-Ho Ahn, Seokjoo Yoon, Hyun-Soo Cho, Jaehwan Ahn
Publikováno v:
Toxicology Letters. 342:73-84
Trovafloxacin (TVX) is associated with idiosyncratic drug-induced liver injury (iDILI) and inflammation-mediated hepatotoxicity. However, the inflammatory stress-regulated mechanisms in iDILI remain unclear. Herein, we elucidated the novel role of tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8bdc9262997de7dc586002ef267d6d
https://doi.org/10.1016/j.toxlet.2021.02.009
https://doi.org/10.1016/j.toxlet.2021.02.009
Publikováno v:
Genes & Genomics. 41:1273-1280
Acquired resistance is a significant clinical challenge in targeted therapy of melanomas using BRAF inhibitors. We previously identified that downregulation of miR-92a-1-5p confers acquired resistance to BRAF inhibition using an miRNA array platform.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c03c643c2f577864917e606f1810daf
https://doi.org/10.1007/s13258-019-00856-0
https://doi.org/10.1007/s13258-019-00856-0
Publikováno v:
Biomolecules & Therapeutics
Melanoma cells have been shown to respond to BRAF inhibitors; however, intrinsic and acquired resistance limits their clinical application. In this study, we performed RNA-Seq analysis with BRAF inhibitor-sensitive (A375P) and -resistant (A375P/Mdr w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c5d511e395d4135dcd66f97c200e8c
https://doi.org/10.4062/biomolther.2018.133
https://doi.org/10.4062/biomolther.2018.133
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-15 (2019)
Journal of Biological Engineering
Journal of Biological Engineering
Background Various hepatic models mimicking liver lobules have been investigated to evaluate the potential hepatotoxic effects of chemicals and drugs, but in vitro hepatic models of zonal hepatotoxicity have not yet been established. Herein, we devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b8320357ba3a0a89aa9e802da462c6
http://link.springer.com/article/10.1186/s13036-019-0148-5
http://link.springer.com/article/10.1186/s13036-019-0148-5
Publikováno v:
Food Sci Biotechnol
Bacillus amyloliquefaciens S0904 was selected as a hyperproducer of a glutamine-hydrolyzing enzyme which was identified as a γ-glutamyltranspeptidase catalyzing both hydrolysis and transpeptidation of glutamyl substrates. The signal peptide-truncate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0ef87b9622c96afae0835a83feba0b8
https://pubmed.ncbi.nlm.nih.gov/34249391
https://pubmed.ncbi.nlm.nih.gov/34249391