Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jun-Dong Wei"'
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 403-412 (2023)
ABSTRACTColorectal cancer (CRC) is the most common malignant tumor and one of the leading causes of cancer-related death worldwide. Oncogene KRAS is a commonly mutated in CRC and plays crucial roles in the colorectal tumorigenesis. Emerging evidence
Externí odkaz:
https://doaj.org/article/701425cc4f944f00bd9d52a804b6c3fa
Autor:
Jun-Dong Wei, Jae-Hong Kim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
BLT2 is a low-affinity leukotriene B4 receptor that plays an essential role in the pathogenesis of various inflammatory diseases, including asthma and cancer. BLT2 is minimally expressed in a normal internal environment but is overexpressed in a stre
Externí odkaz:
https://doaj.org/article/0008753ad6e34729bcca1ef34b7779ea
Autor:
Jun-Dong Wei, Xueming Xu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Wernicke’s encephalopathy (WE) is a severe life-threatening disease that occurs due to vitamin B1 (thiamine) deficiency (TD). It is characterized by acute mental disorder, ataxia, and ophthalmoplegia. TD occurs because of the following reasons: ins
Externí odkaz:
https://doaj.org/article/e6f3c9b1e8914abe83f1413c0c2629da
Autor:
Hyejun Park, Dipesh S. Harmalkar, Jun-Dong Wei, Seunghan Sun, Jinsun Kwon, Chang Hoon Lee, Jae Geun Song, Hyo-Kyung Han, Jae-Hong Kim, Kyeong Lee, Yongseok Choi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c3284b06a14583cdc87ca7e800654a3
https://doi.org/10.2139/ssrn.4454238
https://doi.org/10.2139/ssrn.4454238
Autor:
Kyeong Lee, Ja Il Goo, Jae Hong Kim, Yongseok Choi, Art E. Cho, Dipesh S. Harmalkar, Jun Dong Wei, Minsup Kim
Publikováno v:
ACS Medicinal Chemistry Letters. 11:1529-1534
G protein-coupled receptors (GPCRs) have always been important drug targets in the pharmaceutical industry. One major question for the current GPCR drug discovery is how drugs have distinct efficacies at the same GPCR target. Related to this question
Autor:
Minsup, Kim, Jun-Dong, Wei, Dipesh S, Harmalkar, Ja-Il, Goo, Kyeong, Lee, Yongseok, Choi, Jae-Hong, Kim, Art E, Cho
Publikováno v:
ACS Med Chem Lett
[Image: see text] G protein-coupled receptors (GPCRs) have always been important drug targets in the pharmaceutical industry. One major question for the current GPCR drug discovery is how drugs have distinct efficacies at the same GPCR target. Relate
Publikováno v:
International Journal of Molecular Medicine
Wogonin, a naturally occurring bioactive monoflavonoid isolated from Scutellariae radix (roots of Scutellariae baicalensis Georgi), has known anticancer effects. However, the molecular signaling mechanism by which wogonin inhibits invasiveness in bre
Publikováno v:
Biochemical and biophysical research communications. 483(1)
RanBPM is a scaffolding protein that regulates several cellular processes by interacting with various proteins. Previously, we reported that RanBPM acts as a negative regulator of BLT2, a low-affinity leukotriene B4 receptor; thus, it interferes with
Autor:
Minsup Kim, Jun-Dong Wei, Harmalkar, Dipesh S., Ja-il Goo, Kyeong Lee, Yongseok Choi, Jae-Hong Kim, Cho, Art E.
Publikováno v:
ACS Medicinal Chemistry Letters; 8/13/2020, Vol. 11 Issue 8, p1529-1534, 6p
Publikováno v:
The Journal of Immunology. 184:3946-3954
Recent studies have suggested that mast cells have critical roles in angiogenesis. However, the detailed mechanism by which mast cells contribute to angiogenesis is not yet clearly understood, especially in response to proinflammatory cytokines. In t